spacer
spacer
Type a query for QuickGO...
You can reach the search box using alt+9 (Win/IE), alt+shift+9 (Win/Firefox) or ctrl+9 (Mac)
EBIDatabasesQuickGO

GO:0016836 hydro-lyase activity

Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.

Term Information

ID GO:0016836
Name hydro-lyase activity
Ontology Molecular Function
Definition Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
Comment
Secondary IDs

GONUTS Wiki Page

Cross-references associated with this term:

Database ID
EC 4.2.1
INTERPRO IPR015936
INTERPRO IPR012095
INTERPRO IPR004647
INTERPRO IPR010462
INTERPRO IPR006251
INTERPRO IPR010084
INTERPRO IPR008076
INTERPRO IPR007392
INTERPRO IPR003206
INTERPRO IPR009905
INTERPRO IPR010210
INTERPRO IPR010196

Web service: term information

Use this URI template to access this data as a service:

GTerm?id=termID&format=format

Full details can be found on the QuickGO Web Services page.

Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.

Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0016835 carbon-oxygen lyase activity
GO:0016836 hydro-lyase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0009978 allene oxide synthase activity
I GO:0017051 retinol dehydratase activity
I GO:0043956 3-hydroxypropionyl-CoA dehydratase activity
I GO:0043960 L-erythro-3-methylmalyl-CoA dehydratase activity
I GO:0047808 D(-)-tartrate dehydratase activity
I GO:0047818 D-fuconate dehydratase activity
I GO:0047820 D-glutamate cyclase activity
I GO:0047868 dimethylmaleate hydratase activity
I GO:0047508 (R)-2-methylmalate dehydratase activity
I GO:0047510 (S)-2-methylmalate dehydratase activity
I GO:0047547 2-methylcitrate dehydratase activity
I GO:0047558 3-cyanoalanine hydratase activity
I GO:0047584 4-oxalmesaconate hydratase activity
I GO:0047587 5-alpha-hydroxysteroid dehydratase activity
I GO:0003859 3-hydroxybutyryl-CoA dehydratase activity
I GO:0003861 3-isopropylmalate dehydratase activity
I GO:0003994 aconitate hydratase activity
I GO:0004089 carbonate dehydratase activity
I GO:0004122 cystathionine beta-synthase activity
I GO:0004160 dihydroxy-acid dehydratase activity
I GO:0030196 cyanide hydratase activity
I GO:0047929 gluconate dehydratase activity
I GO:0047987 hydroperoxide dehydratase activity
I GO:0050005 isohexenylglutaconyl-CoA hydratase activity
I GO:0050011 itaconyl-CoA hydratase activity
I GO:0050015 kievitone hydratase activity
I GO:0050020 L-arabinonate dehydratase activity
I GO:0050023 L-fuconate dehydratase activity
I GO:0050032 L-rhamnonate dehydratase activity
I GO:0050075 maleate hydratase activity
I GO:0050079 acetylenecarboxylate hydratase activity, producing 3-oxopropanoate
I GO:0050114 myo-inosose-2 dehydratase activity
I GO:0050151 oleate hydratase activity
I GO:0018807 6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity
I GO:0018808 trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity
I GO:0018809 E-phenylitaconyl-CoA hydratase activity
I GO:0018810 trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity
I GO:0018811 cyclohex-1-ene-1-carboxyl-CoA hydratase activity
I GO:0018812 3-hydroxyacyl-CoA dehydratase activity
I GO:0018813 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity
I GO:0018815 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity
I GO:0018816 2-hydroxyisobutyrate dehydratase activity
I GO:0018817 2-oxo-hept-3-ene-1,7-dioate hydratase activity
I GO:0018818 acetylene hydratase activity
I GO:0018819 lactoyl-CoA dehydratase activity
I GO:0018820 cyanamide hydratase activity
I GO:0018822 nitrile hydratase activity
I GO:0018823 cyclohexa-1,5-dienecarbonyl-CoA hydratase activity
I GO:0019171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
I GO:0003855 3-dehydroquinate dehydratase activity
I GO:0050202 octopamine dehydratase activity
I GO:0050215 propanediol dehydratase activity
I GO:0051909 acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate
I GO:0004300 enoyl-CoA hydratase activity
I GO:0004333 fumarate hydratase activity
I GO:0004409 homoaconitate hydratase activity
I GO:0004424 imidazoleglycerol-phosphate dehydratase activity
I GO:0004456 phosphogluconate dehydratase activity
I GO:0004490 methylglutaconyl-CoA hydratase activity
I GO:0043724 2-keto-3-deoxygalactonate aldolase activity
I GO:0043725 2-keto-3-deoxygluconate aldolase activity
I GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity
