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GO:0016651 oxidoreductase activity, acting on NAD(P)H

Term Information

ID GO:0016651
Name oxidoreductase activity, acting on NAD(P)H
Ontology Molecular Function
Definition Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
Comment Note that enzymes of class EC:1.6.99.- should also be annotated to this term.
GONUTS GO:0016651 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related oxidoreductase activity, acting on NADH or NADPH
narrow oxidoreductase activity, acting on NADH or NADPH, other acceptor
narrow NAD(P)H dehydrogenase

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 1.6
InterPro IPR001133
InterPro IPR001135
InterPro IPR006806
InterPro IPR006885
InterPro IPR010185
InterPro IPR010218
InterPro IPR010226
InterPro IPR010228
InterPro IPR011537
InterPro IPR011982
InterPro IPR012081
InterPro IPR014029
InterPro IPR014406
InterPro IPR015405
InterPro IPR020396
InterPro IPR022885
InterPro IPR023043

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0008751 NAD(P)H dehydrogenase CONSIDER GO:0016651
GO:0016659 oxidoreductase activity, acting on NADH or NADPH, other acceptor CONSIDER GO:0016651

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016651:
Relationship To GO:0016651 Child Term Child Term Name
Is a GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
Is a GO:0018538 epoxide carboxylase activity
Is a GO:0003954 NADH dehydrogenase activity
Is a GO:0003959 NADPH dehydrogenase activity
Is a GO:0046424 ferulate 5-hydroxylase activity
Is a GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
Is a GO:0016652 oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor
Is a GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
Is a GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
Is a GO:0016657 oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor
Is a GO:0098623 selenite reductase activity
Is a GO:0098624 3'-Phosphoadenylylselenate reductase activity
Is a GO:0098625 methylselenol reductase activity
Is a GO:0098626 methylseleninic acid reductase activity
Is a GO:0052808 reduced coenzyme F420:NADP+ oxidoreductase activity

Protein Annotation

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GO Identifier
GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016651. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016651 based on the entire annotation set Co-occurrence statistics for GO:0016651 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-01-13 Updated TERM oxidoreductase activity, acting on NAD(P)H
2013-01-13 Added SYNONYM oxidoreductase activity, acting on NADH or NADPH
2008-05-13 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
2008-05-12 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
2008-04-01 Updated RELATION is a GO:0016491 (oxidoreductase activity)
2007-08-09 Added SYNONYM NAD(P)H dehydrogenase
2007-08-09 Added SYNONYM oxidoreductase activity, acting on NADH or NADPH, other acceptor
2007-08-09 Deleted SYNONYM NAD(P)H dehydrogenase
2007-08-09 Deleted SYNONYM oxidoreductase activity, acting on NADH or NADPH, other acceptor
2006-02-09 Added XREF EC:1.6
2006-02-09 Deleted XREF EC:1.6.-.-
2005-08-10 Added SYNONYM NAD(P)H dehydrogenase
2005-08-10 Added SYNONYM oxidoreductase activity, acting on NADH or NADPH, other acceptor
2003-09-25 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
2003-03-25 Updated TERM oxidoreductase activity, acting on NADH or NADPH
2003-03-19 Updated TERM oxidoreductase, acting on NADH or NADPH activity
2002-02-06 Updated TERM oxidoreductase, acting on NADH or NADPH
2001-04-03 Updated TERM oxidoreductase, acting on NADH or NADPH
2001-03-30 Added XREF EC:1.6.-.-
2001-03-30 Added TERM oxidoreductase, acting on NADH or NADPH

Term

Timestamp Action Category Detail
2013-01-13 Updated TERM oxidoreductase activity, acting on NAD(P)H
2003-03-25 Updated TERM oxidoreductase activity, acting on NADH or NADPH
2003-03-19 Updated TERM oxidoreductase, acting on NADH or NADPH activity
2002-02-06 Updated TERM oxidoreductase, acting on NADH or NADPH
2001-04-03 Updated TERM oxidoreductase, acting on NADH or NADPH
2001-03-30 Added TERM oxidoreductase, acting on NADH or NADPH

Definition/synonyms

Timestamp Action Category Detail
2013-01-13 Added SYNONYM oxidoreductase activity, acting on NADH or NADPH
2008-05-13 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
2008-05-12 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
2007-08-09 Added SYNONYM NAD(P)H dehydrogenase
2007-08-09 Added SYNONYM oxidoreductase activity, acting on NADH or NADPH, other acceptor
2007-08-09 Deleted SYNONYM NAD(P)H dehydrogenase
2007-08-09 Deleted SYNONYM oxidoreductase activity, acting on NADH or NADPH, other acceptor
2005-08-10 Added SYNONYM NAD(P)H dehydrogenase
2005-08-10 Added SYNONYM oxidoreductase activity, acting on NADH or NADPH, other acceptor
2003-09-25 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016491 (oxidoreductase activity)

Cross-references

Timestamp Action Category Detail
2006-02-09 Added XREF EC:1.6
2006-02-09 Deleted XREF EC:1.6.-.-
2001-03-30 Added XREF EC:1.6.-.-
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