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GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

Term Information

ID GO:0016616
Name oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Ontology Molecular Function
Definition Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
Comment

Cross-references associated with this term:

Database ID
INTERPRO IPR014028
INTERPRO IPR014685
INTERPRO IPR012302
INTERPRO IPR009029
INTERPRO IPR014027
INTERPRO IPR011128
INTERPRO IPR001732
INTERPRO IPR014684
EC 1.1.1
INTERPRO IPR009023
INTERPRO IPR004553
INTERPRO IPR012188
INTERPRO IPR001804
INTERPRO IPR006139
INTERPRO IPR006140
INTERPRO IPR019818
INTERPRO IPR014026
INTERPRO IPR001557
INTERPRO IPR014360
INTERPRO IPR012301

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Ancestor Chart

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Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity
I GO:0004471 malate dehydrogenase (decarboxylating) activity
I GO:0004473 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity
I GO:0050491 sulcatone reductase activity
I GO:0050492 glycerol-1-phosphate dehydrogenase [NAD(P)+] activity
I GO:0000140 acylglycerone-phosphate reductase activity
I GO:0047795 cyclohexane-1,2-diol dehydrogenase activity
I GO:0047813 D-arabinitol 4-dehydrogenase activity
I GO:0047816 D-arabinose 1-dehydrogenase activity
I GO:0047108 (R)-3-hydroxyacid-ester dehydrogenase activity
I GO:0047109 (S)-3-hydroxyacid-ester dehydrogenase activity
I GO:0018451 epoxide dehydrogenase activity
I GO:0018452 5-exo-hydroxycamphor dehydrogenase activity
I GO:0018453 2-hydroxytetrahydrofuran dehydrogenase activity
I GO:0018454 acetoacetyl-CoA reductase activity
I GO:0018456 aryl-alcohol dehydrogenase activity
I GO:0018457 perillyl-alcohol dehydrogenase activity
I GO:0018458 isopiperitenol dehydrogenase activity
I GO:0018459 carveol dehydrogenase activity
I GO:0018460 cyclohexanol dehydrogenase activity
I GO:0018461 fluoren-9-ol dehydrogenase activity
I GO:0018462 4-(hydroxymethyl)benzenesulfonate dehydrogenase activity
I GO:0018463 6-hydroxyhexanoate dehydrogenase activity
I GO:0018464 3-hydroxypimeloyl-CoA dehydrogenase activity
I GO:0045290 D-arabinose 1-dehydrogenase [NAD(P)+] activity
I GO:0042282 hydroxymethylglutaryl-CoA reductase activity
I GO:0016619 malate dehydrogenase (oxaloacetate-decarboxylating) activity
I GO:0030060 L-malate dehydrogenase activity
I GO:0047824 D-iditol 2-dehydrogenase activity
I GO:0047832 D-pinitol dehydrogenase activity
I GO:0047834 D-threo-aldose 1-dehydrogenase activity
I GO:0047837 D-xylose 1-dehydrogenase (NADP+) activity
I GO:0047838 D-xylose 1-dehydrogenase activity
I GO:0047855 dihydrobunolol dehydrogenase activity
I GO:0047860 diiodophenylpyruvate reductase activity
I GO:0047867 dimethylmalate dehydrogenase activity
I GO:0047880 erythrulose reductase activity
I GO:0047886 farnesol dehydrogenase activity
I GO:0047890 flavanone 4-reductase activity
I GO:0047903 fructose 5-dehydrogenase (NADP+) activity
I GO:0047910 galactose 1-dehydrogenase (NADP+) activity
I GO:0047916 GDP-6-deoxy-D-talose 4-dehydrogenase activity
I GO:0047919 GDP-mannose 6-dehydrogenase activity
I GO:0047924 geraniol dehydrogenase activity
I GO:0047500 (+)-borneol dehydrogenase activity
I GO:0047501 (+)-neomenthol dehydrogenase activity
I GO:0047502 (+)-sabinol dehydrogenase activity
I GO:0047503 (-)-borneol dehydrogenase activity
I GO:0047504 (-)-menthol dehydrogenase activity
I GO:0047512 (S,S)-butanediol dehydrogenase activity
I GO:0047516 1,3-propanediol dehydrogenase activity
I GO:0047535 2-alkyn-1-ol dehydrogenase activity
I GO:0047550 2-oxoadipate reductase activity
I GO:0047559 3-dehydro-L-gulonate 2-dehydrogenase activity
I GO:0047560 3-dehydrosphinganine reductase activity
I GO:0047565 3-hydroxypropionate dehydrogenase activity
