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GO:0016491 oxidoreductase activity

Term Information

ID GO:0016491
Name oxidoreductase activity
Ontology Molecular Function
Definition Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
Comment Note that enzymes of class EC:1.97.-.- should also be annotated to this term.
GONUTS GO:0016491 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact redox activity
narrow oxidoreductase activity, acting on other substrates

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_metagenomics119
goslim_generic149
goslim_candida89
goslim_pir462
goslim_yeast169
goslim_aspergillus85

Cross-references

Database ID
EC 1
InterPro IPR000103
InterPro IPR000262
InterPro IPR000392
InterPro IPR000415
InterPro IPR000510
InterPro IPR000683
InterPro IPR000778
InterPro IPR000815
InterPro IPR000866
InterPro IPR000951
InterPro IPR001100
InterPro IPR001117
InterPro IPR001155
InterPro IPR001203
InterPro IPR001236
InterPro IPR001327
InterPro IPR001433
InterPro IPR001613
InterPro IPR001670
InterPro IPR001709
InterPro IPR001834
InterPro IPR001989
InterPro IPR002023
InterPro IPR002057
InterPro IPR002085
InterPro IPR002198
InterPro IPR002227
InterPro IPR002283
InterPro IPR002328
InterPro IPR002346
InterPro IPR002364
InterPro IPR002427
InterPro IPR002489
InterPro IPR002563
InterPro IPR002742
InterPro IPR002811
InterPro IPR002812
InterPro IPR002869
InterPro IPR002880
InterPro IPR002888
InterPro IPR002937
InterPro IPR003042
InterPro IPR003097
InterPro IPR003251
InterPro IPR003421
InterPro IPR003710
InterPro IPR003767
InterPro IPR003819
InterPro IPR003952
InterPro IPR004104
InterPro IPR004137
InterPro IPR004183
InterPro IPR004378
InterPro IPR004453
InterPro IPR004489
InterPro IPR004652
InterPro IPR004653
InterPro IPR004660
InterPro IPR004852
InterPro IPR005025
InterPro IPR005066
InterPro IPR005097
InterPro IPR005106
InterPro IPR005117
InterPro IPR005123
InterPro IPR005797
InterPro IPR005798
InterPro IPR005803
InterPro IPR005884
InterPro IPR005903
InterPro IPR005992
InterPro IPR006066
InterPro IPR006067
InterPro IPR006076
InterPro IPR006093
InterPro IPR006094
InterPro IPR006095
InterPro IPR006096
InterPro IPR006097
InterPro IPR006108
InterPro IPR006176
InterPro IPR006180
InterPro IPR006401
InterPro IPR006655
InterPro IPR006656
InterPro IPR006657
InterPro IPR006658
InterPro IPR006694
InterPro IPR006963
InterPro IPR008142
InterPro IPR008143
InterPro IPR008254
InterPro IPR008255
InterPro IPR008259
InterPro IPR008274
InterPro IPR008335
InterPro IPR010758
InterPro IPR010791
InterPro IPR011254
InterPro IPR011706
InterPro IPR012133
InterPro IPR012348
InterPro IPR012349
InterPro IPR012727
InterPro IPR012833
InterPro IPR012839
InterPro IPR012882
InterPro IPR012951
InterPro IPR013023
InterPro IPR013112
InterPro IPR013118
InterPro IPR013121
InterPro IPR013131
InterPro IPR013149
InterPro IPR013154
InterPro IPR013328
InterPro IPR013580
InterPro IPR013740
InterPro IPR013752
InterPro IPR013983
InterPro IPR014184
InterPro IPR014222
InterPro IPR014313
InterPro IPR014430
InterPro IPR015590
InterPro IPR015701
InterPro IPR015815
InterPro IPR015845
InterPro IPR015875
InterPro IPR015939
InterPro IPR016156
InterPro IPR016160
InterPro IPR016161
InterPro IPR016162
InterPro IPR016163
InterPro IPR016208
InterPro IPR016440
InterPro IPR016446
InterPro IPR017224
InterPro IPR017840
InterPro IPR017927
InterPro IPR017938
InterPro IPR017941
InterPro IPR018170
InterPro IPR018211
InterPro IPR019574
InterPro IPR020471
InterPro IPR020843
InterPro IPR020904
InterPro IPR021163
InterPro IPR021179
InterPro IPR022394
InterPro IPR023173
InterPro IPR023643
InterPro IPR023753
InterPro IPR023867
InterPro IPR023936
InterPro IPR024036
InterPro IPR026259
InterPro IPR027052
InterPro IPR027496
InterPro IPR028836
InterPro IPR029510
UniProtKB-KW Oxidoreductase

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0006118 electron transport CONSIDER GO:0016491
GO:0016739 oxidoreductase activity, acting on other substrates CONSIDER GO:0016491
GO:0016164 Mo-molybdopterin oxidoreductase activity REPLACEDBY GO:0016491

