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GO:0017148 negative regulation of translation

Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.

Term Information

ID GO:0017148
Name negative regulation of translation
Ontology Biological Process
Definition Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
Comment

Synonyms

Type Synonym
exact negative regulation of protein biosynthetic process
exact negative regulation of protein biosynthesis
exact negative regulation of protein formation
exact negative regulation of protein synthesis
related protein biosynthesis inhibitor activity
related protein biosynthetic process inhibitor activity
narrow inhibition of protein biosynthetic process
exact downregulation of protein biosynthetic process
exact down-regulation of protein biosynthetic process
exact down regulation of protein biosynthetic process
exact negative regulation of protein anabolism

Cross-references associated with this term:

Database ID
INTERPRO IPR001574
INTERPRO IPR016138
INTERPRO IPR004025
INTERPRO IPR016331
INTERPRO IPR016139

This term can be used instead of these obsolete terms:

GO:0017149 protein biosynthetic process inhibitor activity (replaced_by GO:0017148)

Web service: term information

Use this URI template to access this data as a service:

GTerm?id=termID&format=format

Full details can be found on the QuickGO Web Services page.

Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.

Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0008150 biological_process
GO:0065007 biological regulation
GO:0008152 metabolic process
GO:0009987 cellular process
GO:0044238 primary metabolic process
GO:0050789 regulation of biological process
GO:0043170 macromolecule metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0043283 biopolymer metabolic process
GO:0010467 gene expression
GO:0048519 negative regulation of biological process
GO:0009059 macromolecule biosynthetic process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0044260 cellular macromolecule metabolic process
GO:0044249 cellular biosynthetic process
GO:0019538 protein metabolic process
GO:0080090 regulation of primary metabolic process
GO:0048523 negative regulation of cellular process
GO:0009892 negative regulation of metabolic process
GO:0060255 regulation of macromolecule metabolic process
GO:0009889 regulation of biosynthetic process
GO:0043284 biopolymer biosynthetic process
GO:0034960 cellular biopolymer metabolic process
GO:0031323 regulation of cellular metabolic process
GO:0010468 regulation of gene expression
GO:0010608 posttranscriptional regulation of gene expression
GO:0034645 cellular macromolecule biosynthetic process
GO:0010605 negative regulation of macromolecule metabolic process
GO:0009890 negative regulation of biosynthetic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0044267 cellular protein metabolic process
GO:0051246 regulation of protein metabolic process
GO:0031324 negative regulation of cellular metabolic process
GO:0031326 regulation of cellular biosynthetic process
GO:0034961 cellular biopolymer biosynthetic process
GO:0010558 negative regulation of macromolecule biosynthetic process
GO:0051248 negative regulation of protein metabolic process
GO:0006412 translation
GO:0031327 negative regulation of cellular biosynthetic process
GO:0032268 regulation of cellular protein metabolic process
GO:0032269 negative regulation of cellular protein metabolic process
GO:0006417 regulation of translation
GO:0017148 negative regulation of translation

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0070130 negative regulation of mitochondrial translation
I GO:0007319 negative regulation of oskar mRNA translation
I GO:0032055 negative regulation of translation in response to stress
I GO:0040033 negative regulation of translation, ncRNA-mediated
I GO:0045900 negative regulation of translational elongation
I GO:0045902 negative regulation of translational fidelity
I GO:0045904 negative regulation of translational termination
I GO:0045947 negative regulation of translational initiation
I GO:0044074 negative regulation by symbiont of host translation

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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