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GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

Term Information

ID GO:0016709
Name oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
Ontology Molecular Function
Definition Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
GONUTS GO:0016709 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.14.13
InterPro IPR010971
InterPro IPR011772
InterPro IPR012078
InterPro IPR018168

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016709:
Relationship To GO:0016709 Child Term Child Term Name
Is a GO:0004506 squalene monooxygenase activity
Is a GO:0008398 sterol 14-demethylase activity
Is a GO:0051777 ent-kaurenoate oxidase activity
Is a GO:0051778 ent-7-alpha-hydroxykaurenoate oxidase activity
Is a GO:0051779 gibberellin 12-aldehyde oxidase activity
Is a GO:0047799 cyclopentanone monooxygenase activity
Is a GO:0018489 vanillate monooxygenase activity
Is a GO:0018630 3,5-xylenol methylhydroxylase activity
Is a GO:0018631 phenylacetate hydroxylase activity
Is a GO:0018632 4-nitrophenol 4-monooxygenase activity
Is a GO:0018633 dimethyl sulfide monooxygenase activity
Is a GO:0018634 alpha-pinene monooxygenase [NADH] activity
Is a GO:0018636 phenanthrene 9,10-monooxygenase activity
Is a GO:0018637 1-hydroxy-2-naphthoate hydroxylase activity
Is a GO:0018638 toluene 4-monooxygenase activity
Is a GO:0018639 xylene monooxygenase activity
Is a GO:0018640 dibenzothiophene monooxygenase activity
Is a GO:0018641 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity
Is a GO:0018642 chlorophenol 4-monooxygenase activity
Is a GO:0018643 carbon disulfide oxygenase activity
Is a GO:0018644 toluene 2-monooxygenase activity
Is a GO:0018645 alkene monooxygenase activity
Is a GO:0018646 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity
Is a GO:0018647 phenanthrene 1,2-monooxygenase activity
Is a GO:0018648 methanesulfonate monooxygenase activity
Is a GO:0018649 tetrahydrofuran hydroxylase activity
Is a GO:0018650 styrene monooxygenase activity
Is a GO:0018651 toluene-4-sulfonate monooxygenase activity
Is a GO:0018652 toluene-sulfonate methyl-monooxygenase activity
Is a GO:0018653 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity
Is a GO:0018654 2-hydroxy-phenylacetate hydroxylase activity
Is a GO:0018655 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity
Is a GO:0018656 phenanthrene 3,4-monooxygenase activity
Is a GO:0018657 toluene 3-monooxygenase activity
Is a GO:0018658 salicylate 1-monooxygenase activity
Is a GO:0018659 4-hydroxybenzoate 3-monooxygenase activity
Is a GO:0018660 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity
Is a GO:0018661 orcinol 2-monooxygenase activity
Is a GO:0018662 phenol 2-monooxygenase activity
Is a GO:0018663 2,6-dihydroxypyridine 3-monooxygenase activity
Is a GO:0018664 benzoate 4-monooxygenase activity
Is a GO:0018665 4-hydroxyphenylacetate 1-monooxygenase activity
Is a GO:0018666 2,4-dichlorophenol 6-monooxygenase activity
Is a GO:0018667 cyclohexanone monooxygenase activity
Is a GO:0018668 3-hydroxybenzoate 4-monooxygenase activity
Is a GO:0018669 3-hydroxybenzoate 6-monooxygenase activity
Is a GO:0018670 4-aminobenzoate 1-monooxygenase activity
Is a GO:0018671 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity
Is a GO:0018672 anthranilate 3-monooxygenase (deaminating) activity
Is a GO:0018673 anthraniloyl-CoA monooxygenase activity
Is a GO:0047505 (-)-menthol monooxygenase activity
Is a GO:0047544 2-hydroxybiphenyl 3-monooxygenase activity
Is a GO:0047549 2-nitrophenol 2-monooxygenase activity
Is a GO:0015049 methane monooxygenase activity
Is a GO:0047957 4'-methoxyisoflavone 2'-hydroxylase activity
Is a GO:0048000 isoflavone 3'-hydroxylase activity
Is a GO:0050051 leukotriene-B4 20-monooxygenase activity
Is a GO:0050052 leukotriene-E4 20-monooxygenase activity
Is a GO:0050091 melilotate 3-monooxygenase activity
Is a GO:0047597 6-oxocineole dehydrogenase activity
Is a GO:0048529 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity
Is a GO:0018677 pentachlorophenol monooxygenase activity
Is a GO:0018678 4-hydroxybenzoate 1-hydroxylase activity
Is a GO:0050183 phosphatidylcholine 12-monooxygenase activity
Is a GO:0004498 calcidiol 1-monooxygenase activity
Is a GO:0004499 N,N-dimethylaniline monooxygenase activity
Is a GO:0004502 kynurenine 3-monooxygenase activity
Is a GO:0004517 nitric-oxide synthase activity
Is a GO:0008123 cholesterol 7-alpha-monooxygenase activity
Is a GO:0047082 3,9-dihydroxypterocarpan 6a-monooxygenase activity
Is a GO:0047083 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity
Is a GO:0047084 methyltetrahydroprotoberberine 14-monooxygenase activity
Is a GO:0047085 hydroxyphenylacetonitrile 2-monooxygenase activity
Is a GO:0047086 ketosteroid monooxygenase activity
Is a GO:0047087 protopine 6-monooxygenase activity
Is a GO:0047088 dihydrosanguinarine 10-monooxygenase activity
Is a GO:0047089 dihydrochelirubine 12-monooxygenase activity
Is a GO:0047090 benzoyl-CoA 3-monooxygenase activity
