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GO:0019153 protein-disulfide reductase (glutathione) activity

Catalysis of the reaction: 2 glutathione + protein-disulfide = oxidized glutathione + protein-dithiol.

Term Information

ID GO:0019153
Name protein-disulfide reductase (glutathione) activity
Ontology Molecular Function
Definition Catalysis of the reaction: 2 glutathione + protein-disulfide = oxidized glutathione + protein-dithiol.
Comment

Synonyms

Type Synonym
exact insulin reductase activity
exact protein disulfide transhydrogenase activity
related protein-disulfide interchange enzyme
exact protein-disulfide isomerase/oxidoreductase activity
exact reductase, protein disulfide (glutathione)
exact GSH-insulin transhydrogenase activity
exact glutathione-insulin transhydrogenase activity
exact glutathione-protein disulfide oxidoreductase activity
exact glutathione:protein-disulfide oxidoreductase activity
exact protein disulfide reductase (glutathione)
exact glutathione--insulin transhydrogenase activity
exact thiol:protein-disulfide oxidoreductase activity
exact thiol-protein disulphide oxidoreductase activity
exact protein-disulphide reductase (glutathione) activity
related glutaredoxin reductase

Cross-references associated with this term:

Database ID
MetaCyc PRODISULFREDUCT-RXN
EC 1.8.4.2

This term can be used instead of these obsolete terms:

GO:0006129 protein-disulfide reduction (consider GO:0019153)

Web service: term information

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Ancestor Chart

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Ancestor Table

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016667 oxidoreductase activity, acting on sulfur group of donors
GO:0016671 oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor
GO:0019153 protein-disulfide reductase (glutathione) activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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