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GO:0019898 extrinsic component of membrane

Term Information

ID GO:0019898
Name extrinsic component of membrane
Ontology Cellular Component
Definition The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
Comment Note that proteins extrinsic to membranes can be removed by treatments that do not disrupt the membrane, such as salt solutions.
Secondary IDs GO:0030396
GONUTS GO:0019898 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact extrinsic to membrane
exact peripheral membrane protein

Cross-references

Database ID
InterPro IPR000798
InterPro IPR002628
InterPro IPR002683
InterPro IPR008797
InterPro IPR010527
InterPro IPR011174
InterPro IPR011259
InterPro IPR030190
Wikipedia Peripheral_membrane_protein

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0000300 peripheral to membrane of membrane fraction CONSIDER GO:0019898

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0019898:
Relationship To GO:0019898 Child Term Child Term Name
Is a GO:0019897 extrinsic component of plasma membrane
Is a GO:0031244 extrinsic component of cell outer membrane
Is a GO:0031312 extrinsic component of organelle membrane
Is a GO:0035448 extrinsic component of thylakoid membrane

Protein Annotation

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GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0019898. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0019898 based on the entire annotation set Co-occurrence statistics for GO:0019898 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-12-21 Updated TERM extrinsic component of membrane
2013-12-21 Deleted DEFINITION Loosely bound to one surface of a membrane, but not integrated into the hydrophobic region.
2013-12-21 Added DEFINITION The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
2013-12-21 Added SYNONYM extrinsic to membrane
2009-02-08 Added XREF Wikipedia:Peripheral_membrane_protein
2008-05-13 Added DEFINITION Loosely bound to one surface of a membrane, but not integrated into the hydrophobic region.
2008-05-12 Deleted DEFINITION Loosely bound to one surface of a membrane, but not integrated into the hydrophobic region.
2008-04-01 Updated RELATION is a GO:0044425 (membrane part)
2007-10-16 Deleted SYNONYM GPI-anchored membrane-bound receptor
2007-08-09 Added SYNONYM GPI-anchored membrane-bound receptor
2007-08-09 Added SYNONYM peripheral membrane protein
2007-08-09 Deleted SYNONYM GPI-anchored membrane-bound receptor
2007-08-09 Deleted SYNONYM peripheral membrane protein
2005-08-10 Added SYNONYM GPI-anchored membrane-bound receptor
2005-03-05 Updated DEFINITION Loosely bound to one surface of a membrane, but not integrated into the hydrophobic region.
2005-02-25 Updated DEFINITION Loosely bound, by ionic or covalent forces, to one surface of a membrane, but not integrated into the hydrophobic region.
2004-04-30 Updated DEFINITION Loosely bound, by ionic or covalent forces, to one or other surface of a membrane, but not integrated into the hydrophobic region.
2004-04-19 Added SYNONYM peripheral membrane protein
2004-04-16 Deleted SYNONYM peripheral membrane protein
2003-03-26 Updated DEFINITION Loosely bound, by ionic or covalent forces, to one or other surface of the cell membrane, but not integrated into the hydrophobic region.
2002-12-17 Updated TERM extrinsic to membrane
2002-11-27 Added DEFINITION An operational term for any protein that can be dissociated unchanged from a cell membrane by a mild treatment such as increase in ionic strength of the medium or addition of a chelating agent to it. Such proteins are presumed to be loosely attached one or other surface of the cell membrane.
2002-01-08 Added SECONDARY GO:0030396 (peripheral membrane protein)
2002-01-08 Added SYNONYM peripheral membrane protein
2002-01-08 Added TERM extrinsic membrane protein

Term

Timestamp Action Category Detail
2013-12-21 Updated TERM extrinsic component of membrane
2002-12-17 Updated TERM extrinsic to membrane
2002-01-08 Added TERM extrinsic membrane protein

Definition/synonyms

Timestamp Action Category Detail
2013-12-21 Deleted DEFINITION Loosely bound to one surface of a membrane, but not integrated into the hydrophobic region.
2013-12-21 Added DEFINITION The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
2013-12-21 Added SYNONYM extrinsic to membrane
2008-05-13 Added DEFINITION Loosely bound to one surface of a membrane, but not integrated into the hydrophobic region.
2008-05-12 Deleted DEFINITION Loosely bound to one surface of a membrane, but not integrated into the hydrophobic region.
2007-10-16 Deleted SYNONYM GPI-anchored membrane-bound receptor
2007-08-09 Added SYNONYM GPI-anchored membrane-bound receptor
2007-08-09 Added SYNONYM peripheral membrane protein
2007-08-09 Deleted SYNONYM GPI-anchored membrane-bound receptor
2007-08-09 Deleted SYNONYM peripheral membrane protein
2005-08-10 Added SYNONYM GPI-anchored membrane-bound receptor
2005-03-05 Updated DEFINITION Loosely bound to one surface of a membrane, but not integrated into the hydrophobic region.
2005-02-25 Updated DEFINITION Loosely bound, by ionic or covalent forces, to one surface of a membrane, but not integrated into the hydrophobic region.
2004-04-30 Updated DEFINITION Loosely bound, by ionic or covalent forces, to one or other surface of a membrane, but not integrated into the hydrophobic region.
2004-04-19 Added SYNONYM peripheral membrane protein
2004-04-16 Deleted SYNONYM peripheral membrane protein
2003-03-26 Updated DEFINITION Loosely bound, by ionic or covalent forces, to one or other surface of the cell membrane, but not integrated into the hydrophobic region.
2002-11-27 Added DEFINITION An operational term for any protein that can be dissociated unchanged from a cell membrane by a mild treatment such as increase in ionic strength of the medium or addition of a chelating agent to it. Such proteins are presumed to be loosely attached one or other surface of the cell membrane.
2002-01-08 Added SYNONYM peripheral membrane protein

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0044425 (membrane part)

Cross-references

Timestamp Action Category Detail
2009-02-08 Added XREF Wikipedia:Peripheral_membrane_protein

Other

Timestamp Action Category Detail
2002-01-08 Added SECONDARY GO:0030396 (peripheral membrane protein)
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