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GO:0019005 SCF ubiquitin ligase complexA ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
Term Information
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| Type | Synonym |
| exact | CDL1 complex |
| exact | CRL1 complex |
| exact | Cul1-RING ubiquitin ligase complex |
| exact | SCF complex |
| narrow | SCF complex substrate recognition subunit |
| exact | Skp1/Cul1/F-box protein complex |
| exact | cullin-RING ligase 1 |
| Database | ID |
| Wikipedia | SCF_complex |
GO:0009839 SCF complex substrate recognition subunit |
(replaced_by GO:0019005) |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0005575 cellular_component | |||||||||
![]() | GO:0032991 macromolecular complex | ||||||||
![]() | ![]() | GO:0005623 cell | |||||||
![]() | ![]() | ![]() | GO:0044464 cell part | ||||||
![]() | ![]() | ![]() | ![]() | GO:0043234 protein complex | |||||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0005622 intracellular | ||||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0044424 intracellular part | |||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0000151 ubiquitin ligase complex | ||
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0031461 cullin-RING ubiquitin ligase complex | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0019005 SCF ubiquitin ligase complex |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| I | GO:0043223 cytoplasmic SCF ubiquitin ligase complex |
| I | GO:0043224 nuclear SCF ubiquitin ligase complex |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-23-04-03-36 |