Is a GO:0047091 L-lysine 6-monooxygenase (NADPH) activity
Is a GO:0047092 27-hydroxycholesterol 7-alpha-monooxygenase activity
Is a GO:0047093 4-hydroxyquinoline 3-monooxygenase activity
Is a GO:0047094 3-hydroxyphenylacetate 6-hydroxylase activity
Is a GO:0047095 2-hydroxycyclohexanone 2-monooxygenase activity
Is a GO:0050246 questin monooxygenase activity
Is a GO:0050326 taxifolin 8-monooxygenase activity
Is a GO:0050344 trans-cinnamate 2-monooxygenase activity
Is a GO:0050370 tyrosine N-monooxygenase activity
Is a GO:0009540 zeaxanthin epoxidase [overall] activity
Is a GO:0019113 limonene monooxygenase activity
Is a GO:0047638 albendazole monooxygenase activity
Is a GO:0050591 quinine 3-monooxygenase activity
Is a GO:0050592 4-hydroxyphenylacetaldehyde oxime monooxygenase activity
Is a GO:0050593 N-methylcoclaurine 3'-monooxygenase activity
Is a GO:0050594 tabersonine 16-hydroxylase activity
Is a GO:0050595 7-deoxyloganin 7-hydroxylase activity
Is a GO:0050596 vinorine hydroxylase activity
Is a GO:0050597 taxane 10-beta-hydroxylase activity
Is a GO:0050598 taxane 13-alpha-hydroxylase activity
Is a GO:0008688 3-(3-hydroxyphenyl)propionate hydroxylase activity
Is a GO:0047670 anhydrotetracycline monooxygenase activity
Is a GO:0047749 cholestanetriol 26-monooxygenase activity
Is a GO:0047717 imidazoleacetate 4-monooxygenase activity
Is a GO:0018601 4-nitrophenol 2-monooxygenase activity
Is a GO:0000254 C-4 methylsterol oxidase activity
Is a GO:0018471 4-chlorobenzaldehyde oxidase activity
Is a GO:0016710 trans-cinnamate 4-monooxygenase activity
Is a GO:0016711 flavonoid 3'-monooxygenase activity
Is a GO:0043719 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity
Is a GO:0052582 (+)-menthofuran synthase activity
Is a GO:0052615 ent-kaurene oxidase activity
Is a GO:0052616 ent-kaur-16-en-19-ol oxidase activity
Is a GO:0052617 ent-kaur-16-en-19-al oxidase activity
Is a GO:0043818 precorrin-3B synthase activity
Is a GO:0052662 zeaxanthin epoxidase activity
Is a GO:0052663 antheraxanthin epoxidase activity
Is a GO:0010295 (+)-abscisic acid 8'-hydroxylase activity
Is a GO:0034526 2-methylnaphthalene hydroxylase activity
Is a GO:0034534 1-methylnaphthalene hydroxylase activity
Is a GO:0034560 bisphenol A hydroxylase A activity
Is a GO:0034785 salicylate 5-hydroxylase activity
Is a GO:0034791 isobutylamine N-hydroxylase activity
Is a GO:0034802 branched-chain dodecylbenzene sulfonate monooxygenase activity
Is a GO:0034819 3-HSA hydroxylase activity
Is a GO:0034894 4-hydroxypyridine-3-hydroxylase activity
Is a GO:0034899 trimethylamine monooxygenase activity
Is a GO:0033766 2-hydroxyquinoline 8-monooxygenase activity
Is a GO:0033767 4-hydroxyacetophenone monooxygenase activity
Is a GO:0033769 glyceollin synthase activity
Is a GO:0033770 2-hydroxyisoflavanone synthase activity
Is a GO:0033771 licodione synthase activity
Is a GO:0033772 flavonoid 3',5'-hydroxylase activity
Is a GO:0033773 isoflavone 2'-hydroxylase activity
Is a GO:0033775 deoxysarpagine hydroxylase activity
Is a GO:0033776 phenylacetone monooxygenase activity
Is a GO:0033777 lithocholate 6beta-hydroxylase activity
Is a GO:0033778 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity
Is a GO:0033779 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity
Is a GO:0033780 taurochenodeoxycholate 6alpha-hydroxylase activity
Is a GO:0033781 cholesterol 24-hydroxylase activity
Is a GO:0033782 24-hydroxycholesterol 7alpha-hydroxylase activity
Is a GO:0033783 25-hydroxycholesterol 7alpha-hydroxylase activity
Is a GO:0033784 senecionine N-oxygenase activity
Is a GO:0043731 6-hydroxynicotinate 3-monooxygenase activity
Is a GO:0036199 cholest-4-en-3-one 26-monooxygenase activity
Is a GO:0036200 3-ketosteroid 9-alpha-monooxygenase activity
Is a GO:0036201 ent-isokaurene C2-hydroxylase activity
Is a GO:0036202 ent-cassa-12,15-diene 11-hydroxylase activity
Is a GO:0036203 taxoid 14-beta-hydroxylase activity
Is a GO:0097266 phenylacetyl-CoA 1,2-epoxidase activity
Is a GO:0090489 L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)
Is a GO:0090490 L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)
Is a GO:0090491 N-hydroxy-L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)
Is a GO:0036204 abieta-7,13-dien-18-ol hydroxylase activity
Is a GO:0072533 tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity
Is a GO:0072532 tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity
Is a GO:0036189 abieta-7,13-diene hydroxylase activity
Is a GO:0036190 indole-2-monooxygenase activity
Is a GO:0036191 indolin-2-one monooxygenase activity
Is a GO:0036192 3-hydroxyindolin-2-one monooxygenase activity
Is a GO:0036193 2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity
Is a GO:0036209 9beta-pimara-7,15-diene oxidase activity
Is a GO:0097007 4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity
Is a GO:0097008 (3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity
Is a GO:0036239 taxoid 7beta-hydroxylase activity
Is a GO:0052870 tocopherol omega-hydroxylase activity
Is a GO:0052872 tocotrienol omega-hydroxylase activity

