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GO:0017148 negative regulation of translation

Term Information

ID GO:0017148
Name negative regulation of translation
Ontology Biological Process
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
Secondary IDs GO:0016478
GONUTS GO:0017148 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact negative regulation of protein biosynthetic process
exact negative regulation of protein biosynthesis
exact negative regulation of protein formation
exact negative regulation of protein synthesis
related protein biosynthesis inhibitor activity
related protein biosynthetic process inhibitor activity
narrow inhibition of protein biosynthetic process
exact downregulation of protein biosynthetic process
exact down-regulation of protein biosynthetic process
exact down regulation of protein biosynthetic process
exact negative regulation of protein anabolism

Cross-references

Database ID
InterPro IPR001574
InterPro IPR004025
InterPro IPR016138
InterPro IPR016139
InterPro IPR016331
InterPro IPR017988
InterPro IPR029755
UniProtKB-KW Protein synthesis inhibitor

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0017149 protein biosynthetic process inhibitor activity REPLACEDBY GO:0017148

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0017148:
Relationship To GO:0017148 Child Term Child Term Name
Is a GO:0070130 negative regulation of mitochondrial translation
Part of GO:0030371 translation repressor activity
Is a GO:0007319 negative regulation of oskar mRNA translation
Is a GO:0032055 negative regulation of translation in response to stress
Is a GO:0040033 negative regulation of translation, ncRNA-mediated
Is a GO:0045900 negative regulation of translational elongation
Is a GO:0045902 negative regulation of translational fidelity
Is a GO:0045904 negative regulation of translational termination
Is a GO:0045947 negative regulation of translational initiation
Is a GO:0044074 negative regulation by symbiont of host translation
Is a GO:1902010 negative regulation of translation involved in response to endoplasmic reticulum stress
Is a GO:2000766 negative regulation of cytoplasmic translation

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0017148. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0017148 based on the entire annotation set Co-occurrence statistics for GO:0017148 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-10-18 Added RELATION is a GO:0010629 (negative regulation of gene expression)
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
2010-09-17 Added RELATION is a GO:2000113 (negative regulation of cellular macromolecule biosynthetic process)
2010-09-17 Deleted RELATION is a GO:0031327 (negative regulation of cellular biosynthetic process)
2010-09-17 Deleted RELATION is a GO:0010558 (negative regulation of macromolecule biosynthetic process)
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
2008-04-01 Deleted SYNONYM negative regulation of translation
2008-04-01 Updated RELATION is a GO:0031327 (negative regulation of cellular biosynthetic process)
2008-04-01 Updated RELATION is a GO:0032269 (negative regulation of cellular protein metabolic process)
2008-04-01 Updated RELATION is a GO:0010558 (negative regulation of macromolecule biosynthetic process)
2008-04-01 Added RELATION negatively regulates GO:0006412 (translation)
2008-04-01 Updated RELATION is a GO:0006417 (regulation of translation)
2007-11-16 Updated TERM negative regulation of translation
2007-11-16 Added SYNONYM negative regulation of protein biosynthetic process
2007-08-09 Added SYNONYM down regulation of protein biosynthetic process
2007-08-09 Added SYNONYM down-regulation of protein biosynthetic process
2007-08-09 Added SYNONYM downregulation of protein biosynthetic process
2007-08-09 Added SYNONYM inhibition of protein biosynthetic process
2007-08-09 Added SYNONYM negative regulation of protein anabolism
2007-08-09 Added SYNONYM negative regulation of protein biosynthesis
2007-08-09 Added SYNONYM negative regulation of protein formation
2007-08-09 Added SYNONYM negative regulation of protein synthesis
2007-08-09 Added SYNONYM negative regulation of translation
2007-08-09 Added SYNONYM protein biosynthesis inhibitor activity
2007-08-09 Added SYNONYM protein biosynthetic process inhibitor activity
2007-08-09 Deleted SYNONYM down regulation of protein biosynthetic process
2007-08-09 Deleted SYNONYM down-regulation of protein biosynthetic process
2007-08-09 Deleted SYNONYM downregulation of protein biosynthetic process
2007-08-09 Deleted SYNONYM inhibition of protein biosynthetic process
2007-08-09 Deleted SYNONYM protein biosynthetic process inhibitor activity
2007-08-09 Deleted SYNONYM negative regulation of protein biosynthesis
2007-08-09 Deleted SYNONYM negative regulation of translation
2007-08-09 Deleted SYNONYM negative regulation of protein anabolism
2007-08-09 Deleted SYNONYM negative regulation of protein formation
2007-08-09 Deleted SYNONYM negative regulation of protein synthesis
2007-08-09 Deleted SYNONYM protein biosynthesis inhibitor activity
2007-02-23 Added SYNONYM downregulation of protein biosynthetic process
2007-02-23 Added SYNONYM inhibition of protein biosynthetic process
2007-02-23 Added SYNONYM down regulation of protein biosynthetic process
2007-02-23 Added SYNONYM down-regulation of protein biosynthetic process
2007-01-15 Updated TERM negative regulation of protein biosynthetic process
2007-01-15 Added SYNONYM negative regulation of protein biosynthesis
2007-01-15 Added SYNONYM negative regulation of translation
2007-01-15 Added SYNONYM protein biosynthetic process inhibitor activity
2007-01-15 Added SECONDARY GO:0016478 (negative regulation of translation)
2007-01-09 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of proteins.
2005-08-10 Added SYNONYM negative regulation of protein anabolism
2005-08-10 Added SYNONYM negative regulation of protein formation
2005-08-10 Added SYNONYM negative regulation of protein synthesis
2005-08-10 Added SYNONYM protein biosynthesis inhibitor activity
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of the formation from simpler components of proteins.
2002-07-15 Updated TERM negative regulation of protein biosynthesis
2001-06-21 Added TERM protein biosynthesis inhibition

