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GO:0019828 aspartic-type endopeptidase inhibitor activity

Term Information

ID GO:0019828
Name aspartic-type endopeptidase inhibitor activity
Ontology Molecular Function
Definition Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.
GONUTS GO:0019828 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact aspartic protease inhibitor activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
UniProtKB-KW Aspartic protease inhibitor

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0019828:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0019828. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0019828 based on the entire annotation set Co-occurrence statistics for GO:0019828 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-06-15 Added RELATION negatively regulates GO:0004190 (aspartic-type endopeptidase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0004190 (aspartic-type endopeptidase activity)
2010-06-08 Added RELATION negatively regulates GO:0004190 (aspartic-type endopeptidase activity)
2009-02-25 Deleted RELATION negatively regulates GO:0004190 (aspartic-type endopeptidase activity)
2009-02-22 Added RELATION negatively regulates GO:0004190 (aspartic-type endopeptidase activity)
2008-08-18 Added DEFINITION Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.
2008-08-18 Deleted DEFINITION Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.
2008-05-13 Added DEFINITION Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.
2008-05-12 Deleted DEFINITION Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.
2008-04-01 Updated RELATION is a GO:0004866 (endopeptidase inhibitor activity)
2007-08-09 Added SYNONYM aspartic protease inhibitor activity
2007-08-09 Deleted SYNONYM aspartic protease inhibitor activity
2004-04-19 Added SYNONYM aspartic protease inhibitor activity
2004-04-16 Deleted SYNONYM aspartic protease inhibitor activity
2004-01-08 Added SYNONYM aspartic protease inhibitor activity
2004-01-08 Updated TERM aspartic-type endopeptidase inhibitor activity
2004-01-08 Added DEFINITION Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.
2003-03-19 Updated TERM aspartic protease inhibitor activity
2001-12-05 Added TERM aspartic protease inhibitor

Term

Timestamp Action Category Detail
2004-01-08 Updated TERM aspartic-type endopeptidase inhibitor activity
2003-03-19 Updated TERM aspartic protease inhibitor activity
2001-12-05 Added TERM aspartic protease inhibitor

Definition/synonyms

Timestamp Action Category Detail
2008-08-18 Added DEFINITION Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.
2008-08-18 Deleted DEFINITION Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.
2008-05-13 Added DEFINITION Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.
2008-05-12 Deleted DEFINITION Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.
2007-08-09 Added SYNONYM aspartic protease inhibitor activity
2007-08-09 Deleted SYNONYM aspartic protease inhibitor activity
2004-04-19 Added SYNONYM aspartic protease inhibitor activity
2004-04-16 Deleted SYNONYM aspartic protease inhibitor activity
2004-01-08 Added SYNONYM aspartic protease inhibitor activity
2004-01-08 Added DEFINITION Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.

Relationships

Timestamp Action Category Detail
2010-06-15 Added RELATION negatively regulates GO:0004190 (aspartic-type endopeptidase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0004190 (aspartic-type endopeptidase activity)
2010-06-08 Added RELATION negatively regulates GO:0004190 (aspartic-type endopeptidase activity)
2009-02-25 Deleted RELATION negatively regulates GO:0004190 (aspartic-type endopeptidase activity)
2009-02-22 Added RELATION negatively regulates GO:0004190 (aspartic-type endopeptidase activity)
2008-04-01 Updated RELATION is a GO:0004866 (endopeptidase inhibitor activity)
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