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GO:0019676 ammonia assimilation cycle

The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.

Term Information

ID GO:0019676
Name ammonia assimilation cycle
Ontology Biological Process
Definition The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.
Comment

Synonyms

Type Synonym
exact glutamate metabolic process via glutamine and ammonia
exact glutamate metabolism via glutamine and ammonia

Cross-references associated with this term:

Database ID
MetaCyc PWY-3282
MetaCyc AMMASSIM-PWY

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Ancestor Table

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GO:0008150 biological_process
GO:0008152 metabolic process
GO:0009987 cellular process
GO:0006807 nitrogen compound metabolic process
GO:0044238 primary metabolic process
GO:0009308 amine metabolic process
GO:0044237 cellular metabolic process
GO:0042180 cellular ketone metabolic process
GO:0006082 organic acid metabolic process
GO:0044106 cellular amine metabolic process
GO:0006519 cellular amino acid and derivative metabolic process
GO:0043436 oxoacid metabolic process
GO:0019752 carboxylic acid metabolic process
GO:0006520 cellular amino acid metabolic process
GO:0009064 glutamine family amino acid metabolic process
GO:0006541 glutamine metabolic process
GO:0006536 glutamate metabolic process
GO:0019676 ammonia assimilation cycle

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

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Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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12ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-11-23-04-03-36
Terminal
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