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GO:0018454 acetoacetyl-CoA reductase activity

Term Information

ID GO:0018454
Name acetoacetyl-CoA reductase activity
Ontology Molecular Function
Definition Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.
GONUTS GO:0018454 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact (R)-3-hydroxyacyl-CoA dehydrogenase activity
exact (R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase activity
exact short chain beta-ketoacetyl(acetoacetyl)-CoA reductase activity
exact hydroxyacyl coenzyme-A dehydrogenase activity
broad beta-ketoacyl-CoA reductase
exact acetoacetyl coenzyme A reductase activity
exact NADPH:acetoacetyl-CoA reductase activity
exact NADP-linked acetoacetyl CoA reductase activity
exact D-3-hydroxyacyl-CoA reductase activity
exact D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.1.1.36
InterPro IPR011283
MetaCyc RXN-7698
RHEA 22259
UM-BBD_reactionID r0202

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0018454:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0018454. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0018454 based on the entire annotation set Co-occurrence statistics for GO:0018454 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:22259
2011-05-03 Added XREF UM-BBD_reactionID:r0202
2011-05-03 Deleted XREF UM-BBD_enzymeID:e0005
2009-05-21 Deleted XREF MetaCyc:ACETOACETYL-COA-REDUCTASE-RXN
2009-05-21 Added XREF MetaCyc:RXN-7698
2008-05-13 Added DEFINITION Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.
2008-04-01 Updated RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
2007-11-08 Added SYNONYM (R)-3-hydroxyacyl-CoA dehydrogenase activity
2007-11-08 Added SYNONYM (R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase activity
2007-11-08 Added SYNONYM D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase activity
2007-11-08 Added SYNONYM D-3-hydroxyacyl-CoA reductase activity
2007-11-08 Added SYNONYM NADP-linked acetoacetyl CoA reductase activity
2007-11-08 Added SYNONYM NADPH:acetoacetyl-CoA reductase activity
2007-11-08 Added SYNONYM acetoacetyl coenzyme A reductase activity
2007-11-08 Added SYNONYM beta-ketoacyl-CoA reductase
2007-11-08 Added SYNONYM hydroxyacyl coenzyme-A dehydrogenase activity
2007-11-08 Added SYNONYM short chain beta-ketoacetyl(acetoacetyl)-CoA reductase activity
2003-10-27 Added XREF UM-BBD_enzymeID:e0005
2003-10-27 Added XREF MetaCyc:ACETOACETYL-COA-REDUCTASE-RXN
2003-03-19 Updated TERM acetoacetyl-CoA reductase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.
2001-10-01 Added XREF EC:1.1.1.36
2001-10-01 Added TERM acetoacetyl-CoA reductase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM acetoacetyl-CoA reductase activity
2001-10-01 Added TERM acetoacetyl-CoA reductase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.
2007-11-08 Added SYNONYM (R)-3-hydroxyacyl-CoA dehydrogenase activity
2007-11-08 Added SYNONYM (R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase activity
2007-11-08 Added SYNONYM D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase activity
2007-11-08 Added SYNONYM D-3-hydroxyacyl-CoA reductase activity
2007-11-08 Added SYNONYM NADP-linked acetoacetyl CoA reductase activity
2007-11-08 Added SYNONYM NADPH:acetoacetyl-CoA reductase activity
2007-11-08 Added SYNONYM acetoacetyl coenzyme A reductase activity
2007-11-08 Added SYNONYM beta-ketoacyl-CoA reductase
2007-11-08 Added SYNONYM hydroxyacyl coenzyme-A dehydrogenase activity
2007-11-08 Added SYNONYM short chain beta-ketoacetyl(acetoacetyl)-CoA reductase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:22259
2011-05-03 Added XREF UM-BBD_reactionID:r0202
2011-05-03 Deleted XREF UM-BBD_enzymeID:e0005
2009-05-21 Deleted XREF MetaCyc:ACETOACETYL-COA-REDUCTASE-RXN
2009-05-21 Added XREF MetaCyc:RXN-7698
2003-10-27 Added XREF UM-BBD_enzymeID:e0005
2003-10-27 Added XREF MetaCyc:ACETOACETYL-COA-REDUCTASE-RXN
2001-10-01 Added XREF EC:1.1.1.36
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