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GO:0019985 translesion synthesis

Term Information

ID GO:0019985
Name translesion synthesis
Ontology Biological Process
Definition The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.
PMID:10535901
GONUTS GO:0019985 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact bypass DNA synthesis

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Guidance for interpreting DNA repair investigationsLink

Cross-references

Database ID
InterPro IPR030559

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0019985:
Relationship To GO:0019985 Child Term Child Term Name
Is a GO:0070987 error-free translesion synthesis
Is a GO:0042276 error-prone translesion synthesis

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0019985. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0019985 based on the entire annotation set Co-occurrence statistics for GO:0019985 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2016-06-22 Deleted RELATION is a GO:0044711 (single-organism biosynthetic process)
2016-05-01 Added RELATION is a GO:0000731 (DNA synthesis involved in DNA repair)
2016-05-01 Deleted RELATION is a GO:0071897 (DNA biosynthetic process)
2013-11-28 Added RELATION is a GO:0044711 (single-organism biosynthetic process)
2010-09-17 Added RELATION is a GO:0071897 (DNA biosynthetic process)
2010-09-17 Deleted RELATION is a GO:0006261 (DNA-dependent DNA replication)
2010-02-27 Added RELATION is a GO:0006261 (DNA-dependent DNA replication)
2009-10-30 Added RELATION is a GO:0006301 (postreplication repair)
2009-10-30 Deleted RELATION is a GO:0006281 (DNA repair)
2009-10-30 Added DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.
2009-10-30 Updated TERM translesion synthesis
2009-10-30 Added SYNONYM bypass DNA synthesis
2009-10-30 Deleted DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized replication complex inserts a random nucleotide across from the lesion and then continues DNA synthesis beyond the lesion. This process is often mutagenic.
2008-05-13 Added DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized replication complex inserts a random nucleotide across from the lesion and then continues DNA synthesis beyond the lesion. This process is often mutagenic.
2008-05-12 Deleted DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized replication complex inserts a random nucleotide across from the lesion and then continues DNA synthesis beyond the lesion. This process is often mutagenic.
2008-04-01 Updated RELATION is a GO:0006281 (DNA repair)
2004-07-16 Updated DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized replication complex inserts a random nucleotide across from the lesion and then continues DNA synthesis beyond the lesion. This process is often mutagenic.
2002-11-27 Added DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized replication complex inserts a random nucleotide across from the lesion and then continues DNA synthesis beyond the lesion. This process is mutagenic.
2002-01-11 Added TERM bypass DNA synthesis

Term

Timestamp Action Category Detail
2009-10-30 Updated TERM translesion synthesis
2002-01-11 Added TERM bypass DNA synthesis

Definition/synonyms

Timestamp Action Category Detail
2009-10-30 Added DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.
2009-10-30 Added SYNONYM bypass DNA synthesis
2009-10-30 Deleted DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized replication complex inserts a random nucleotide across from the lesion and then continues DNA synthesis beyond the lesion. This process is often mutagenic.
2008-05-13 Added DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized replication complex inserts a random nucleotide across from the lesion and then continues DNA synthesis beyond the lesion. This process is often mutagenic.
2008-05-12 Deleted DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized replication complex inserts a random nucleotide across from the lesion and then continues DNA synthesis beyond the lesion. This process is often mutagenic.
2004-07-16 Updated DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized replication complex inserts a random nucleotide across from the lesion and then continues DNA synthesis beyond the lesion. This process is often mutagenic.
2002-11-27 Added DEFINITION The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized replication complex inserts a random nucleotide across from the lesion and then continues DNA synthesis beyond the lesion. This process is mutagenic.

Relationships

Timestamp Action Category Detail
2016-06-22 Deleted RELATION is a GO:0044711 (single-organism biosynthetic process)
2016-05-01 Added RELATION is a GO:0000731 (DNA synthesis involved in DNA repair)
2016-05-01 Deleted RELATION is a GO:0071897 (DNA biosynthetic process)
2013-11-28 Added RELATION is a GO:0044711 (single-organism biosynthetic process)
2010-09-17 Added RELATION is a GO:0071897 (DNA biosynthetic process)
2010-09-17 Deleted RELATION is a GO:0006261 (DNA-dependent DNA replication)
2010-02-27 Added RELATION is a GO:0006261 (DNA-dependent DNA replication)
2009-10-30 Added RELATION is a GO:0006301 (postreplication repair)
2009-10-30 Deleted RELATION is a GO:0006281 (DNA repair)
2008-04-01 Updated RELATION is a GO:0006281 (DNA repair)
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