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GO:0016836 hydro-lyase activity

Term Information

ID GO:0016836
Name hydro-lyase activity
Ontology Molecular Function
Definition Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
GONUTS GO:0016836 Wiki Page

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 4.2.1
InterPro IPR003206
InterPro IPR004647
InterPro IPR006251
InterPro IPR007392
InterPro IPR009905
InterPro IPR010084
InterPro IPR010196
InterPro IPR010210
InterPro IPR022852

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016836:
Relationship To GO:0016836 Child Term Child Term Name
Is a GO:0009978 allene oxide synthase activity
Is a GO:0017051 retinol dehydratase activity
Is a GO:0043956 3-hydroxypropionyl-CoA dehydratase activity
Is a GO:0043960 L-erythro-3-methylmalyl-CoA dehydratase activity
Is a GO:0047808 D(-)-tartrate dehydratase activity
Is a GO:0047818 D-fuconate dehydratase activity
Is a GO:0047820 D-glutamate cyclase activity
Is a GO:0047868 dimethylmaleate hydratase activity
Is a GO:0047508 (R)-2-methylmalate dehydratase activity
Is a GO:0047510 (S)-2-methylmalate dehydratase activity
Is a GO:0047547 2-methylcitrate dehydratase activity
Is a GO:0047558 3-cyanoalanine hydratase activity
Is a GO:0047584 4-oxalmesaconate hydratase activity
Is a GO:0047587 5-alpha-hydroxysteroid dehydratase activity
Is a GO:0003859 3-hydroxybutyryl-CoA dehydratase activity
Is a GO:0003861 3-isopropylmalate dehydratase activity
Is a GO:0003994 aconitate hydratase activity
Is a GO:0004089 carbonate dehydratase activity
Is a GO:0004122 cystathionine beta-synthase activity
Is a GO:0004160 dihydroxy-acid dehydratase activity
Is a GO:0030196 cyanide hydratase activity
Is a GO:0047929 gluconate dehydratase activity
Is a GO:0047987 hydroperoxide dehydratase activity
Is a GO:0050005 isohexenylglutaconyl-CoA hydratase activity
Is a GO:0050011 itaconyl-CoA hydratase activity
Is a GO:0050015 kievitone hydratase activity
Is a GO:0050020 L-arabinonate dehydratase activity
Is a GO:0050023 L-fuconate dehydratase activity
Is a GO:0050032 L-rhamnonate dehydratase activity
Is a GO:0050075 maleate hydratase activity
Is a GO:0050079 acetylenecarboxylate hydratase activity, producing 3-oxopropanoate
Is a GO:0050114 myo-inosose-2 dehydratase activity
Is a GO:0050151 oleate hydratase activity
Is a GO:0018807 6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity
Is a GO:0018808 trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity
Is a GO:0018809 E-phenylitaconyl-CoA hydratase activity
Is a GO:0018810 trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity
Is a GO:0018811 cyclohex-1-ene-1-carboxyl-CoA hydratase activity
Is a GO:0018812 3-hydroxyacyl-CoA dehydratase activity
Is a GO:0018813 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity
Is a GO:0018815 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity
Is a GO:0018816 2-hydroxyisobutyrate dehydratase activity
Is a GO:0018817 2-oxo-hept-3-ene-1,7-dioate hydratase activity
Is a GO:0018818 acetylene hydratase activity
Is a GO:0018819 lactoyl-CoA dehydratase activity
Is a GO:0018820 cyanamide hydratase activity
Is a GO:0018822 nitrile hydratase activity
Is a GO:0018823 cyclohexa-1,5-dienecarbonyl-CoA hydratase activity
Is a GO:0019171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
Is a GO:0003855 3-dehydroquinate dehydratase activity
Is a GO:0050202 octopamine dehydratase activity
Is a GO:0050215 propanediol dehydratase activity
Is a GO:0051909 acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate
Is a GO:0004300 enoyl-CoA hydratase activity
Is a GO:0004333 fumarate hydratase activity
Is a GO:0004409 homoaconitate hydratase activity
Is a GO:0004424 imidazoleglycerol-phosphate dehydratase activity
Is a GO:0004456 phosphogluconate dehydratase activity
Is a GO:0004490 methylglutaconyl-CoA hydratase activity
Is a GO:0043724 2-keto-3-deoxygalactonate aldolase activity
Is a GO:0043725 2-keto-3-deoxygluconate aldolase activity
Is a GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity
Is a GO:0050234 pyrazolylalanine synthase activity
Is a GO:0050315 synephrine dehydratase activity
Is a GO:0050346 trans-L-3-hydroxyproline dehydratase activity
Is a GO:0050377 UDP-glucose 4,6-dehydratase activity
Is a GO:0050401 xylonate dehydratase activity
Is a GO:0016508 long-chain-enoyl-CoA hydratase activity
Is a GO:0047448 5-dehydro-4-deoxyglucarate dehydratase activity
Is a GO:0047449 2-dehydro-3-deoxy-L-arabinonate dehydratase activity
Is a GO:0047452 protoaphin-aglucone dehydratase (cyclizing) activity
Is a GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity
Is a GO:0047454 phaseollidin hydratase activity
Is a GO:0047455 16-alpha-hydroxyprogesterone dehydratase activity
Is a GO:0047456 2-methylisocitrate dehydratase activity
Is a GO:0050474 (S)-norcoclaurine synthase activity
Is a GO:0050548 trans-feruloyl-CoA hydratase activity
Is a GO:0050549 cyclohexyl-isocyanide hydratase activity
Is a GO:0008684 2-oxopent-4-enoate hydratase activity
Is a GO:0008730 L(+)-tartrate dehydratase activity
Is a GO:0008735 carnitine dehydratase activity
Is a GO:0008789 altronate dehydratase activity
Is a GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase
Is a GO:0008867 galactarate dehydratase activity
Is a GO:0008869 galactonate dehydratase activity
Is a GO:0008872 glucarate dehydratase activity
Is a GO:0008927 mannonate dehydratase activity
Is a GO:0047675 arabinonate dehydratase activity
Is a GO:0047733 CDP-glucose 4,6-dehydratase activity
Is a GO:0047769 arogenate dehydratase activity
Is a GO:0047780 citrate dehydratase activity
Is a GO:0004634 phosphopyruvate hydratase activity
Is a GO:0004655 porphobilinogen synthase activity
Is a GO:0004664 prephenate dehydratase activity
Is a GO:0004730 pseudouridylate synthase activity
Is a GO:0004834 tryptophan synthase activity
Is a GO:0004852 uroporphyrinogen-III synthase activity
Is a GO:0008446 GDP-mannose 4,6-dehydratase activity
Is a GO:0008460 dTDP-glucose 4,6-dehydratase activity
Is a GO:0008659 (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity
Is a GO:0016153 urocanate hydratase activity
Is a GO:0046405 glycerol dehydratase activity
Is a GO:0030411 scytalone dehydratase activity
Is a GO:0046565 3-dehydroshikimate dehydratase activity
Is a GO:0046570 methylthioribulose 1-phosphate dehydratase activity
Is a GO:0043721 4-hydroxybutanoyl-CoA dehydratase activity
Is a GO:0034917 2-methylhex-2-enoyl-CoA hydratase activity
Is a GO:0034953 perillyl-CoA hydratase activity
Is a GO:0043881 mesaconyl-CoA hydratase activity
Is a GO:0033987 2-hydroxyisoflavanone dehydratase activity
Is a GO:0033988 bile-acid 7alpha-dehydratase activity
Is a GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity
Is a GO:0033990 ectoine synthase activity
Is a GO:0033991 aldos-2-ulose dehydratase activity
Is a GO:0033992 1,5-anhydro-D-fructose dehydratase activity
Is a GO:0043748 O-succinylbenzoate synthase activity
Is a GO:0080023 3R-hydroxyacyl-CoA dehydratase activity
Is a GO:0034561 1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity
Is a GO:0034578 limonene 8-hydratase activity
Is a GO:0034581 4-methyloct-2-enoyl-CoA hydratase activity
Is a GO:0034829 2-hydroxydec-2,4-diene-1,10-dioate hydratase activity
Is a GO:0034839 menth-2-enone hydratase activity
Is a GO:0034846 naphthyl-2-methylene-succinyl-CoA lyase activity
Is a GO:0034856 2-hydroxyhexa-2,4-dienoate hydratase activity
Is a GO:0034867 2,4,4-trimethylpent-2-enoyl-CoA hydratase activity
Is a GO:0034890 endosulfan diol hydrolyase (cyclizing) activity
Is a GO:0034904 5-chloro-2-oxopent-4-enoate hydratase activity
Is a GO:0043717 2-hydroxyglutaryl-CoA dehydratase activity
Is a GO:0019172 glyoxalase III activity
Is a GO:1990422 glyoxalase (glycolic acid-forming) activity
Is a GO:0052633 isocitrate hydro-lyase (cis-aconitate-forming) activity
Is a GO:0052855 ADP-dependent NAD(P)H-hydrate dehydratase activity
Is a GO:0098605 selenocystathionine beta-synthase activity
Is a GO:0052684 L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity
Is a GO:0061503 tRNA threonylcarbamoyladenosine dehydratase
Is a GO:0070497 6-carboxy-5,6,7,8-tetrahydropterin synthase activity

