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GO:0016921 pyroglutamyl-peptidase II activity

This term is obsolete.
This term was made obsolete because it represents a gene product.

Term Information

ID GO:0016921
Name pyroglutamyl-peptidase II activity
Ontology Molecular Function
Definition OBSOLETE. Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.
Comment This term was made obsolete because it represents a gene product.
GONUTS GO:0016921 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related pyroglutamyl peptidase II
narrow thyroliberinase activity
exact pyroglutamyl aminopeptidase II activity
narrow TRH-specific aminopeptidase activity
narrow TRH-degrading ectoenzyme activity
narrow TRH-DE activity
exact PAP-II activity
exact thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase activity
exact thyrotropin-releasing hormone-degrading peptidase activity
exact thyrotropin-releasing factor pyroglutamate aminopeptidase activity
related pyroglutamate aminopeptidase II
narrow thyrotropin-releasing hormone degrading ectoenzyme activity
exact thyroliberin-hydrolyzing pyroglutamate aminopeptidase activity

Replaced by

This term is obsolete - try one of these terms:
Advice GO Identifier Ontology GO Term Name
Replaced by GO:0008237 Molecular Function metallopeptidase activity
Replaced by GO:0016920 Molecular Function pyroglutamyl-peptidase activity

Cross-references

Database ID
EC 3.4.19.6
MetaCyc 3.4.19.6-RXN

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016921:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016921. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016921 based on the entire annotation set Co-occurrence statistics for GO:0016921 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2010-06-08 Updated TERM pyroglutamyl-peptidase II activity
2008-11-08 Added OBSOLETION replaced_by GO:0008237 (metallopeptidase activity)
2008-11-08 Added OBSOLETION replaced_by GO:0016920 (pyroglutamyl-peptidase activity)
2008-10-21 Deleted OBSOLETION replaced_by GO:0008237 (metallopeptidase activity)
2008-10-21 Deleted OBSOLETION replaced_by GO:0016920 (pyroglutamyl-peptidase activity)
2008-08-18 Added OBSOLETION replaced_by GO:0016920 (pyroglutamyl-peptidase activity)
2008-08-18 Added OBSOLETION replaced_by GO:0008237 (metallopeptidase activity)
2008-08-18 Deleted RELATION is a GO:0016920 (pyroglutamyl-peptidase activity)
2008-08-18 Deleted RELATION is a GO:0008237 (metallopeptidase activity)
2008-08-18 Added RELATION is a GO:0008369 (obsolete molecular function)
2008-08-18 Deleted DEFINITION Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.
2008-08-18 Added DEFINITION OBSOLETE. Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.
2008-05-13 Added DEFINITION Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.
2008-05-12 Deleted DEFINITION Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.
2008-04-01 Updated RELATION is a GO:0016920 (pyroglutamyl-peptidase activity)
2008-04-01 Updated RELATION is a GO:0008237 (metallopeptidase activity)
2007-11-08 Added SYNONYM pyroglutamate aminopeptidase II
2007-11-08 Added SYNONYM pyroglutamyl peptidase II
2007-11-08 Added SYNONYM thyroliberin-hydrolyzing pyroglutamate aminopeptidase activity
2007-11-08 Added SYNONYM thyrotropin-releasing factor pyroglutamate aminopeptidase activity
2007-11-08 Added SYNONYM thyrotropin-releasing hormone-degrading peptidase activity
2007-11-08 Added SYNONYM thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase activity
2007-09-06 Added SYNONYM PAP-II activity
2007-09-06 Added SYNONYM TRH-DE activity
2007-09-06 Added SYNONYM TRH-degrading ectoenzyme activity
2007-09-06 Added SYNONYM TRH-specific aminopeptidase activity
2007-09-06 Added SYNONYM pyroglutamyl aminopeptidase II activity
2007-09-06 Added SYNONYM thyroliberinase activity
2007-09-06 Added SYNONYM thyrotropin-releasing hormone degrading ectoenzyme activity
2003-10-27 Added XREF MetaCyc:3.4.19.6-RXN
2003-03-19 Updated TERM pyroglutamyl-peptidase II activity
2002-11-27 Added DEFINITION Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.
2002-02-06 Updated TERM pyroglutamyl-peptidase II
2001-04-03 Updated TERM pyroglutamyl-peptidase II
2001-03-30 Added XREF EC:3.4.19.6
2001-03-30 Added TERM pyroglutamyl-peptidase II

Term

Timestamp Action Category Detail
2010-06-08 Updated TERM pyroglutamyl-peptidase II activity
2003-03-19 Updated TERM pyroglutamyl-peptidase II activity
2002-02-06 Updated TERM pyroglutamyl-peptidase II
2001-04-03 Updated TERM pyroglutamyl-peptidase II
2001-03-30 Added TERM pyroglutamyl-peptidase II

Obsoletions

Timestamp Action Category Detail
2008-11-08 Added OBSOLETION replaced_by GO:0008237 (metallopeptidase activity)
2008-11-08 Added OBSOLETION replaced_by GO:0016920 (pyroglutamyl-peptidase activity)
2008-10-21 Deleted OBSOLETION replaced_by GO:0008237 (metallopeptidase activity)
2008-10-21 Deleted OBSOLETION replaced_by GO:0016920 (pyroglutamyl-peptidase activity)
2008-08-18 Added OBSOLETION replaced_by GO:0016920 (pyroglutamyl-peptidase activity)
2008-08-18 Added OBSOLETION replaced_by GO:0008237 (metallopeptidase activity)

Definition/synonyms

Timestamp Action Category Detail
2008-08-18 Deleted DEFINITION Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.
2008-08-18 Added DEFINITION OBSOLETE. Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.
2008-05-13 Added DEFINITION Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.
2008-05-12 Deleted DEFINITION Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.
2007-11-08 Added SYNONYM pyroglutamate aminopeptidase II
2007-11-08 Added SYNONYM pyroglutamyl peptidase II
2007-11-08 Added SYNONYM thyroliberin-hydrolyzing pyroglutamate aminopeptidase activity
2007-11-08 Added SYNONYM thyrotropin-releasing factor pyroglutamate aminopeptidase activity
2007-11-08 Added SYNONYM thyrotropin-releasing hormone-degrading peptidase activity
2007-11-08 Added SYNONYM thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase activity
2007-09-06 Added SYNONYM PAP-II activity
2007-09-06 Added SYNONYM TRH-DE activity
2007-09-06 Added SYNONYM TRH-degrading ectoenzyme activity
2007-09-06 Added SYNONYM TRH-specific aminopeptidase activity
2007-09-06 Added SYNONYM pyroglutamyl aminopeptidase II activity
2007-09-06 Added SYNONYM thyroliberinase activity
2007-09-06 Added SYNONYM thyrotropin-releasing hormone degrading ectoenzyme activity
2002-11-27 Added DEFINITION Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.

Relationships

Timestamp Action Category Detail
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2008-08-18 Deleted RELATION is a GO:0016920 (pyroglutamyl-peptidase activity)
2008-08-18 Deleted RELATION is a GO:0008237 (metallopeptidase activity)
2008-08-18 Added RELATION is a GO:0008369 (obsolete molecular function)
2008-04-01 Updated RELATION is a GO:0016920 (pyroglutamyl-peptidase activity)
2008-04-01 Updated RELATION is a GO:0008237 (metallopeptidase activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:3.4.19.6-RXN
2001-03-30 Added XREF EC:3.4.19.6
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