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GO:0016854 racemase and epimerase activity

Term Information

ID GO:0016854
Name racemase and epimerase activity
Ontology Molecular Function
Definition Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.
Comment Note that enzymes of class EC:5.1.99.- should also be annotated to this term. Note that 'epimerase' refers to the conversion of an epimer into its diastereoisomer, and 'racemase' refers to the interconversion of the two enantiomers of a chiral compound.
GONUTS GO:0016854 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow racemase and epimerase activity, acting on other compounds

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 5.1
InterPro IPR023751

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0016858 racemase and epimerase activity, acting on other compounds CONSIDER GO:0016854

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016854:
Relationship To GO:0016854 Child Term Child Term Name
Is a GO:0004493 methylmalonyl-CoA epimerase activity
Is a GO:0008111 alpha-methylacyl-CoA racemase activity
Is a GO:0047524 16-hydroxysteroid epimerase activity
Is a GO:0047653 allantoin racemase activity
Is a GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives
Is a GO:0016856 racemase and epimerase activity, acting on hydroxy acids and derivatives
Is a GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives
Is a GO:0052856 NADHX epimerase activity
Is a GO:0052857 NADPHX epimerase activity
Is a GO:0036348 hydantoin racemase activity

Protein Annotation

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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016854. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016854 based on the entire annotation set Co-occurrence statistics for GO:0016854 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.
2008-05-12 Deleted DEFINITION Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.
2008-04-01 Updated RELATION is a GO:0016853 (isomerase activity)
2007-08-09 Added SYNONYM racemase and epimerase activity, acting on other compounds
2007-08-09 Deleted SYNONYM racemase and epimerase activity, acting on other compounds
2006-02-09 Added XREF EC:5.1
2006-02-09 Deleted XREF EC:5.1.-.-
2005-08-10 Added SYNONYM racemase and epimerase activity, acting on other compounds
2005-05-19 Added DEFINITION Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.
2003-03-19 Updated TERM racemase and epimerase activity
2002-02-06 Updated TERM racemase and epimerase
2001-10-03 Updated TERM racemase and epimerase
2001-04-03 Updated TERM racemases and epimerase
2001-03-30 Added XREF EC:5.1.-.-
2001-03-30 Added TERM racemases and epimerase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM racemase and epimerase activity
2002-02-06 Updated TERM racemase and epimerase
2001-10-03 Updated TERM racemase and epimerase
2001-04-03 Updated TERM racemases and epimerase
2001-03-30 Added TERM racemases and epimerase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.
2008-05-12 Deleted DEFINITION Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.
2007-08-09 Added SYNONYM racemase and epimerase activity, acting on other compounds
2007-08-09 Deleted SYNONYM racemase and epimerase activity, acting on other compounds
2005-08-10 Added SYNONYM racemase and epimerase activity, acting on other compounds
2005-05-19 Added DEFINITION Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016853 (isomerase activity)

Cross-references

Timestamp Action Category Detail
2006-02-09 Added XREF EC:5.1
2006-02-09 Deleted XREF EC:5.1.-.-
2001-03-30 Added XREF EC:5.1.-.-
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