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GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

Term Information

ID GO:0016893
Name endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
Ontology Molecular Function
Definition Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
Comment Note that this activity can catalyze cleavage of DNA or RNA.
GONUTS GO:0016893 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
exact 5'-endonuclease activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.1.30

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016893:
Relationship To GO:0016893 Child Term Child Term Name
Is a GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters
Is a GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters

Protein Annotation

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GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016893. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016893 based on the entire annotation set Co-occurrence statistics for GO:0016893 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
2008-04-01 Updated RELATION is a GO:0004519 (endonuclease activity)
2007-08-09 Added SYNONYM 5'-endonuclease activity
2007-08-09 Added SYNONYM endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2007-08-09 Deleted SYNONYM 5'-endonuclease activity
2007-08-09 Deleted SYNONYM endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2006-02-09 Added XREF EC:3.1.30
2006-02-09 Deleted XREF EC:3.1.30.-
2004-04-19 Added SYNONYM 5'-endonuclease activity
2004-04-19 Added SYNONYM endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2004-04-05 Deleted SYNONYM endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2003-07-23 Updated TERM endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2003-07-23 Added DEFINITION Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
2003-07-23 Added SYNONYM endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2003-03-25 Updated TERM endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2003-03-19 Updated TERM endoribonuclease, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters activity
2002-02-06 Updated TERM endoribonuclease, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2001-04-03 Updated TERM endoribonuclease, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2001-03-30 Added XREF EC:3.1.30.-
2001-03-30 Added TERM endoribonuclease, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

Term

Timestamp Action Category Detail
2003-07-23 Updated TERM endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2003-03-25 Updated TERM endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2003-03-19 Updated TERM endoribonuclease, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters activity
2002-02-06 Updated TERM endoribonuclease, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2001-04-03 Updated TERM endoribonuclease, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2001-03-30 Added TERM endoribonuclease, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
2008-05-12 Deleted DEFINITION Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
2007-08-09 Added SYNONYM 5'-endonuclease activity
2007-08-09 Added SYNONYM endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2007-08-09 Deleted SYNONYM 5'-endonuclease activity
2007-08-09 Deleted SYNONYM endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2004-04-19 Added SYNONYM 5'-endonuclease activity
2004-04-19 Added SYNONYM endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2004-04-05 Deleted SYNONYM endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
2003-07-23 Added DEFINITION Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
2003-07-23 Added SYNONYM endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0004519 (endonuclease activity)

Cross-references

Timestamp Action Category Detail
2006-02-09 Added XREF EC:3.1.30
2006-02-09 Deleted XREF EC:3.1.30.-
2001-03-30 Added XREF EC:3.1.30.-
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