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GO:0016708 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor

Term Information

ID GO:0016708
Name oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
Ontology Molecular Function
Definition Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor.
GONUTS GO:0016708 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.14.12
InterPro IPR015879
InterPro IPR017641

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016708:
Relationship To GO:0016708 Child Term Child Term Name
Is a GO:0018603 nitrobenzene 1,2-dioxygenase activity
Is a GO:0018604 4-aminobenzoate 3,4-dioxygenase (deaminating) activity
Is a GO:0018606 benzenesulfonate dioxygenase activity
Is a GO:0018607 1-indanone monooxygenase activity
Is a GO:0018608 1-indanone dioxygenase activity
Is a GO:0018609 chlorobenzene dioxygenase activity
Is a GO:0018610 dibenzofuran 4,4a-dioxygenase activity
Is a GO:0018611 toluate dioxygenase activity
Is a GO:0018612 dibenzothiophene dioxygenase activity
Is a GO:0018613 9-fluorenone dioxygenase activity
Is a GO:0018614 ethylbenzene dioxygenase activity
Is a GO:0018615 2-indanone monooxygenase activity
Is a GO:0018616 trihydroxytoluene dioxygenase activity
Is a GO:0018617 4-aminobenzenesulfonate 3,4-dioxygenase (deaminating) activity
Is a GO:0018618 anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity
Is a GO:0018619 benzene 1,2-dioxygenase activity
Is a GO:0018620 phthalate 4,5-dioxygenase activity
Is a GO:0018621 4-sulfobenzoate 3,4-dioxygenase activity
Is a GO:0018622 4-chlorophenylacetate 3,4-dioxygenase activity
Is a GO:0018623 benzoate 1,2-dioxygenase activity
Is a GO:0018624 toluene dioxygenase activity
Is a GO:0018625 naphthalene 1,2-dioxygenase activity
Is a GO:0018626 2-chlorobenzoate 1,2-dioxygenase activity
Is a GO:0018627 2-aminobenzenesulfonate 2,3-dioxygenase activity
Is a GO:0018628 terephthalate 1,2-dioxygenase activity
Is a GO:0018629 2-hydroxyquinoline 5,6-dioxygenase activity
Is a GO:0047592 5-pyridoxate dioxygenase activity
Is a GO:0018687 biphenyl 2,3-dioxygenase activity
Is a GO:0008695 3-phenylpropionate dioxygenase activity
Is a GO:0047081 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity
Is a GO:0008941 nitric oxide dioxygenase activity
Is a GO:0034906 N-isopropylaniline 1,2-dixoxygenase activity
Is a GO:0034907 acetanilide 1,2-dioxygenase activity
Is a GO:0034908 2-chloro-N-isopropylacetanilide 1,2-dioxygenase activity
Is a GO:0034911 phthalate 3,4-dioxygenase activity
Is a GO:0034954 diphenyl ether 2,3-dioxygenase activity
Is a GO:0034521 1-naphthoic acid dioxygenase activity
Is a GO:0034825 tetralin ring-hydroxylating dioxygenase activity

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016708. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016708 based on the entire annotation set Co-occurrence statistics for GO:0016708 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-01-13 Added SYNONYM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor
2013-01-13 Updated TERM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
2011-11-18 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen is incorporated into one donor.
2011-11-18 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor.
2008-05-13 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen is incorporated into one donor.
2008-05-12 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen is incorporated into one donor.
2008-04-01 Updated RELATION is a GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)
2008-04-01 Updated RELATION is a GO:0051213 (dioxygenase activity)
2006-11-28 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen is incorporated into one donor.
2006-11-25 Updated TERM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor
2006-02-09 Added XREF EC:1.14.12
2006-02-09 Deleted XREF EC:1.14.12.-
2003-03-25 Updated TERM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of two atoms of oxygen into one donor
2003-03-19 Updated TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of two atoms of oxygen into one donor activity
2002-02-06 Updated TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of two atoms of oxygen into one donor
2001-04-03 Updated TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of two atoms of oxygen into one donor
2001-03-30 Added XREF EC:1.14.12.-
2001-03-30 Added TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of two atoms of oxygen into one donor

Term

Timestamp Action Category Detail
2013-01-13 Updated TERM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor
2006-11-25 Updated TERM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor
2003-03-25 Updated TERM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of two atoms of oxygen into one donor
2003-03-19 Updated TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of two atoms of oxygen into one donor activity
2002-02-06 Updated TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of two atoms of oxygen into one donor
2001-04-03 Updated TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of two atoms of oxygen into one donor
2001-03-30 Added TERM oxidoreductase, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD or NADH as one donor, and incorporation of two atoms of oxygen into one donor

Definition/synonyms

Timestamp Action Category Detail
2013-01-13 Added SYNONYM oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor
2011-11-18 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen is incorporated into one donor.
2011-11-18 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor.
2008-05-13 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen is incorporated into one donor.
2008-05-12 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen is incorporated into one donor.
2006-11-28 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen is incorporated into one donor.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)
2008-04-01 Updated RELATION is a GO:0051213 (dioxygenase activity)

Cross-references

Timestamp Action Category Detail
2006-02-09 Added XREF EC:1.14.12
2006-02-09 Deleted XREF EC:1.14.12.-
2001-03-30 Added XREF EC:1.14.12.-
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