I GO:0047577 4-hydroxybutyrate dehydrogenase activity
I GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity
I GO:0003858 3-hydroxybutyrate dehydrogenase activity
I GO:0003862 3-isopropylmalate dehydrogenase activity
I GO:0003938 IMP dehydrogenase activity
I GO:0003939 L-iditol 2-dehydrogenase activity
I GO:0003979 UDP-glucose 6-dehydrogenase activity
I GO:0004022 alcohol dehydrogenase (NAD) activity
I GO:0004090 carbonyl reductase (NADPH) activity
I GO:0046029 mannitol dehydrogenase activity
I GO:0047936 glucose 1-dehydrogenase activity
I GO:0047939 L-glucuronate reductase activity
I GO:0047941 glucuronolactone reductase activity
I GO:0047952 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
I GO:0047953 glycerol 2-dehydrogenase (NADP+) activity
I GO:0047956 glycerol dehydrogenase (NADP+) activity
I GO:0047964 glyoxylate reductase activity
I GO:0047978 hexadecanol dehydrogenase activity
I GO:0047993 hydroxymalonate dehydrogenase activity
I GO:0047995 hydroxyphenylpyruvate reductase activity
I GO:0050009 isopropanol dehydrogenase (NADP+) activity
I GO:0050019 L-arabinitol 4-dehydrogenase activity
I GO:0050022 L-arabinose 1-dehydrogenase (NAD+) activity
I GO:0050026 L-glycol dehydrogenase activity
I GO:0050027 L-idonate 2-dehydrogenase activity
I GO:0050034 L-rhamnose 1-dehydrogenase activity
I GO:0050036 L-threonate 3-dehydrogenase activity
I GO:0050037 L-xylose 1-dehydrogenase activity
I GO:0050038 L-xylulose reductase (NADP+) activity
I GO:0050039 lactaldehyde reductase (NADPH) activity
I GO:0050060 long-chain-alcohol dehydrogenase activity
I GO:0050085 mannitol 2-dehydrogenase (NADP+) activity
I GO:0050086 mannitol 2-dehydrogenase activity
I GO:0050088 mannose-6-phosphate 6-reductase activity
I GO:0050090 mannuronate reductase activity
I GO:0050093 methanol dehydrogenase activity
I GO:0050104 L-gulonate 3-dehydrogenase activity
I GO:0050109 morphine 6-dehydrogenase activity
I GO:0050120 N-acetylhexosamine 1-dehydrogenase activity
I GO:0050123 N-acylmannosamine 1-dehydrogenase activity
I GO:0050153 omega-hydroxydecanoate dehydrogenase activity
I GO:0050166 pantoate 4-dehydrogenase activity
I GO:0047599 8-oxocoformycin reductase activity
I GO:0055041 cyclopentanol dehydrogenase activity
I GO:0031132 serine 3-dehydrogenase activity
I GO:0030266 quinate 5-dehydrogenase activity
I GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity
I GO:0043892 methylglyoxal reductase (NADPH-dependent) activity
I GO:0050216 propanediol-phosphate dehydrogenase activity
I GO:0050221 prostaglandin-E2 9-reductase activity
I GO:0050229 pterocarpin synthase activity
I GO:0051903 S-(hydroxymethyl)glutathione dehydrogenase activity
I GO:0046998 (S)-usnate reductase activity
I GO:0047000 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity
I GO:0047001 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity
I GO:0047002 L-arabinitol 2-dehydrogenase activity
I GO:0047003 dTDP-6-deoxy-L-talose 4-dehydrogenase activity
I GO:0047004 UDP-N-acetylglucosamine 6-dehydrogenase activity
I GO:0047009 3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity
I GO:0047010 hydroxycyclohexanecarboxylate dehydrogenase activity
I GO:0047011 2-dehydropantolactone reductase (A-specific) activity
I GO:0047012 sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity
I GO:0047014 glycerol-3-phosphate 1-dehydrogenase (NADP+) activity
I GO:0047015 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity
I GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity
I GO:0047017 prostaglandin-F synthase activity
I GO:0047018 indole-3-acetaldehyde reductase (NADH) activity
I GO:0047019 indole-3-acetaldehyde reductase (NADPH) activity
I GO:0047020 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
