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GO:0016591 DNA-directed RNA polymerase II, holoenzyme

Term Information

ID GO:0016591
Name DNA-directed RNA polymerase II, holoenzyme
Ontology Cellular Component
Definition Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA.
PMID:15196470
GONUTS GO:0016591 Wiki Page

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000059 GO:0005634 nucleus only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_pir462

Cross-references

Database ID
InterPro IPR023598
InterPro IPR026213

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016591:
Relationship To GO:0016591 Child Term Child Term Name
Part of GO:0032039 integrator complex
Part of GO:0016593 Cdc73/Paf1 complex
Part of GO:0005665 DNA-directed RNA polymerase II, core complex
Part of GO:0005669 transcription factor TFIID complex
Part of GO:0005672 transcription factor TFIIA complex
Part of GO:0005673 transcription factor TFIIE complex
Part of GO:0005674 transcription factor TFIIF complex
Part of GO:0005675 holo TFIIH complex
Part of GO:0070264 transcription factor TFIIIE complex
Part of GO:0070847 core mediator complex
Part of GO:0033276 transcription factor TFTC complex
Part of GO:0034740 TFIIIC-TOP1-SUB1 complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
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Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016591. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016591 based on the entire annotation set Co-occurrence statistics for GO:0016591 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2012-07-13 Added RELATION is a GO:0055029 (nuclear DNA-directed RNA polymerase complex)
2012-07-13 Deleted RELATION is a GO:0043234 (protein complex)
2008-06-09 Added SLIM goslim_pir
2008-05-13 Added DEFINITION Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA.
2008-05-12 Deleted DEFINITION Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA.
2008-04-01 Updated RELATION is a GO:0044451 (nucleoplasm part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2004-11-09 Added DEFINITION Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA.
2002-02-06 Updated TERM DNA-directed RNA polymerase II, holoenzyme
2001-04-03 Updated TERM DNA-directed RNA polymerase II, holoenzyme
2001-03-30 Added TERM DNA-directed RNA polymerase II, holoenzyme

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM DNA-directed RNA polymerase II, holoenzyme
2001-04-03 Updated TERM DNA-directed RNA polymerase II, holoenzyme
2001-03-30 Added TERM DNA-directed RNA polymerase II, holoenzyme

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA.
2008-05-12 Deleted DEFINITION Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA.
2004-11-09 Added DEFINITION Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA.

Relationships

Timestamp Action Category Detail
2012-07-13 Added RELATION is a GO:0055029 (nuclear DNA-directed RNA polymerase complex)
2012-07-13 Deleted RELATION is a GO:0043234 (protein complex)
2008-04-01 Updated RELATION is a GO:0044451 (nucleoplasm part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2008-06-09 Added SLIM goslim_pir
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