Term

Timestamp Action Category Detail
2007-11-16 Updated TERM negative regulation of translation
2007-01-15 Updated TERM negative regulation of protein biosynthetic process
2002-07-15 Updated TERM negative regulation of protein biosynthesis
2001-06-21 Added TERM protein biosynthesis inhibition

Definition/synonyms

Timestamp Action Category Detail
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
2008-04-01 Deleted SYNONYM negative regulation of translation
2007-11-16 Added SYNONYM negative regulation of protein biosynthetic process
2007-08-09 Added SYNONYM down regulation of protein biosynthetic process
2007-08-09 Added SYNONYM down-regulation of protein biosynthetic process
2007-08-09 Added SYNONYM downregulation of protein biosynthetic process
2007-08-09 Added SYNONYM inhibition of protein biosynthetic process
2007-08-09 Added SYNONYM negative regulation of protein anabolism
2007-08-09 Added SYNONYM negative regulation of protein biosynthesis
2007-08-09 Added SYNONYM negative regulation of protein formation
2007-08-09 Added SYNONYM negative regulation of protein synthesis
2007-08-09 Added SYNONYM negative regulation of translation
2007-08-09 Added SYNONYM protein biosynthesis inhibitor activity
2007-08-09 Added SYNONYM protein biosynthetic process inhibitor activity
2007-08-09 Deleted SYNONYM down regulation of protein biosynthetic process
2007-08-09 Deleted SYNONYM down-regulation of protein biosynthetic process
2007-08-09 Deleted SYNONYM downregulation of protein biosynthetic process
2007-08-09 Deleted SYNONYM inhibition of protein biosynthetic process
2007-08-09 Deleted SYNONYM protein biosynthetic process inhibitor activity
2007-08-09 Deleted SYNONYM negative regulation of protein biosynthesis
2007-08-09 Deleted SYNONYM negative regulation of translation
2007-08-09 Deleted SYNONYM negative regulation of protein anabolism
2007-08-09 Deleted SYNONYM negative regulation of protein formation
2007-08-09 Deleted SYNONYM negative regulation of protein synthesis
2007-08-09 Deleted SYNONYM protein biosynthesis inhibitor activity
2007-02-23 Added SYNONYM downregulation of protein biosynthetic process
2007-02-23 Added SYNONYM inhibition of protein biosynthetic process
2007-02-23 Added SYNONYM down regulation of protein biosynthetic process
2007-02-23 Added SYNONYM down-regulation of protein biosynthetic process
2007-01-15 Added SYNONYM negative regulation of protein biosynthesis
2007-01-15 Added SYNONYM negative regulation of translation
2007-01-15 Added SYNONYM protein biosynthetic process inhibitor activity
2007-01-09 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
2006-05-04 Updated DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins.
2005-10-21 Updated DEFINITION Any process that stops, prevents or reduces the rate, frequency or extent of the formation from simpler components of proteins.
2005-08-10 Added SYNONYM negative regulation of protein anabolism
2005-08-10 Added SYNONYM negative regulation of protein formation
2005-08-10 Added SYNONYM negative regulation of protein synthesis
2005-08-10 Added SYNONYM protein biosynthesis inhibitor activity
2002-11-27 Added DEFINITION Any process that stops, prevents or reduces the rate of the formation from simpler components of proteins.

Relationships

Timestamp Action Category Detail
2014-10-18 Added RELATION is a GO:0010629 (negative regulation of gene expression)
2010-09-17 Added RELATION is a GO:2000113 (negative regulation of cellular macromolecule biosynthetic process)
2010-09-17 Deleted RELATION is a GO:0031327 (negative regulation of cellular biosynthetic process)
2010-09-17 Deleted RELATION is a GO:0010558 (negative regulation of macromolecule biosynthetic process)
2008-04-01 Updated RELATION is a GO:0031327 (negative regulation of cellular biosynthetic process)
2008-04-01 Updated RELATION is a GO:0032269 (negative regulation of cellular protein metabolic process)
2008-04-01 Updated RELATION is a GO:0010558 (negative regulation of macromolecule biosynthetic process)
2008-04-01 Added RELATION negatively regulates GO:0006412 (translation)
2008-04-01 Updated RELATION is a GO:0006417 (regulation of translation)

Other

Timestamp Action Category Detail
2007-01-15 Added SECONDARY GO:0016478 (negative regulation of translation)
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