I GO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity
I GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity
I GO:0047027 benzyl-2-methyl-hydroxybutyrate dehydrogenase activity
I GO:0047028 6-pyruvoyltetrahydropterin 2'-reductase activity
I GO:0047029 (R)-4-hydroxyphenyllactate dehydrogenase activity
I GO:0047030 4-hydroxycyclohexanecarboxylate dehydrogenase activity
I GO:0047031 diethyl 2-methyl-3-oxosuccinate reductase activity
I GO:0047032 3-alpha-hydroxyglycyrrhetinate dehydrogenase activity
I GO:0047033 15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity
I GO:0047034 15-hydroxyicosatetraenoate dehydrogenase activity
I GO:0047036 codeinone reductase (NADPH) activity
I GO:0047037 salutaridine reductase (NADPH) activity
I GO:0047038 D-arabinitol 2-dehydrogenase activity
I GO:0047039 tetrahydroxynaphthalene reductase activity
I GO:0047041 (S)-carnitine 3-dehydrogenase activity
I GO:0047043 3-alpha-hydroxycholanate dehydrogenase activity
I GO:0047046 homoisocitrate dehydrogenase activity
I GO:0047047 oxaloglycolate reductase (decarboxylating) activity
I GO:0047048 3-hydroxybenzyl-alcohol dehydrogenase activity
I GO:0047049 (R)-2-hydroxy-fatty-acid dehydrogenase activity
I GO:0047050 (S)-2-hydroxy-fatty-acid dehydrogenase activity
I GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase activity
I GO:0004345 glucose-6-phosphate dehydrogenase activity
I GO:0004367 glycerol-3-phosphate dehydrogenase (NAD+) activity
I GO:0004399 histidinol dehydrogenase activity
I GO:0004412 homoserine dehydrogenase activity
I GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity
I GO:0004448 isocitrate dehydrogenase activity
I GO:0004455 ketol-acid reductoisomerase activity
I GO:0004459 L-lactate dehydrogenase activity
I GO:0008114 phosphogluconate 2-dehydrogenase activity
I GO:0050235 pyridoxal 4-dehydrogenase activity
I GO:0050255 ribitol 2-dehydrogenase activity
I GO:0050256 ribitol-5-phosphate 2-dehydrogenase activity
I GO:0050259 ribose 1-dehydrogenase (NADP+) activity
I GO:0050268 coniferyl-alcohol dehydrogenase activity
I GO:0050280 sequoyitol dehydrogenase activity
I GO:0050287 sorbose 5-dehydrogenase (NADP+) activity
I GO:0050356 tropine dehydrogenase activity
I GO:0050358 tropinone reductase activity
I GO:0050388 uronate dehydrogenase activity
I GO:0050396 vomifoliol 4'-dehydrogenase activity
I GO:0019141 2-dehydropantolactone reductase (B-specific) activity
I GO:0019147 (R)-aminopropanol dehydrogenase activity
I GO:0019151 galactose 1-dehydrogenase activity
I GO:0019152 acetoin dehydrogenase activity
I GO:0019155 3-(imidazol-5-yl)lactate dehydrogenase activity
I GO:0019170 methylglyoxal reductase (NADH-dependent) activity
I GO:0030267 glyoxylate reductase (NADP) activity
I GO:0047640 aldose 1-dehydrogenase activity
I GO:0047641 aldose-6-phosphate reductase (NADPH) activity
I GO:0047655 allyl-alcohol dehydrogenase activity
I GO:0050570 4-hydroxythreonine-4-phosphate dehydrogenase activity
I GO:0050571 1,5-anhydro-D-fructose reductase activity
I GO:0050572 L-idonate 5-dehydrogenase activity
I GO:0050573 dTDP-4-dehydro-6-deoxyglucose reductase activity
I GO:0050574 2-(R)-hydroxypropyl-CoM dehydrogenase activity
I GO:0050575 2-(S)-hydroxypropyl-CoM dehydrogenase activity
I GO:0050577 GDP-L-fucose synthase activity
I GO:0050578 (R)-2-hydroxyacid dehydrogenase activity
I GO:0050579 vellosimine dehydrogenase activity
I GO:0050580 2,5-didehydrogluconate reductase activity
I GO:0008678 2-deoxy-D-gluconate 3-dehydrogenase activity
I GO:0008679 2-hydroxy-3-oxopropionate reductase activity
I GO:0008691 3-hydroxybutyryl-CoA dehydrogenase activity
I GO:0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity
I GO:0008720 D-lactate dehydrogenase activity
I GO:0008743 L-threonine 3-dehydrogenase activity
I GO:0008762 UDP-N-acetylmuramate dehydrogenase activity