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016836. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016836 based on the entire annotation set Co-occurrence statistics for GO:0016836 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
2008-05-12 Deleted DEFINITION Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
2008-04-01 Updated RELATION is a GO:0016835 (carbon-oxygen lyase activity)
2006-02-09 Deleted XREF EC:4.2.1.-
2006-02-09 Added XREF EC:4.2.1
2003-08-06 Updated DEFINITION Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
2003-04-12 Updated DEFINITION The hydro-lyases (EC:4.2.1) are lyases that catalyze the breakage of a carbon-oxygen bond by elimination of water.
2003-03-26 Added DEFINITION The hydro-lyases (EC 4.2.1) are lyases that catalyze the breakage of a carbon-oxygen bond by elimination of water.
2003-03-19 Updated TERM hydro-lyase activity
2002-02-06 Updated TERM hydro-lyase
2001-04-03 Updated TERM hydro-lyase
2001-03-30 Added XREF EC:4.2.1.-
2001-03-30 Added TERM hydro-lyase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM hydro-lyase activity
2002-02-06 Updated TERM hydro-lyase
2001-04-03 Updated TERM hydro-lyase
2001-03-30 Added TERM hydro-lyase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
2008-05-12 Deleted DEFINITION Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
2003-08-06 Updated DEFINITION Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
2003-04-12 Updated DEFINITION The hydro-lyases (EC:4.2.1) are lyases that catalyze the breakage of a carbon-oxygen bond by elimination of water.
2003-03-26 Added DEFINITION The hydro-lyases (EC 4.2.1) are lyases that catalyze the breakage of a carbon-oxygen bond by elimination of water.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016835 (carbon-oxygen lyase activity)

Cross-references

Timestamp Action Category Detail
2006-02-09 Deleted XREF EC:4.2.1.-
2006-02-09 Added XREF EC:4.2.1
2001-03-30 Added XREF EC:4.2.1.-
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