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016491:
Relationship To GO:0016491 Child Term Child Term Name
Is a GO:0051213 dioxygenase activity
Is a GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors
Is a GO:0051744 3,8-divinyl protochlorophyllide a 8-vinyl reductase activity
Is a GO:0045301 tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity
Is a GO:0043871 delta1-piperideine-6-carboxylate dehydrogenase activity
Is a GO:0000170 sphingosine hydroxylase activity
Is a GO:0001512 dihydronicotinamide riboside quinone reductase activity
Is a GO:0003826 alpha-ketoacid dehydrogenase activity
Is a GO:0004154 dihydropterin oxidase activity
Is a GO:0004497 monooxygenase activity
Is a GO:0004836 tyramine-beta hydroxylase activity
Is a GO:0008682 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity
Is a GO:0008748 N-ethylmaleimide reductase activity
Is a GO:0015002 heme-copper terminal oxidase activity
Is a GO:0019168 2-octaprenylphenol hydroxylase activity
Is a GO:0019174 tetrahydrothiophene 1-oxide reductase activity
Is a GO:0042380 hydroxymethylbutenyl pyrophosphate reductase activity
Is a GO:0004800 thyroxine 5'-deiodinase activity
Is a GO:0018698 vinyl chloride reductive dehalogenase activity
Is a GO:0018699 1,1,1-trichloroethane reductive dehalogenase activity
Is a GO:0018700 2-chloro-N-isopropylacetanilide reductive dehalogenase activity
Is a GO:0018701 2,5-dichlorohydroquinone reductive dehalogenase activity
Is a GO:0018702 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity
Is a GO:0018703 2,4-dichlorophenoxyacetate dehalogenase activity
Is a GO:0018705 1,2-dichloroethene reductive dehalogenase activity
Is a GO:0018706 pyrogallol hydroxytransferase activity
Is a GO:0016229 steroid dehydrogenase activity
Is a GO:0043914 NADPH:sulfur oxidoreductase activity
Is a GO:0030611 arsenate reductase activity
Is a GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors
Is a GO:0010242 oxygen evolving activity
Is a GO:0043365 [formate-C-acetyltransferase]-activating enzyme activity
Is a GO:0047143 chlorate reductase activity
Is a GO:0045550 geranylgeranyl reductase activity
Is a GO:0050629 tetrachloroethene reductive dehalogenase activity
Is a GO:0050697 1,1,2-trichloroethene reductive dehalogenase activity
Is a GO:0050781 ortho-trichlorophenol reductive dehalogenase activity
Is a GO:0046992 oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond
Is a GO:0046422 violaxanthin de-epoxidase activity
Is a GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Is a GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
Is a GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
Is a GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors
Is a GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors
Is a GO:0016651 oxidoreductase activity, acting on NAD(P)H
Is a GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors
Is a GO:0016667 oxidoreductase activity, acting on a sulfur group of donors
Is a GO:0016675 oxidoreductase activity, acting on a heme group of donors
Is a GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors
Is a GO:0016684 oxidoreductase activity, acting on peroxide as acceptor
Is a GO:0016695 oxidoreductase activity, acting on hydrogen as donor
Is a GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
Is a GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor
Is a GO:0016722 oxidoreductase activity, oxidizing metal ions
Is a GO:0016725 oxidoreductase activity, acting on CH or CH2 groups
Is a GO:0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors
Is a GO:0016737 oxidoreductase activity, acting on reduced flavodoxin as donor
Is a GO:0035515 oxidative RNA demethylase activity
Is a GO:0035516 oxidative DNA demethylase activity
Regulates GO:0051341 regulation of oxidoreductase activity
Positively regulates GO:0051353 positive regulation of oxidoreductase activity
Negatively regulates GO:0051354 negative regulation of oxidoreductase activity
Is a GO:0052614 uracil oxygenase activity
Is a GO:0043826 sulfur oxygenase reductase activity
Is a GO:0070643 vitamin D 25-hydroxylase activity
Is a GO:0080132 fatty acid alpha-hydroxylase activity
Is a GO:0034937 perchlorate reductase activity
Is a GO:0034949 1,1-dichloroethane reductive dehalogenase activity
Is a GO:0052583 oxidoreductase activity, acting on halogen in donors
Is a GO:0043880 crotonyl-CoA reductase activity
Is a GO:0043883 malolactic enzyme activity
Is a GO:0015039 NADPH-adrenodoxin reductase activity
Is a GO:0015048 phthalate dioxygenase reductase activity
Is a GO:0034539 3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity
Is a GO:0034540 3-monobromobisphenol A reductive dehalogenase activity
Is a GO:0034542 trimethylarsine oxidase activity
Is a GO:0034546 2,4-dichloroaniline reductive dehalogenase activity
Is a GO:0034550 dimethylarsinate reductase activity
Is a GO:0043738 reduced coenzyme F420 dehydrogenase activity
Is a GO:0070576 vitamin D 24-hydroxylase activity
Is a GO:0034554 3,3',5-tribromobisphenol A reductive dehalogenase activity
Is a GO:0034555 3,3'-dibromobisphenol A reductive dehalogenase activity
Is a GO:0034567 chromate reductase activity
Is a GO:0033796 sulfur reductase activity
Is a GO:0033797 selenate reductase activity
Is a GO:0033798 thyroxine 5-deiodinase activity
Is a GO:0052765 reduced coenzyme F420 oxidase activity
Is a GO:0052693 epoxyqueuosine reductase activity
Is a GO:0052755 reduced coenzyme F420:quinone oxidoreductase activity
Is a GO:0036354 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016491. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016491 based on the entire annotation set Co-occurrence statistics for GO:0016491 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_aspergillus
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_candida
2013-04-18 Updated SLIM goslim_generic
2013-04-18 Updated SLIM goslim_metagenomics
2012-02-17 Added SLIM goslim_metagenomics
2012-02-10 Added SLIM goslim_generic
2011-11-05 Added SLIM goslim_aspergillus
2011-04-21 Added RELATION part of GO:0055114 (oxidation-reduction process)
2011-03-18 Deleted SLIM goslim_goa
2008-06-09 Added SLIM goslim_yeast
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_goa
2008-06-09 Added SLIM goslim_candida
2008-05-13 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
2008-05-12 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
2008-04-01 Updated RELATION is a GO:0003824 (catalytic activity)
2007-08-09 Added SYNONYM oxidoreductase activity, acting on other substrates
2007-08-09 Added SYNONYM redox activity
2007-08-09 Deleted SYNONYM oxidoreductase activity, acting on other substrates
2007-08-09 Deleted SYNONYM redox activity
2006-02-09 Added XREF EC:1
2006-02-09 Deleted XREF EC:1.-.-.-
2005-08-10 Added SYNONYM oxidoreductase activity, acting on other substrates
2004-09-29 Updated TERM oxidoreductase activity
2004-07-22 Added SYNONYM redox activity
2003-09-23 Updated DEFINITION Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
2003-03-19 Updated TERM oxidoreductase activity
2002-11-27 Added DEFINITION Catalysis of oxidation-reduction (redox) reactions. Oxidoreductase is the systematic name for any enzyme of class EC 1, which comprises dehydrogenases, hydroxylases, oxidases, and reductases.
2002-02-06 Updated TERM oxidoreductase
2001-04-03 Updated TERM oxidoreductase
2001-03-30 Added XREF EC:1.-.-.-
2001-03-30 Added TERM oxidoreductase

