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GO:0016881 acid-amino acid ligase activity

Term Information

ID GO:0016881
Name acid-amino acid ligase activity
Ontology Molecular Function
Definition Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GONUTS GO:0016881 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact peptide synthase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 6.3.2
InterPro IPR000608
InterPro IPR005757
InterPro IPR005761
InterPro IPR014929
InterPro IPR015036
InterPro IPR016398
InterPro IPR017335
InterPro IPR019485
InterPro IPR019943
InterPro IPR023318

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016881:
Relationship To GO:0016881 Child Term Child Term Name
Is a GO:0051108 carnitine-CoA ligase activity
Is a GO:0047914 gamma-glutamylhistamine synthase activity
Is a GO:0047527 2,3-dihydroxybenzoate-serine ligase activity
Is a GO:0047983 homoglutathione synthase activity
Is a GO:0004326 tetrahydrofolylpolyglutamate synthase activity
Is a GO:0004357 glutamate-cysteine ligase activity
Is a GO:0004363 glutathione synthase activity
Is a GO:0050367 tyrosine-arginine ligase activity
Is a GO:0047480 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Is a GO:0047481 D-alanine-alanyl-poly(glycerolphosphate) ligase activity
Is a GO:0047482 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity
Is a GO:0050564 N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity
Is a GO:0050565 aerobactin synthase activity
Is a GO:0008716 D-alanine-D-alanine ligase activity
Is a GO:0008763 UDP-N-acetylmuramate-L-alanine ligase activity
Is a GO:0008764 UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
Is a GO:0008765 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity
Is a GO:0008766 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
Is a GO:0008841 dihydrofolate synthase activity
Is a GO:0004592 pantoate-beta-alanine ligase activity
Is a GO:0047730 carnosine synthase activity
Is a GO:0018814 phenylacetaldoxime dehydratase activity
Is a GO:0004632 phosphopantothenate--cysteine ligase activity
Is a GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Is a GO:0004835 tubulin-tyrosine ligase activity
Is a GO:0019787 small conjugating protein ligase activity
Is a GO:0043860 cyanophycin synthetase activity
Is a GO:0043773 coenzyme F420-0 gamma-glutamyl ligase activity
Is a GO:0043774 coenzyme F420-2 alpha-glutamyl ligase activity
Is a GO:0080123 jasmonate-amino synthetase activity
Is a GO:0052618 coenzyme F420-0:L-glutamate ligase activity
Is a GO:0052619 coenzyme F420-1:gamma-L-glutamate ligase activity
Is a GO:0052625 4-aminobenzoate amino acid synthetase activity
Is a GO:0052626 benzoate amino acid synthetase activity
Is a GO:0052627 vanillate amino acid synthetase activity
Is a GO:0052628 4-hydroxybenzoate amino acid synthetase activity
Is a GO:0010279 indole-3-acetic acid amido synthetase activity
Is a GO:0034013 aliphatic aldoxime dehydratase activity
Is a GO:0034026 L-amino-acid alpha-ligase activity
Is a GO:0097429 amino acid ligation activity by nonribosomal peptide synthase
Is a GO:0070735 protein-glycine ligase activity
Is a GO:0070739 protein-glutamic acid ligase activity
Is a GO:0017178 diphthine-ammonia ligase activity

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016881. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016881 based on the entire annotation set Co-occurrence statistics for GO:0016881 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-24 Deleted DEFINITION Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2010-10-24 Added DEFINITION Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
2008-05-13 Added DEFINITION Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2008-04-01 Updated RELATION is a GO:0016879 (ligase activity, forming carbon-nitrogen bonds)
2007-11-08 Deleted SYNONYM peptide synthase
2007-11-08 Added SYNONYM peptide synthase activity
2007-08-09 Added SYNONYM peptide synthase
2007-08-09 Deleted SYNONYM peptide synthase
2007-06-27 Added DEFINITION Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2006-02-09 Added XREF EC:6.3.2
2006-02-09 Deleted XREF EC:6.3.2.-
2005-02-12 Updated TERM acid-amino acid ligase activity
2004-04-19 Added SYNONYM peptide synthase
2004-04-16 Deleted SYNONYM peptide synthase
2003-03-19 Updated TERM acid-D-amino acid ligase activity
2002-02-06 Updated TERM acid-D-amino acid ligase
2001-04-03 Updated TERM acid-D-amino acid ligase
2001-03-30 Added XREF EC:6.3.2.-
2001-03-30 Added SYNONYM peptide synthase
2001-03-30 Added TERM acid-D-amino acid ligase

Term

Timestamp Action Category Detail
2005-02-12 Updated TERM acid-amino acid ligase activity
2003-03-19 Updated TERM acid-D-amino acid ligase activity
2002-02-06 Updated TERM acid-D-amino acid ligase
2001-04-03 Updated TERM acid-D-amino acid ligase
2001-03-30 Added TERM acid-D-amino acid ligase

Definition/synonyms

Timestamp Action Category Detail
2010-10-24 Deleted DEFINITION Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2010-10-24 Added DEFINITION Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
2008-05-13 Added DEFINITION Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2007-11-08 Deleted SYNONYM peptide synthase
2007-11-08 Added SYNONYM peptide synthase activity
2007-08-09 Added SYNONYM peptide synthase
2007-08-09 Deleted SYNONYM peptide synthase
2007-06-27 Added DEFINITION Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2004-04-19 Added SYNONYM peptide synthase
2004-04-16 Deleted SYNONYM peptide synthase
2001-03-30 Added SYNONYM peptide synthase

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016879 (ligase activity, forming carbon-nitrogen bonds)

Cross-references

Timestamp Action Category Detail
2006-02-09 Added XREF EC:6.3.2
2006-02-09 Deleted XREF EC:6.3.2.-
2001-03-30 Added XREF EC:6.3.2.-
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