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GO:0016591 DNA-directed RNA polymerase II, holoenzyme

Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA.

Term Information

ID GO:0016591
Name DNA-directed RNA polymerase II, holoenzyme
Ontology Cellular Component
Definition Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA.
Comment

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_pir469

Web service: term information

Use this URI template to access this data as a service:

GTerm?id=termID&format=format

Full details can be found on the QuickGO Web Services page.

Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0005575 cellular_component
GO:0005623 cell
GO:0043226 organelle
GO:0032991 macromolecular complex
GO:0031974 membrane-enclosed lumen
GO:0043234 protein complex
GO:0044422 organelle part
GO:0043227 membrane-bounded organelle
GO:0044464 cell part
GO:0005622 intracellular
GO:0044424 intracellular part
GO:0043233 organelle lumen
GO:0043229 intracellular organelle
GO:0044446 intracellular organelle part
GO:0043231 intracellular membrane-bounded organelle
GO:0005634 nucleus
GO:0070013 intracellular organelle lumen
GO:0044428 nuclear part
GO:0031981 nuclear lumen
GO:0005654 nucleoplasm
GO:0044451 nucleoplasm part
GO:0016591 DNA-directed RNA polymerase II, holoenzyme

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
P GO:0032039 integrator complex
P GO:0016593 Cdc73/Paf1 complex
P GO:0005665 DNA-directed RNA polymerase II, core complex
P GO:0005669 transcription factor TFIID complex
P GO:0005672 transcription factor TFIIA complex
P GO:0005673 transcription factor TFIIE complex
P GO:0005674 transcription factor TFIIF complex
P GO:0005675 holo TFIIH complex
P GO:0070264 transcription factor TFIIIE complex
P GO:0070847 core mediator complex
P GO:0033276 transcription factor TFTC complex
P GO:0034740 TFIIIC-TOP1-SUB1 complex

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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13ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-12-16-04-01-54
Terminal
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