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GO:0017163 basal transcription repressor activity

This term is obsolete.
This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of your repressor is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.

Term Information

ID GO:0017163
Name basal transcription repressor activity
Ontology Molecular Function
Definition OBSOLETE. Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.
Comment This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of your repressor is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.
GONUTS GO:0017163 Wiki Page

Replaced by

This term is obsolete - try one of these terms:
Advice GO Identifier Ontology GO Term Name
Consider GO:0001078 Molecular Function RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
Consider GO:0001141 Molecular Function bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
Consider GO:0045892 Biological Process negative regulation of transcription, DNA-templated

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0017163:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0017163. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0017163 based on the entire annotation set Co-occurrence statistics for GO:0017163 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-05-16 Added OBSOLETION consider GO:0001078 (RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription)
2011-05-16 Added OBSOLETION consider GO:0001141 (bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription)
2011-05-16 Added OBSOLETION consider GO:0045892 (negative regulation of transcription, DNA-templated)
2011-05-16 Added DEFINITION OBSOLETE. Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.
2011-05-16 Deleted RELATION is a GO:0016564 (transcription repressor activity)
2011-05-16 Updated TERM basal transcription repressor activity
2011-05-16 Deleted DEFINITION Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.
2009-01-31 Added DEFINITION Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.
2009-01-31 Deleted DEFINITION Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.
2009-01-29 Updated TERM basal transcription repressor activity
2009-01-29 Added RELATION is a GO:0016564 (transcription repressor activity)
2009-01-29 Deleted RELATION is a GO:0030528 (transcription regulator activity)
2009-01-29 Added DEFINITION Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.
2008-04-01 Updated RELATION is a GO:0030528 (transcription regulator activity)
2003-03-19 Updated TERM negative regulator of basal transcription activity
2001-06-21 Added TERM negative regulator of basal transcription

Term

Timestamp Action Category Detail
2011-05-16 Updated TERM basal transcription repressor activity
2009-01-29 Updated TERM basal transcription repressor activity
2003-03-19 Updated TERM negative regulator of basal transcription activity
2001-06-21 Added TERM negative regulator of basal transcription

Obsoletions

Timestamp Action Category Detail
2011-05-16 Added OBSOLETION consider GO:0001078 (RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription)
2011-05-16 Added OBSOLETION consider GO:0001141 (bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription)
2011-05-16 Added OBSOLETION consider GO:0045892 (negative regulation of transcription, DNA-templated)

Definition/synonyms

Timestamp Action Category Detail
2011-05-16 Added DEFINITION OBSOLETE. Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.
2011-05-16 Deleted DEFINITION Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.
2009-01-31 Added DEFINITION Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.
2009-01-31 Deleted DEFINITION Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.
2009-01-29 Added DEFINITION Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.

Relationships

Timestamp Action Category Detail
2011-05-16 Deleted RELATION is a GO:0016564 (transcription repressor activity)
2009-01-29 Added RELATION is a GO:0016564 (transcription repressor activity)
2009-01-29 Deleted RELATION is a GO:0030528 (transcription regulator activity)
2008-04-01 Updated RELATION is a GO:0030528 (transcription regulator activity)
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