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GO:0017065 single-strand selective uracil DNA N-glycosylase activity

Term Information

ID GO:0017065
Name single-strand selective uracil DNA N-glycosylase activity
Ontology Molecular Function
Definition Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
PMID:9224623
GONUTS GO:0017065 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact single-strand selective monofunctional uracil-DNA glycosylase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.2.2.-

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0017065:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0017065. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0017065 based on the entire annotation set Co-occurrence statistics for GO:0017065 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
2008-05-12 Deleted DEFINITION Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
2008-04-01 Updated RELATION is a GO:0004844 (uracil DNA N-glycosylase activity)
2007-11-08 Deleted SYNONYM single-strand selective monofunctional uracil-DNA glycosylase
2007-11-08 Added SYNONYM single-strand selective monofunctional uracil-DNA glycosylase activity
2007-08-09 Added SYNONYM single-strand selective monofunctional uracil-DNA glycosylase
2007-08-09 Deleted SYNONYM single-strand selective monofunctional uracil-DNA glycosylase
2004-04-19 Added SYNONYM single-strand selective monofunctional uracil-DNA glycosylase
2004-04-16 Deleted SYNONYM single-strand selective monofunctional uracil-DNA glycosylase
2003-08-05 Updated DEFINITION Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
2003-03-19 Updated TERM single-strand selective uracil DNA N-glycosylase activity
2002-11-27 Added DEFINITION Recognizes and removes uracil bases present in single-stranded DNA. The reaction cleaves the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site.
2002-05-17 Added SYNONYM single-strand selective monofunctional uracil-DNA glycosylase
2002-05-17 Updated TERM single-strand selective uracil DNA N-glycosylase
2001-05-16 Added XREF EC:3.2.2.-
2001-05-16 Added TERM single-strand selective monofunctional uracil-DNA glycosylase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM single-strand selective uracil DNA N-glycosylase activity
2002-05-17 Updated TERM single-strand selective uracil DNA N-glycosylase
2001-05-16 Added TERM single-strand selective monofunctional uracil-DNA glycosylase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
2008-05-12 Deleted DEFINITION Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
2007-11-08 Deleted SYNONYM single-strand selective monofunctional uracil-DNA glycosylase
2007-11-08 Added SYNONYM single-strand selective monofunctional uracil-DNA glycosylase activity
2007-08-09 Added SYNONYM single-strand selective monofunctional uracil-DNA glycosylase
2007-08-09 Deleted SYNONYM single-strand selective monofunctional uracil-DNA glycosylase
2004-04-19 Added SYNONYM single-strand selective monofunctional uracil-DNA glycosylase
2004-04-16 Deleted SYNONYM single-strand selective monofunctional uracil-DNA glycosylase
2003-08-05 Updated DEFINITION Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
2002-11-27 Added DEFINITION Recognizes and removes uracil bases present in single-stranded DNA. The reaction cleaves the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site.
2002-05-17 Added SYNONYM single-strand selective monofunctional uracil-DNA glycosylase

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004844 (uracil DNA N-glycosylase activity)

Cross-references

Timestamp Action Category Detail
2001-05-16 Added XREF EC:3.2.2.-
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