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GO:0016829 lyase activityCatalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
Term Information
GO SlimsThis term is present in the following GO Consortium-maintained GO slims:
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| Type | Synonym |
| narrow | other lyase activity |
| Database | ID |
| INTERPRO | IPR003159 |
| INTERPRO | IPR002220 |
| INTERPRO | IPR005661 |
| INTERPRO | IPR001906 |
| INTERPRO | IPR002915 |
| INTERPRO | IPR001597 |
| INTERPRO | IPR004646 |
| EC | 4 |
| INTERPRO | IPR004103 |
| INTERPRO | IPR018951 |
| INTERPRO | IPR002762 |
| INTERPRO | IPR005630 |
GO:0016850 other lyase activity |
(consider GO:0016829) |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | ||
![]() | GO:0003824 catalytic activity | |
![]() | ![]() | GO:0016829 lyase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| I | GO:0009985 dihydroflavonol(thiole) lyase activity |
| I | GO:0004325 ferrochelatase activity |
| I | GO:0016852 sirohydrochlorin cobaltochelatase activity |
| I | GO:0018835 carbon phosphorus lyase activity |
| I | GO:0018836 alkylmercury lyase activity |
| I | GO:0047720 indoleacetaldoxime dehydratase activity |
| I | GO:0016830 carbon-carbon lyase activity |
| I | GO:0016835 carbon-oxygen lyase activity |
| I | GO:0016840 carbon-nitrogen lyase activity |
| I | GO:0016846 carbon-sulfur lyase activity |
| I | GO:0016848 carbon-halide lyase activity |
| I | GO:0016849 phosphorus-oxygen lyase activity |
| I | GO:0043729 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity |
| I | GO:0043779 cobalt-precorrin-5A acetaldehyde-lyase activity |
| I | GO:0046567 aphidicolan-16 beta-ol synthase activity |
| Code | Relationship |
| P | part of |
| I | is a |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-21-04-03-45 |