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GO:0016564 transcription repressor activity

This term is obsolete.
This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.

Term Information

ID GO:0016564
Name transcription repressor activity
Ontology Molecular Function
Definition OBSOLETE. Any transcription regulator activity that prevents or downregulates transcription.
Comment This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.
GONUTS GO:0016564 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact negative transcriptional regulator activity
exact transcriptional repressor activity

Replaced by

This term is obsolete - try one of these terms:
Advice GO Identifier Ontology GO Term Name
Consider GO:0000988 Molecular Function protein binding transcription factor activity
Consider GO:0001071 Molecular Function nucleic acid binding transcription factor activity
Consider GO:0045892 Biological Process negative regulation of transcription, DNA-templated

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016564:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016564. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016564 based on the entire annotation set Co-occurrence statistics for GO:0016564 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-05-20 Deleted OBSOLETION consider GO:0045893 (positive regulation of transcription, DNA-templated)
2011-05-20 Added OBSOLETION consider GO:0045892 (negative regulation of transcription, DNA-templated)
2011-05-16 Added OBSOLETION consider GO:0045893 (positive regulation of transcription, DNA-templated)
2011-05-16 Added OBSOLETION consider GO:0000988 (protein binding transcription factor activity)
2011-05-16 Added OBSOLETION consider GO:0001071 (nucleic acid binding transcription factor activity)
2011-05-16 Added DEFINITION OBSOLETE. Any transcription regulator activity that prevents or downregulates transcription.
2011-05-16 Deleted RELATION is a GO:0030528 (transcription regulator activity)
2011-05-16 Updated TERM transcription repressor activity
2011-05-16 Deleted DEFINITION Any transcription regulator activity that prevents or downregulates transcription.
2011-03-18 Deleted RELATION part of GO:0016481 (negative regulation of transcription)
2010-06-15 Added RELATION part of GO:0016481 (negative regulation of transcription)
2010-06-14 Deleted RELATION part of GO:0016481 (negative regulation of transcription)
2010-06-08 Added RELATION part of GO:0016481 (negative regulation of transcription)
2008-05-13 Added DEFINITION Any transcription regulator activity that prevents or downregulates transcription.
2008-05-12 Deleted DEFINITION Any transcription regulator activity that prevents or downregulates transcription.
2008-04-01 Updated RELATION is a GO:0030528 (transcription regulator activity)
2007-08-09 Added SYNONYM negative transcriptional regulator activity
2007-08-09 Added SYNONYM transcriptional repressor activity
2007-08-09 Deleted SYNONYM negative transcriptional regulator activity
2007-08-09 Deleted SYNONYM transcriptional repressor activity
2007-07-22 Updated TERM transcription repressor activity
2007-07-22 Added SYNONYM transcriptional repressor activity
2007-06-23 Added SYNONYM negative transcriptional regulator activity
2006-10-21 Added DEFINITION Any transcription regulator activity that prevents or downregulates transcription.
2003-03-19 Updated TERM transcriptional repressor activity
2002-02-06 Updated TERM transcriptional repressor
2001-04-03 Updated TERM transcriptional repressor
2001-03-30 Added TERM transcriptional repressor

Term

Timestamp Action Category Detail
2011-05-16 Updated TERM transcription repressor activity
2007-07-22 Updated TERM transcription repressor activity
2003-03-19 Updated TERM transcriptional repressor activity
2002-02-06 Updated TERM transcriptional repressor
2001-04-03 Updated TERM transcriptional repressor
2001-03-30 Added TERM transcriptional repressor

Obsoletions

Timestamp Action Category Detail
2011-05-20 Deleted OBSOLETION consider GO:0045893 (positive regulation of transcription, DNA-templated)
2011-05-20 Added OBSOLETION consider GO:0045892 (negative regulation of transcription, DNA-templated)
2011-05-16 Added OBSOLETION consider GO:0045893 (positive regulation of transcription, DNA-templated)
2011-05-16 Added OBSOLETION consider GO:0000988 (protein binding transcription factor activity)
2011-05-16 Added OBSOLETION consider GO:0001071 (nucleic acid binding transcription factor activity)

Definition/synonyms

Timestamp Action Category Detail
2011-05-16 Added DEFINITION OBSOLETE. Any transcription regulator activity that prevents or downregulates transcription.
2011-05-16 Deleted DEFINITION Any transcription regulator activity that prevents or downregulates transcription.
2008-05-13 Added DEFINITION Any transcription regulator activity that prevents or downregulates transcription.
2008-05-12 Deleted DEFINITION Any transcription regulator activity that prevents or downregulates transcription.
2007-08-09 Added SYNONYM negative transcriptional regulator activity
2007-08-09 Added SYNONYM transcriptional repressor activity
2007-08-09 Deleted SYNONYM negative transcriptional regulator activity
2007-08-09 Deleted SYNONYM transcriptional repressor activity
2007-07-22 Added SYNONYM transcriptional repressor activity
2007-06-23 Added SYNONYM negative transcriptional regulator activity
2006-10-21 Added DEFINITION Any transcription regulator activity that prevents or downregulates transcription.

Relationships

Timestamp Action Category Detail
2011-05-16 Deleted RELATION is a GO:0030528 (transcription regulator activity)
2011-03-18 Deleted RELATION part of GO:0016481 (negative regulation of transcription)
2010-06-15 Added RELATION part of GO:0016481 (negative regulation of transcription)
2010-06-14 Deleted RELATION part of GO:0016481 (negative regulation of transcription)
2010-06-08 Added RELATION part of GO:0016481 (negative regulation of transcription)
2008-04-01 Updated RELATION is a GO:0030528 (transcription regulator activity)
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