I GO:0050234 pyrazolylalanine synthase activity
I GO:0050315 synephrine dehydratase activity
I GO:0050346 trans-L-3-hydroxyproline dehydratase activity
I GO:0050377 UDP-glucose 4,6-dehydratase activity
I GO:0050401 xylonate dehydratase activity
I GO:0016508 long-chain-enoyl-CoA hydratase activity
I GO:0047448 5-dehydro-4-deoxyglucarate dehydratase activity
I GO:0047449 2-dehydro-3-deoxy-L-arabinonate dehydratase activity
I GO:0047450 crotonoyl-[acyl-carrier-protein] hydratase activity
I GO:0047452 protoaphin-aglucone dehydratase (cyclizing) activity
I GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity
I GO:0047454 phaseollidin hydratase activity
I GO:0047455 16-alpha-hydroxyprogesterone dehydratase activity
I GO:0047456 2-methylisocitrate dehydratase activity
I GO:0050474 (S)-norcoclaurine synthase activity
I GO:0050548 trans-feruloyl-CoA hydratase activity
I GO:0050549 cyclohexyl-isocyanide hydratase activity
I GO:0008684 2-oxopent-4-enoate hydratase activity
I GO:0008730 L(+)-tartrate dehydratase activity
I GO:0008735 carnitine dehydratase activity
I GO:0008789 altronate dehydratase activity
I GO:0008840 dihydrodipicolinate synthase activity
I GO:0008867 galactarate dehydratase activity
I GO:0008869 galactonate dehydratase activity
I GO:0008872 glucarate dehydratase activity
I GO:0008927 mannonate dehydratase activity
I GO:0018128 peptidyl-serine cyclase activity
I GO:0018135 peptidyl-cysteine cyclase activity
I GO:0047675 arabinonate dehydratase activity
I GO:0047733 CDP-glucose 4,6-dehydratase activity
I GO:0047769 arogenate dehydratase activity
I GO:0047780 citrate dehydratase activity
I GO:0004634 phosphopyruvate hydratase activity
I GO:0004655 porphobilinogen synthase activity
I GO:0004664 prephenate dehydratase activity
I GO:0004730 pseudouridylate synthase activity
I GO:0004834 tryptophan synthase activity
I GO:0004852 uroporphyrinogen-III synthase activity
I GO:0008446 GDP-mannose 4,6-dehydratase activity
I GO:0008460 dTDP-glucose 4,6-dehydratase activity
I GO:0008659 (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity
I GO:0016153 urocanate hydratase activity
I GO:0046405 glycerol dehydratase activity
I GO:0030411 scytalone dehydratase activity
I GO:0046565 3-dehydroshikimate dehydratase activity
I GO:0046570 5-methylthioribulose-1-phosphate 4-dehydratase activity
I GO:0043721 4-hydroxybutyryl-CoA dehydratase activity
I GO:0034917 2-methylhex-2-enoyl-CoA hydratase activity
I GO:0034953 perillyl-CoA hydratase activity
I GO:0043881 mesaconyl-CoA hydratase activity
I GO:0033987 2-hydroxyisoflavanone dehydratase activity
I GO:0033988 bile-acid 7alpha-dehydratase activity
I GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity
I GO:0033990 ectoine synthase activity
I GO:0033991 aldos-2-ulose dehydratase activity
I GO:0033992 1,5-anhydro-D-fructose dehydratase activity
I GO:0043748 O-succinylbenzoate synthase activity
I GO:0080023 3R-hydroxyacyl-CoA dehydratase activity
I GO:0034561 1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity
I GO:0034578 limonene 8-hydratase activity
I GO:0034581 4-methyloct-2-enoyl-CoA hydratase activity
I GO:0034829 2-hydroxydec-2,4-diene-1,10-dioate hydratase activity
I GO:0034839 menth-2-enone hydratase activity
I GO:0034846 naphthyl-2-methylene-succinyl-CoA lyase activity
I GO:0034856 2-hydroxyhexa-2,4-dienoate hydratase activity
I GO:0034867 2,4,4-trimethylpent-2-enoyl-CoA hydratase activity
I GO:0034890 endosulfan diol hydrolyase (cyclizing) activity
I GO:0034904 5-chloro-2-oxopent-4-enoate hydratase activity
I GO:0043809 methylthioribulose 1-phosphate dehydratase activity
I GO:0043717 2-hydroxyglutaryl-CoA dehydratase activity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

Help: filtering, analyzing and downloading annotation

Columns:
DB
ID
Alt
Symbol
Taxon
Qualifier
GO ID
GO Term name
Reference
Ev
With
A
Date
From
1 Filter:
Show:
Selected annotation
List proteins in selected annotation
All annotation to proteins in selected annotation
Columns shown:
DB
ID
splice
Symbol
Qualifier
GO ID
Reference
Evidence
With
Aspect
Name
Synonym
Type
Taxon
Taxon Name
Date
Source
GO Name
PubMed
RowID
Sequence
Choose the columns to be shown and click:
Choose protein identifier database
Use this filter to change between different sequence identifier types. QuickGO's default is to show annotations to UniProtKB (Swiss-Prot and TrEMBL) accession numbers.