Term

Timestamp Action Category Detail
2004-09-29 Updated TERM oxidoreductase activity
2003-03-19 Updated TERM oxidoreductase activity
2002-02-06 Updated TERM oxidoreductase
2001-04-03 Updated TERM oxidoreductase
2001-03-30 Added TERM oxidoreductase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
2008-05-12 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
2007-08-09 Added SYNONYM oxidoreductase activity, acting on other substrates
2007-08-09 Added SYNONYM redox activity
2007-08-09 Deleted SYNONYM oxidoreductase activity, acting on other substrates
2007-08-09 Deleted SYNONYM redox activity
2005-08-10 Added SYNONYM oxidoreductase activity, acting on other substrates
2004-07-22 Added SYNONYM redox activity
2003-09-23 Updated DEFINITION Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
2002-11-27 Added DEFINITION Catalysis of oxidation-reduction (redox) reactions. Oxidoreductase is the systematic name for any enzyme of class EC 1, which comprises dehydrogenases, hydroxylases, oxidases, and reductases.

Relationships

Timestamp Action Category Detail
2011-04-21 Added RELATION part of GO:0055114 (oxidation-reduction process)
2008-04-01 Updated RELATION is a GO:0003824 (catalytic activity)

Cross-references

Timestamp Action Category Detail
2006-02-09 Added XREF EC:1
2006-02-09 Deleted XREF EC:1.-.-.-
2001-03-30 Added XREF EC:1.-.-.-

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_aspergillus
2013-04-18 Updated SLIM goslim_yeast
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_candida
2013-04-18 Updated SLIM goslim_generic
2013-04-18 Updated SLIM goslim_metagenomics
2012-02-17 Added SLIM goslim_metagenomics
2012-02-10 Added SLIM goslim_generic
2011-11-05 Added SLIM goslim_aspergillus
2011-03-18 Deleted SLIM goslim_goa
2008-06-09 Added SLIM goslim_yeast
2008-06-09 Added SLIM goslim_pir
2008-06-09 Added SLIM goslim_goa
2008-06-09 Added SLIM goslim_candida
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