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GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

Term Information

ID	GO:0016709
Name	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
Ontology	Molecular Function
Definition	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
Comment

Cross-references associated with this term:

Database	ID
INTERPRO	IPR010971
INTERPRO	IPR011772
INTERPRO	IPR012078
EC	1.14.13

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GTerm?id=termID&format=format

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Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0003674 molecular_function

GO:0003824 catalytic activity

GO:0016491 oxidoreductase activity

GO:0004497 monooxygenase activity

GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen

Relationship key

Code	Relationship
	part of
	is a
	regulates
	+ve regulates
	-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:

I	GO:0008398 sterol 14-demethylase activity
I	GO:0051777 ent-kaurenoate oxidase activity
I	GO:0051778 ent-7-alpha-hydroxykaurenoate oxidase activity
I	GO:0051779 gibberellin 12-aldehyde oxidase activity
I	GO:0047799 cyclopentanone monooxygenase activity
I	GO:0018489 vanillate monooxygenase activity
I	GO:0018630 3,5-xylenol methylhydroxylase activity
I	GO:0018631 phenylacetate hydroxylase activity
I	GO:0018632 4-nitrophenol 4-monooxygenase activity
I	GO:0018633 dimethyl sulfide monooxygenase activity
I	GO:0018634 alpha-pinene monooxygenase [NADH] activity
I	GO:0018636 phenanthrene 9,10-monooxygenase activity
I	GO:0018637 1-hydroxy-2-naphthoate hydroxylase activity
I	GO:0018638 toluene 4-monooxygenase activity
I	GO:0018639 xylene monooxygenase activity
I	GO:0018640 dibenzothiophene monooxygenase activity
I	GO:0018641 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity
I	GO:0018642 chlorophenol 4-monooxygenase activity
I	GO:0018643 carbon disulfide oxygenase activity
I	GO:0018644 toluene 2-monooxygenase activity
I	GO:0018645 alkene monooxygenase activity
I	GO:0018646 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity
I	GO:0018647 phenanthrene 1,2-monooxygenase activity
I	GO:0018648 methanesulfonate monooxygenase activity
I	GO:0018649 tetrahydrofuran hydroxylase activity
I	GO:0018650 styrene monooxygenase activity
I	GO:0018651 toluene-4-sulfonate monooxygenase activity
I	GO:0018652 toluene-sulfonate methyl-monooxygenase activity
I	GO:0018653 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity
I	GO:0018654 2-hydroxy-phenylacetate hydroxylase activity
I	GO:0018655 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity
I	GO:0018656 phenanthrene 3,4-monooxygenase activity
I	GO:0018657 toluene 3-monooxygenase activity
I	GO:0018658 salicylate 1-monooxygenase activity
I	GO:0018659 4-hydroxybenzoate 3-monooxygenase activity
I	GO:0018660 4-hydroxyphenylacetate 3-monooxygenase activity
I	GO:0018661 orcinol 2-monooxygenase activity
I	GO:0018662 phenol 2-monooxygenase activity
I	GO:0018663 2,6-dihydroxypyridine 3-monooxygenase activity
I	GO:0018664 benzoate 4-monooxygenase activity
I	GO:0018665 4-hydroxyphenylacetate 1-monooxygenase activity
I	GO:0018666 2,4-dichlorophenol 6-monooxygenase activity
I	GO:0018667 cyclohexanone monooxygenase activity
I	GO:0018668 3-hydroxybenzoate 4-monooxygenase activity
I	GO:0018669 3-hydroxybenzoate 6-monooxygenase activity
I	GO:0018670 4-aminobenzoate 1-monooxygenase activity
I	GO:0018671 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity
I	GO:0018672 anthranilate 3-monooxygenase (deaminating) activity
I	GO:0018673 anthraniloyl-CoA monooxygenase activity
I	GO:0047505 (-)-menthol monooxygenase activity
I	GO:0047544 2-hydroxybiphenyl 3-monooxygenase activity
I	GO:0047549 2-nitrophenol 2-monooxygenase activity
I	GO:0015049 methane monooxygenase activity
I	GO:0047957 4'-methoxyisoflavone 2'-hydroxylase activity
I	GO:0048000 isoflavone 3'-hydroxylase activity
I	GO:0050051 leukotriene-B4 20-monooxygenase activity
I	GO:0050052 leukotriene-E4 20-monooxygenase activity
I	GO:0050091 melilotate 3-monooxygenase activity
I	GO:0047597 6-oxocineole dehydrogenase activity
I	GO:0048529 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity
I	GO:0018677 pentachlorophenol monooxygenase activity
I	GO:0018678 4-hydroxybenzoate 1-hydroxylase activity
I	GO:0050183 phosphatidylcholine 12-monooxygenase activity
I	GO:0004498 calcidiol 1-monooxygenase activity
