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GO:0016832 aldehyde-lyase activity

Term Information

ID GO:0016832
Name aldehyde-lyase activity
Ontology Molecular Function
Definition Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.
Secondary IDs GO:0016228
GONUTS GO:0016832 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
broad aldolase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 4.1.2
InterPro IPR000771
InterPro IPR005593
InterPro IPR006268
InterPro IPR018969
InterPro IPR019789
InterPro IPR019790
InterPro IPR020868
InterPro IPR023001
InterPro IPR023593

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016832:
Relationship To GO:0016832 Child Term Child Term Name
Is a GO:0047864 dimethylaniline-N-oxide aldolase activity
Is a GO:0047905 fructose-6-phosphate phosphoketolase activity
Is a GO:0047906 fucosterol-epoxide lyase activity
Is a GO:0050013 2-dehydropantoate aldolase activity
Is a GO:0050014 ketotetrose-phosphate aldolase activity
Is a GO:0050041 lactate aldolase activity
Is a GO:0047606 hydroxynitrilase activity
Is a GO:0050179 phenylserine aldolase activity
Is a GO:0050193 phosphoketolase activity
Is a GO:0050217 propioin synthase activity
Is a GO:0043863 4-hydroxy-2-ketopimelate aldolase activity
Is a GO:0050352 trimethylamine-oxide aldolase activity
Is a GO:0047438 2-dehydro-3-deoxy-L-pentonate aldolase activity
Is a GO:0047439 3-deoxy-D-manno-octulosonate aldolase activity
Is a GO:0047440 2-dehydro-3-deoxy-D-pentonate aldolase activity
Is a GO:0047441 5-dehydro-2-deoxyphosphogluconate aldolase activity
Is a GO:0047442 17-alpha-hydroxyprogesterone aldolase activity
Is a GO:0050547 vanillin synthase activity
Is a GO:0004139 deoxyribose-phosphate aldolase activity
Is a GO:0004150 dihydroneopterin aldolase activity
Is a GO:0004332 fructose-bisphosphate aldolase activity
Is a GO:0004793 threonine aldolase activity
Is a GO:0008117 sphinganine-1-phosphate aldolase activity
Is a GO:0008672 2-dehydro-3-deoxyglucarate aldolase activity
Is a GO:0008674 2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity
Is a GO:0008675 2-dehydro-3-deoxy-phosphogluconate aldolase activity
Is a GO:0008700 4-hydroxy-2-oxoglutarate aldolase activity
Is a GO:0008738 L-fuculose-phosphate aldolase activity
Is a GO:0008994 rhamnulose-1-phosphate aldolase activity
Is a GO:0009025 tagatose-bisphosphate aldolase activity
Is a GO:0047695 benzoin aldolase activity
Is a GO:0046593 mandelonitrile lyase activity
Is a GO:0043876 D-threonine aldolase activity
Is a GO:0034529 2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity
Is a GO:0034531 2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity
Is a GO:0034537 2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity
Is a GO:0033984 indole-3-glycerol-phosphate lyase activity
Is a GO:0043801 hexulose-6-phosphate synthase activity
Is a GO:0103042 4-hydroxy-L-threonine aldolase activity
Is a GO:0061677 2-dehydro-3-deoxy-D-gluconate aldolase activity
Is a GO:0097023 fructose 6-phosphate aldolase activity
Is a GO:0061609 fructose-1-phosphate aldolase activity
Is a GO:0061595 6-deoxy-6-sulfofructose-1-phosphate aldolase activity
Is a GO:0052891 aliphatic (S)-hydroxynitrile lyase activity
Is a GO:0052892 aromatic (S)-hydroxynitrile lyase activity
Is a GO:0052919 aliphatic (R)-hydroxynitrile lyase activity

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016832. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016832 based on the entire annotation set Co-occurrence statistics for GO:0016832 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.
2008-05-12 Deleted DEFINITION Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.
2008-04-01 Updated RELATION is a GO:0016830 (carbon-carbon lyase activity)
2007-08-09 Added SYNONYM aldolase activity
2007-08-09 Deleted SYNONYM aldolase activity
2007-04-27 Updated DEFINITION Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.
2006-02-09 Deleted XREF EC:4.1.2.-
2006-02-09 Deleted XREF EC:4.1.-.-
2006-02-09 Added XREF EC:4.1.2
2004-08-22 Added XREF EC:4.1.-.-
2004-08-22 Added SECONDARY GO:0016228 (aldolase activity)
2004-08-22 Added SYNONYM aldolase activity
2004-08-21 Added DEFINITION Catalyzes the cleavage of a carbon-carbon bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.
2003-03-19 Updated TERM aldehyde-lyase activity
2002-02-06 Updated TERM aldehyde-lyase
2001-04-03 Updated TERM aldehyde-lyase
2001-03-30 Added XREF EC:4.1.2.-
2001-03-30 Added TERM aldehyde-lyase

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM aldehyde-lyase activity
2002-02-06 Updated TERM aldehyde-lyase
2001-04-03 Updated TERM aldehyde-lyase
2001-03-30 Added TERM aldehyde-lyase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.
2008-05-12 Deleted DEFINITION Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.
2007-08-09 Added SYNONYM aldolase activity
2007-08-09 Deleted SYNONYM aldolase activity
2007-04-27 Updated DEFINITION Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.
2004-08-22 Added SYNONYM aldolase activity
2004-08-21 Added DEFINITION Catalyzes the cleavage of a carbon-carbon bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016830 (carbon-carbon lyase activity)

Cross-references

Timestamp Action Category Detail
2006-02-09 Deleted XREF EC:4.1.2.-
2006-02-09 Deleted XREF EC:4.1.-.-
2006-02-09 Added XREF EC:4.1.2
2004-08-22 Added XREF EC:4.1.-.-
2001-03-30 Added XREF EC:4.1.2.-

Other

Timestamp Action Category Detail
2004-08-22 Added SECONDARY GO:0016228 (aldolase activity)
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