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GO:0016878 acid-thiol ligase activity

Term Information

ID GO:0016878
Name acid-thiol ligase activity
Ontology Molecular Function
Definition Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
GONUTS GO:0016878 Wiki Page

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 6.2.1
InterPro IPR011957
InterPro IPR023456

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016878:
Relationship To GO:0016878 Child Term Child Term Name
Is a GO:0043955 3-hydroxypropionyl-CoA synthetase activity
Is a GO:0047851 dicarboxylate-CoA ligase activity
Is a GO:0047541 2-furoate-CoA ligase activity
Is a GO:0008922 long-chain fatty acid [acyl-carrier-protein] ligase activity
Is a GO:0047948 glutarate-CoA ligase activity
Is a GO:0050074 malate-CoA ligase activity
Is a GO:0047612 acid-CoA ligase (GDP-forming) activity
Is a GO:0050197 phytanate-CoA ligase activity
Is a GO:0050203 oxalate-CoA ligase activity
Is a GO:0050218 propionate-CoA ligase activity
Is a GO:0030729 acetoacetate-CoA ligase activity
Is a GO:0003987 acetate-CoA ligase activity
Is a GO:0003996 acyl-CoA ligase activity
Is a GO:0004774 succinate-CoA ligase activity
Is a GO:0008756 o-succinylbenzoate-CoA ligase activity
Is a GO:0008771 [citrate (pro-3S)-lyase] ligase activity
Is a GO:0016207 4-coumarate-CoA ligase activity
Is a GO:0018854 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity
Is a GO:0018855 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity
Is a GO:0018856 benzoyl acetate-CoA ligase activity
Is a GO:0018857 2,4-dichlorobenzoate-CoA ligase activity
Is a GO:0018858 benzoate-CoA ligase activity
Is a GO:0018859 4-hydroxybenzoate-CoA ligase activity
Is a GO:0018860 anthranilate-CoA ligase activity
Is a GO:0018861 4-chlorobenzoate-CoA ligase activity
Is a GO:0047474 long-chain fatty acid luciferin component ligase activity
Is a GO:0047475 phenylacetate-CoA ligase activity
Is a GO:0047476 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity
Is a GO:0050563 trans-feruloyl-CoA synthase activity
Is a GO:0042410 6-carboxyhexanoate-CoA ligase activity
Is a GO:0047676 arachidonate-CoA ligase activity
Is a GO:0047707 biotin-CoA ligase activity
Is a GO:0047747 cholate-CoA ligase activity
Is a GO:0047760 butyrate-CoA ligase activity
Is a GO:0047779 citrate-CoA ligase activity
Is a GO:0043758 acetate-CoA ligase (ADP-forming) activity
Is a GO:0043759 branched-chain acyl-CoA synthetase (ADP-forming) activity
Is a GO:0034942 cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
Is a GO:0034943 trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity
Is a GO:0070251 pristanate-CoA ligase activity
Is a GO:0043762 aryl-CoA synthetase (ADP-forming) activity
Is a GO:0034783 pivalate-CoA ligase activity
Is a GO:0034793 cyclopropanecarboxylate-CoA ligase activity
Is a GO:0034796 adipate-CoA ligase activity
Is a GO:0034823 citronellyl-CoA ligase activity
Is a GO:0034841 mentha-1,3-dione-CoA ligase activity
Is a GO:0034842 thiophene-2-carboxylate-CoA ligase activity
Is a GO:0034865 2,4,4-trimethylpentanoate-CoA ligase activity
Is a GO:0090409 malonyl-CoA synthetase activity
Is a GO:0052685 perillic acid:CoA ligase (ADP-forming) activity
Is a GO:0052686 perillic acid:CoA ligase (AMP-forming) activity
Is a GO:0052687 (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity
Is a GO:0052688 (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016878. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016878 based on the entire annotation set Co-occurrence statistics for GO:0016878 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-10-24 Deleted DEFINITION Catalysis of the ligation of an acid and a thiol via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2010-10-24 Added DEFINITION Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
2008-05-13 Added DEFINITION Catalysis of the ligation of an acid and a thiol via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the ligation of an acid and a thiol via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2008-04-01 Updated RELATION is a GO:0016877 (ligase activity, forming carbon-sulfur bonds)
2007-06-27 Added DEFINITION Catalysis of the ligation of an acid and a thiol via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2006-02-09 Added XREF EC:6.2.1
2006-02-09 Deleted XREF EC:6.2.1.-
2003-03-19 Updated TERM acid-thiol ligase activity
2002-02-06 Updated TERM acid-thiol ligase
2001-04-03 Updated TERM acid-thiol ligase
2001-03-30 Added XREF EC:6.2.1.-
2001-03-30 Added TERM acid-thiol ligase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM acid-thiol ligase activity
2002-02-06 Updated TERM acid-thiol ligase
2001-04-03 Updated TERM acid-thiol ligase
2001-03-30 Added TERM acid-thiol ligase

Definition/synonyms

Timestamp Action Category Detail
2010-10-24 Deleted DEFINITION Catalysis of the ligation of an acid and a thiol via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2010-10-24 Added DEFINITION Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
2008-05-13 Added DEFINITION Catalysis of the ligation of an acid and a thiol via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the ligation of an acid and a thiol via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
2007-06-27 Added DEFINITION Catalysis of the ligation of an acid and a thiol via a carbon-sulfur bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016877 (ligase activity, forming carbon-sulfur bonds)

Cross-references

Timestamp Action Category Detail
2006-02-09 Added XREF EC:6.2.1
2006-02-09 Deleted XREF EC:6.2.1.-
2001-03-30 Added XREF EC:6.2.1.-
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