UniProtKB - UniProtKB
UniProtKB/Swiss-Prot - UniProtKB/Swiss-Prot
UniProtKB/TrEMBL - UniProtKB/TrEMBL
IPI - IPI
dictyBase - dictyBase
EcoCyc - EcoCyc
EMBL - EMBL
ENSEMBL - ENSEMBL
FB - FB
GeneDB_Spombe - GeneDB_Spombe
GeneID - GeneID
GR - GR
TIGR_CMR - TIGR_CMR
MGI - MGI
RefSeq - RefSeq
TAIR - TAIR
UniGene - UniGene
WB - WB
ZFIN - ZFIN

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.
If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.
Filter annotations by protein IDs from any database:
QuickGO will map identifiers to UniProtKB accession numbers unless you have specified an alternative identifier type via the 'DB' filter box.
OR - select a list of proteins:
BHF-UCL BHF-UCL
KRUK KRUK
ReferenceGenome ReferenceGenome
Filter by taxonomy
To filter by species/taxonomic group, list taxon identifiers in the text box or select one of the pre-defined taxonomic groups below.
9606 Human
10090 Mouse
40674 Mammalia
3398 Magnoliophyta (flowering plants)
2759 Eukaryota
1117 Cyanobacteria
Visit NEWT to find identifiers for other taxonomic groups
Qualifier:
(none)
colocalizes_with colocalizes_with
contributes_to contributes_to
NOT NOT
NOT|colocalizes_with NOT|colocalizes_with
NOT|contributes_to NOT|contributes_to
GO Terms:
GO:0016836
Enter a list of GO identifiers (GO:nnnnnnn), separated by space, comma or newline characters

Use these terms as a GO slim
Select the set of relationships to be applied when slimming up annotations to the selected GO term set:
Default behaviour (is_a and part_of relationships only)
is_a only
is_a, part_of, regulates, positively_regulates and negatively_regulates
Use all relationships
Custom

Find annotations that directly associate the selected terms
Find annotations to descendants of these terms (annotations will display the original GO terms applied)
Annotated from any of these references:
GO_REF:* GO Reference
GO_REF:0000002 InterPro2GO
GO_REF:0000003 EC2GO
GO_REF:0000004 Swiss-Prot Keywords2GO
GO_REF:0000019 Compara
GO_REF:0000020 HAMAP2GO
GO_REF:0000023 Subcellular Location2GO
References (with or without database prefix):
With evidence:
IMP,IGI,IPI,IDA,IEP,EXP Manual Experimental
IMP,IGI,IPI,IDA,IEP,EXP,ISS,TAS,NAS,ND,IC,RCA Manual All
IMPinferred from mutant phenotype
IGIinferred from genetic interaction
IPIinferred from physical interaction
IGCInferred from Genomic Context
ISSinferred from sequence or structural similarity
IDAinferred from direct assay
IEPinferred from expression pattern
IEAinferred from electronic annotation
TAStraceable author statement
NASnon-traceable author statement
NDno data
ICinferred by curator
RCAreviewed computational annotation
ISAinferred from sequence alignment
EXPinferred from experiment
Annotated with reference:
EC:* Enzyme Code
HAMAP:* High-quality Automated and Manual Annotation of microbial Proteomes
InterPro:* InterPro
SP_KW:* UniProt Knowledgebase keywords
SP_SL:* UniProtKB Subcellular Location identifiers
UniProtKB:* UniProtKB
Annotated with (with or without database prefix):
Advanced search
View annotation:
Columns:
DB
ID
Alt
Symbol
Taxon
Qualifier
GO ID
GO Term name
Reference
Ev
With
A
Date
From
Sample size:
4 Download
Options: gzip: limit:
Format: . Current columns, Tab Separated Values: .

Web service: annotation

Use this URI template to access this data as a service:

GAnnotation?format=tsv&limit=max-number-of-rows{&gz}{&q=advanced query}{&field=value{,value}}

Full details can be found on the QuickGO Web Services page.

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
spacer
15ms
Hostnametomcat-7.ebi.ac.uk
Uptime11:21 5/2/2010
Data version2010-02-10-03-49-32
Terminal
spacer