I GO:0008831 dTDP-4-dehydrorhamnose reductase activity
I GO:0008866 fructuronate reductase activity
I GO:0008868 galactitol-1-phosphate 5-dehydrogenase activity
I GO:0008875 gluconate dehydrogenase activity
I GO:0008888 glycerol dehydrogenase activity
I GO:0008912 lactaldehyde reductase activity
I GO:0008926 mannitol-1-phosphate 5-dehydrogenase activity
I GO:0030604 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
I GO:0004552 octanol dehydrogenase activity
I GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity
I GO:0004617 phosphoglycerate dehydrogenase activity
I GO:0047674 apiose 1-reductase activity
I GO:0047681 aryl-alcohol dehydrogenase (NADP+) activity
I GO:0047728 carnitine 3-dehydrogenase activity
I GO:0047743 chlordecone reductase activity
I GO:0047748 cholestanetetraol 26-dehydrogenase activity
I GO:0047713 galactitol 2-dehydrogenase activity
I GO:0047718 indanol dehydrogenase activity
I GO:0047722 indolelactate dehydrogenase activity
I GO:0004745 retinol dehydrogenase activity
I GO:0004757 sepiapterin reductase activity
I GO:0004764 shikimate 5-dehydrogenase activity
I GO:0004033 aldo-keto reductase activity
I GO:0018455 alcohol dehydrogenase [NAD(P)+] activity
I GO:0008442 3-hydroxyisobutyrate dehydrogenase activity
I GO:0008465 glycerate dehydrogenase activity
I GO:0008677 2-dehydropantoate 2-reductase activity
I GO:0045481 6-endo-hydroxycineole dehydrogenase activity
I GO:0000721 (R,R)-butanediol dehydrogenase activity
I GO:0009010 sorbitol-6-phosphate 2-dehydrogenase activity
I GO:0009026 tagaturonate reductase activity
I GO:0009027 tartrate dehydrogenase activity
I GO:0009040 ureidoglycolate dehydrogenase activity
I GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity
I GO:0032442 phenylcoumaran benzylic ether reductase activity
I GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
I GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
I GO:0000253 3-keto sterol reductase activity
I GO:0004495 mevaldate reductase activity
I GO:0045551 cinnamyl-alcohol dehydrogenase activity
I GO:0045552 dihydrokaempferol 4-reductase activity
I GO:0048258 3-ketoglucose-reductase activity
I GO:0046526 D-xylulose reductase activity
I GO:0046553 D-malate dehydrogenase (decarboxylating) activity
I GO:0046554 malate dehydrogenase (NADP+) activity
I GO:0016617 4-oxoproline reductase activity
I GO:0016618 hydroxypyruvate reductase activity
I GO:0044103 L-arabinose 1-dehydrogenase (NADP+) activity
I GO:0044105 L-xylulose reductase (NAD+) activity
I GO:0010490 UDP-4-keto-rhamnose-4-keto-reductase activity
I GO:0032115 sorbose reductase activity
I GO:0033019 5-hydroxyvalerate dehydrogenase activity
I GO:0033790 hydroxymethylfurfural reductase activity
I GO:0033701 dTDP-galactose 6-dehydrogenase activity
I GO:0033702 (+)-trans-carveol dehydrogenase activity
I GO:0033703 3beta-hydroxy-5beta-steroid dehydrogenase activity
I GO:0033704 3beta-hydroxy-5alpha-steroid dehydrogenase activity
I GO:0033705 GDP-4-dehydro-6-deoxy-D-mannose reductase activity
I GO:0033706 quinate/shikimate dehydrogenase activity
I GO:0033707 3''-deamino-3''-oxonicotianamine reductase activity
I GO:0033708 isocitrate-homoisocitrate dehydrogenase activity
I GO:0033709 D-arabinitol dehydrogenase (NADP+) activity
I GO:0033711 4-phosphoerythronate dehydrogenase activity
I GO:0033712 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity
I GO:0034831 (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity
I GO:0034840 3-hydroxymenthone dehydrogenase activity
I GO:0034256 chlorophyll(ide) b reductase activity
I GO:0043713 (R)-2-hydroxyisocaproate dehydrogenase activity
I GO:0043718 2-hydroxymethylglutarate dehydrogenase activity

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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