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GO:0046353 aminoglycoside 3-N-acetyltransferase activity

Term Information

ID GO:0046353
Name aminoglycoside 3-N-acetyltransferase activity
Ontology Molecular Function
Definition Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring.
Secondary IDs GO:0016991
GONUTS GO:0046353 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow acetyl-CoA:gentamicin-C N3'-acetyltransferase activity
narrow gentamicin-(3)-N-acetyltransferase activity
narrow gentamicin 3'-N-acetyltransferase activity
related aminoglycoside acetyltransferase AAC(3)-I activity
related aminoglycoside acetyltransferase AAC(3)-1
related 3'-aminoglycoside acetyltransferase activity
related gentamycin acetyltransferase I
exact gentamycin 3'-N-acetyltransferase activity
narrow gentamicin acetyltransferase I activity
exact acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase activity
exact 3-N-aminoglycoside acetyltransferase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.3.1.60
EC 2.3.1.81
InterPro IPR003679
MetaCyc AMINOGLYCOSIDE-N3-ACETYLTRANSFERASE-RXN
MetaCyc GENTAMICIN-3-N-ACETYLTRANSFERASE-RXN

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0046353:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0046353. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0046353 based on the entire annotation set Co-occurrence statistics for GO:0046353 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2009-05-21 Deleted XREF MetaCyc:AMINOGLYCOSIDE-N3'-ACETYLTRANSFERASE-RXN
2009-05-21 Deleted XREF MetaCyc:GENTAMICIN-3'-N-ACETYLTRANSFERASE-RXN
2009-05-21 Added XREF MetaCyc:GENTAMICIN-3-N-ACETYLTRANSFERASE-RXN
2009-05-21 Added XREF MetaCyc:AMINOGLYCOSIDE-N3-ACETYLTRANSFERASE-RXN
2008-05-13 Added DEFINITION Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring.
2008-04-01 Updated RELATION is a GO:0034069 (aminoglycoside N-acetyltransferase activity)
2008-01-27 Updated DEFINITION Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring.
2008-01-10 Added SECONDARY GO:0016991 (gentamicin 3'-N-acetyltransferase activity)
2008-01-10 Added XREF MetaCyc:GENTAMICIN-3'-N-ACETYLTRANSFERASE-RXN
2008-01-10 Added XREF EC:2.3.1.60
2008-01-10 Added SYNONYM 3'-aminoglycoside acetyltransferase activity
2008-01-10 Added SYNONYM acetyl-CoA:gentamicin-C N3'-acetyltransferase activity
2008-01-10 Added SYNONYM aminoglycoside acetyltransferase AAC(3)-1
2008-01-10 Added SYNONYM aminoglycoside acetyltransferase AAC(3)-I activity
2008-01-10 Added SYNONYM gentamicin 3'-N-acetyltransferase activity
2008-01-10 Added SYNONYM gentamicin acetyltransferase I activity
2008-01-10 Added SYNONYM gentamycin 3'-N-acetyltransferase activity
2008-01-10 Added SYNONYM gentamycin acetyltransferase I
2008-01-10 Deleted SYNONYM 3'-aminoglycoside acetyltransferase activity
2008-01-10 Updated TERM aminoglycoside 3-N-acetyltransferase activity
2007-11-08 Added SYNONYM 3'-aminoglycoside acetyltransferase activity
2007-11-08 Added SYNONYM 3-N-aminoglycoside acetyltransferase activity
2007-11-08 Added SYNONYM acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase activity
2007-09-06 Added SYNONYM gentamicin-(3)-N-acetyltransferase activity
2006-01-26 Updated DEFINITION Catalysis of the reaction: acetyl-CoA + a 2-deoxystreptamine antibiotic = CoA + N3'-acetyl-2-deoxystreptamine antibiotic.
2003-10-27 Added XREF MetaCyc:AMINOGLYCOSIDE-N3'-ACETYLTRANSFERASE-RXN
2003-03-19 Updated TERM aminoglycoside N3'-acetyltransferase activity
2002-11-27 Added DEFINITION Catalysis of the reaction:acetyl-CoA + a 2-deoxystreptamine antibiotic = CoA + N3'-acetyl-2-deoxystreptamine antibiotic.
2002-09-17 Added XREF EC:2.3.1.81
2002-09-17 Added TERM aminoglycoside N3'-acetyltransferase

Term

Timestamp Action Category Detail
2008-01-10 Updated TERM aminoglycoside 3-N-acetyltransferase activity
2003-03-19 Updated TERM aminoglycoside N3'-acetyltransferase activity
2002-09-17 Added TERM aminoglycoside N3'-acetyltransferase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring.
2008-01-27 Updated DEFINITION Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring.
2008-01-10 Added SYNONYM 3'-aminoglycoside acetyltransferase activity
2008-01-10 Added SYNONYM acetyl-CoA:gentamicin-C N3'-acetyltransferase activity
2008-01-10 Added SYNONYM aminoglycoside acetyltransferase AAC(3)-1
2008-01-10 Added SYNONYM aminoglycoside acetyltransferase AAC(3)-I activity
2008-01-10 Added SYNONYM gentamicin 3'-N-acetyltransferase activity
2008-01-10 Added SYNONYM gentamicin acetyltransferase I activity
2008-01-10 Added SYNONYM gentamycin 3'-N-acetyltransferase activity
2008-01-10 Added SYNONYM gentamycin acetyltransferase I
2008-01-10 Deleted SYNONYM 3'-aminoglycoside acetyltransferase activity
2007-11-08 Added SYNONYM 3'-aminoglycoside acetyltransferase activity
2007-11-08 Added SYNONYM 3-N-aminoglycoside acetyltransferase activity
2007-11-08 Added SYNONYM acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase activity
2007-09-06 Added SYNONYM gentamicin-(3)-N-acetyltransferase activity
2006-01-26 Updated DEFINITION Catalysis of the reaction: acetyl-CoA + a 2-deoxystreptamine antibiotic = CoA + N3'-acetyl-2-deoxystreptamine antibiotic.
2002-11-27 Added DEFINITION Catalysis of the reaction:acetyl-CoA + a 2-deoxystreptamine antibiotic = CoA + N3'-acetyl-2-deoxystreptamine antibiotic.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0034069 (aminoglycoside N-acetyltransferase activity)

Cross-references

Timestamp Action Category Detail
2009-05-21 Deleted XREF MetaCyc:AMINOGLYCOSIDE-N3'-ACETYLTRANSFERASE-RXN
2009-05-21 Deleted XREF MetaCyc:GENTAMICIN-3'-N-ACETYLTRANSFERASE-RXN
2009-05-21 Added XREF MetaCyc:GENTAMICIN-3-N-ACETYLTRANSFERASE-RXN
2009-05-21 Added XREF MetaCyc:AMINOGLYCOSIDE-N3-ACETYLTRANSFERASE-RXN
2008-01-10 Added XREF MetaCyc:GENTAMICIN-3'-N-ACETYLTRANSFERASE-RXN
2008-01-10 Added XREF EC:2.3.1.60
2003-10-27 Added XREF MetaCyc:AMINOGLYCOSIDE-N3'-ACETYLTRANSFERASE-RXN
2002-09-17 Added XREF EC:2.3.1.81

Other

Timestamp Action Category Detail
2008-01-10 Added SECONDARY GO:0016991 (gentamicin 3'-N-acetyltransferase activity)
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