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016709. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016709 based on the entire annotation set Co-occurrence statistics for GO:0016709 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-01-13 Updated TERM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
2013-01-13 Added SYNONYM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
2008-05-13 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
2008-05-12 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
2008-04-01 Updated RELATION is a GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)
2008-04-01 Updated RELATION is a GO:0004497 (monooxygenase activity)
2006-11-28 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
2006-11-25 Updated TERM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
2006-02-09 Added XREF EC:1.14.13
2006-02-09 Deleted XREF EC:1.14.13.-
2003-03-25 Updated TERM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of one atom of oxygen
2003-03-19 Updated TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of one atom of oxygen activity
2002-02-06 Updated TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of one atom of oxygen
2001-04-03 Updated TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of one atom of oxygen
2001-03-30 Added XREF EC:1.14.13.-
2001-03-30 Added TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of one atom of oxygen

Term

Timestamp Action Category Detail
2013-01-13 Updated TERM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
2006-11-25 Updated TERM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
2003-03-25 Updated TERM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of one atom of oxygen
2003-03-19 Updated TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of one atom of oxygen activity
2002-02-06 Updated TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of one atom of oxygen
2001-04-03 Updated TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of one atom of oxygen
2001-03-30 Added TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of one atom of oxygen

Definition/synonyms

Timestamp Action Category Detail
2013-01-13 Added SYNONYM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
2008-05-13 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
2008-05-12 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
2006-11-28 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)
2008-04-01 Updated RELATION is a GO:0004497 (monooxygenase activity)

Cross-references

Timestamp Action Category Detail
2006-02-09 Added XREF EC:1.14.13
2006-02-09 Deleted XREF EC:1.14.13.-
2001-03-30 Added XREF EC:1.14.13.-
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