spacer
spacer

GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor

Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases catalyze two separate reactions at two active sites, which are located either on a single polypeptide chain or on different subunits. In the glutaminase reaction, glutamine is hydrolyzed to glutamate and ammonia, which is added to an acceptor substrate in the synthase reaction.

Term Information

ID GO:0016884
Name carbon-nitrogen ligase activity, with glutamine as amido-N-donor
Ontology Molecular Function
Definition Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases catalyze two separate reactions at two active sites, which are located either on a single polypeptide chain or on different subunits. In the glutaminase reaction, glutamine is hydrolyzed to glutamate and ammonia, which is added to an acceptor substrate in the synthase reaction.
Comment

Cross-references associated with this term:

Database ID
EC 6.3.5
INTERPRO IPR018027
INTERPRO IPR004414
INTERPRO IPR004413
INTERPRO IPR003789
INTERPRO IPR017958
INTERPRO IPR017959
INTERPRO IPR000120
INTERPRO IPR006107

Web service: term information

Use this URI template to access this data as a service:

GTerm?id=termID&format=format

Full details can be found on the QuickGO Web Services page.

Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.

Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016874 ligase activity
GO:0016879 ligase activity, forming carbon-nitrogen bonds
GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0003922 GMP synthase (glutamine-hydrolyzing) activity
I GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
I GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity
I GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
I GO:0050566 asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
I GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
I GO:0004642 phosphoribosylformylglycinamidine synthase activity
I GO:0051921 adenosylcobyric acid synthase (glutamine-hydrolyzing) activity
I GO:0043775 cobyrinate a,c-diamide synthase activity
I GO:0043802 hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
spacer
12ms
spacer