I	GO:0004499 flavin-containing monooxygenase activity
I	GO:0004502 kynurenine 3-monooxygenase activity
I	GO:0004517 nitric-oxide synthase activity
I	GO:0008123 cholesterol 7-alpha-monooxygenase activity
I	GO:0047082 3,9-dihydroxypterocarpan 6a-monooxygenase activity
I	GO:0047083 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity
I	GO:0047084 methyltetrahydroprotoberberine 14-monooxygenase activity
I	GO:0047085 hydroxyphenylacetonitrile 2-monooxygenase activity
I	GO:0047086 ketosteroid monooxygenase activity
I	GO:0047087 protopine 6-monooxygenase activity
I	GO:0047088 dihydrosanguinarine 10-monooxygenase activity
I	GO:0047089 dihydrochelirubine 12-monooxygenase activity
I	GO:0047090 benzoyl-CoA 3-monooxygenase activity
I	GO:0047091 L-lysine 6-monooxygenase (NADPH) activity
I	GO:0047092 27-hydroxycholesterol 7-alpha-monooxygenase activity
I	GO:0047093 4-hydroxyquinoline 3-monooxygenase activity
I	GO:0047094 3-hydroxyphenylacetate 6-hydroxylase activity
I	GO:0047095 2-hydroxycyclohexanone 2-monooxygenase activity
I	GO:0050246 questin monooxygenase activity
I	GO:0050326 taxifolin 8-monooxygenase activity
I	GO:0050344 trans-cinnamate 2-monooxygenase activity
I	GO:0050370 tyrosine N-monooxygenase activity
I	GO:0009540 zeaxanthin epoxidase activity
I	GO:0019113 limonene monooxygenase activity
I	GO:0047638 albendazole monooxygenase activity
I	GO:0050591 quinine 3-monooxygenase activity
I	GO:0050592 4-hydroxyphenylacetaldehyde oxime monooxygenase activity
I	GO:0050593 N-methylcoclaurine 3'-monooxygenase activity
I	GO:0050594 tabersonine 16-hydroxylase activity
I	GO:0050595 7-deoxyloganin 7-hydroxylase activity
I	GO:0050596 vinorine hydroxylase activity
I	GO:0050597 taxane 10-beta-hydroxylase activity
I	GO:0050598 taxane 13-alpha-hydroxylase activity
I	GO:0008688 3-(3-hydroxy-phenyl)propionate hydroxylase activity
I	GO:0047670 anhydrotetracycline monooxygenase activity
I	GO:0047749 cholestanetriol 26-monooxygenase activity
I	GO:0047717 imidazoleacetate 4-monooxygenase activity
I	GO:0010241 ent-kaurene oxidase activity
I	GO:0018601 4-nitrophenol 2-monooxygenase activity
I	GO:0000254 C-4 methylsterol oxidase activity
I	GO:0018471 4-chlorobenzaldehyde oxidase activity
I	GO:0016710 trans-cinnamate 4-monooxygenase activity
I	GO:0016711 flavonoid 3'-monooxygenase activity
I	GO:0043719 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity
I	GO:0043818 precorrin-3B synthase activity
I	GO:0010295 (+)-abscisic acid 8'-hydroxylase activity
I	GO:0034526 2-methylnaphthalene hydroxylase activity
I	GO:0034534 1-methylnaphthalene hydroxylase activity
I	GO:0034560 bisphenol A hydroxylase A activity
I	GO:0034785 salicylate 5-hydroxylase activity
I	GO:0034791 isobutylamine N-hydroxylase activity
I	GO:0034802 branched-chain dodecylbenzene sulfonate monooxygenase activity
I	GO:0034819 3-HSA hydroxylase activity
I	GO:0034894 4-hydroxypyridine-3-hydroxylase activity
I	GO:0034899 trimethylamine monooxygenase activity
I	GO:0033766 2-hydroxyquinoline 8-monooxygenase activity
I	GO:0033767 4-hydroxyacetophenone monooxygenase activity
I	GO:0033769 glyceollin synthase activity
I	GO:0033770 2-hydroxyisoflavanone synthase activity
I	GO:0033771 licodione synthase activity
I	GO:0033772 flavonoid 3',5'-hydroxylase activity
I	GO:0033773 isoflavone 2'-hydroxylase activity
I	GO:0033775 deoxysarpagine hydroxylase activity
I	GO:0033776 phenylacetone monooxygenase activity
I	GO:0033777 lithocholate 6beta-hydroxylase activity
I	GO:0033778 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity
I	GO:0033779 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity
I	GO:0033780 taurochenodeoxycholate 6alpha-hydroxylase activity
I	GO:0033781 cholesterol 24-hydroxylase activity
I	GO:0033782 24-hydroxycholesterol 7alpha-hydroxylase activity
I	GO:0033783 25-hydroxycholesterol 7alpha-hydroxylase activity
I	GO:0033784 senecionine N-oxygenase activity
I	GO:0043731 6-hydroxynicotinate 3-monooxygenase activity

Relationship key

Code	Relationship
P	part of
I	is a

Protein Annotation

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GAnnotation?format=tsv&limit=max-number-of-rows{&gz}{&q=advanced query}{&field=value{,value}}

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Co-occurring Terms

Co-occurrence statistics

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Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.

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