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GO:0016469 proton-transporting two-sector ATPase complex

Term Information

ID GO:0016469
Name proton-transporting two-sector ATPase complex
Ontology Cellular Component
Definition A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.
PMID:16691483
GONUTS GO:0016469 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact hydrogen-transporting two-sector ATPase complex
related vacuolar hydrogen-transporting ATPase

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_metagenomics119
goslim_pir462

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0000219 vacuolar hydrogen-transporting ATPase CONSIDER GO:0016469

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016469:
Relationship To GO:0016469 Child Term Child Term Name
Is a GO:0033176 proton-transporting V-type ATPase complex
Part of GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain
Part of GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain
Is a GO:0045259 proton-transporting ATP synthase complex

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016469. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016469 based on the entire annotation set Co-occurrence statistics for GO:0016469 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_metagenomics
2012-02-17 Added SLIM goslim_metagenomics
2008-06-09 Added SLIM goslim_pir
2008-05-13 Added DEFINITION A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.
2008-05-12 Deleted DEFINITION A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.
2008-04-01 Updated RELATION is a GO:0044425 (membrane part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2007-08-09 Added SYNONYM hydrogen-transporting two-sector ATPase complex
2007-08-09 Added SYNONYM vacuolar hydrogen-transporting ATPase
2007-08-09 Deleted SYNONYM hydrogen-transporting two-sector ATPase complex
2007-08-09 Deleted SYNONYM vacuolar hydrogen-transporting ATPase
2007-05-27 Updated DEFINITION A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.
2005-08-10 Added SYNONYM vacuolar hydrogen-transporting ATPase
2004-04-19 Added SYNONYM hydrogen-transporting two-sector ATPase complex
2004-04-16 Deleted SYNONYM hydrogen-transporting two-sector ATPase complex
2003-04-12 Added SYNONYM hydrogen-transporting two-sector ATPase complex
2003-04-12 Updated TERM proton-transporting two-sector ATPase complex
2002-11-27 Updated DEFINITION A multisubunit non-phosphorylated ATPase that is involved in the transport of ions. Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (F0, V0, A0) and a cytoplasmic compartment sector (F1, V1, A1). The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases. All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient. The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archebacterial) enzymes have a similar structure but, under physiological conditions, they pump hydrogen ion rather than synthesize ATP.
2002-07-23 Updated TERM hydrogen-transporting two-sector ATPase complex
2002-02-06 Updated TERM hydrogen-transporting two-sector ATPase
2001-08-06 Added DEFINITION A multisubunit non-phosphorylated ATPase that is involved in the transport of ions. Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1). The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases. All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 a- and 3 b-subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g- and e-subunits, as well as the 9-12 c subunits rotate by consecutive 120? angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient. The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archebacterial) enzymes have a similar structure but, under physiological conditions, they pump hydrogen ion rather than synthesize ATP.
2001-04-03 Updated TERM hydrogen-transporting two-sector ATPase
2001-03-30 Added TERM hydrogen-transporting two-sector ATPase

Term

Timestamp Action Category Detail
2003-04-12 Updated TERM proton-transporting two-sector ATPase complex
2002-07-23 Updated TERM hydrogen-transporting two-sector ATPase complex
2002-02-06 Updated TERM hydrogen-transporting two-sector ATPase
2001-04-03 Updated TERM hydrogen-transporting two-sector ATPase
2001-03-30 Added TERM hydrogen-transporting two-sector ATPase

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.
2008-05-12 Deleted DEFINITION A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.
2007-08-09 Added SYNONYM hydrogen-transporting two-sector ATPase complex
2007-08-09 Added SYNONYM vacuolar hydrogen-transporting ATPase
2007-08-09 Deleted SYNONYM hydrogen-transporting two-sector ATPase complex
2007-08-09 Deleted SYNONYM vacuolar hydrogen-transporting ATPase
2007-05-27 Updated DEFINITION A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.
2005-08-10 Added SYNONYM vacuolar hydrogen-transporting ATPase
2004-04-19 Added SYNONYM hydrogen-transporting two-sector ATPase complex
2004-04-16 Deleted SYNONYM hydrogen-transporting two-sector ATPase complex
2003-04-12 Added SYNONYM hydrogen-transporting two-sector ATPase complex
2002-11-27 Updated DEFINITION A multisubunit non-phosphorylated ATPase that is involved in the transport of ions. Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (F0, V0, A0) and a cytoplasmic compartment sector (F1, V1, A1). The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases. All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient. The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archebacterial) enzymes have a similar structure but, under physiological conditions, they pump hydrogen ion rather than synthesize ATP.
2001-08-06 Added DEFINITION A multisubunit non-phosphorylated ATPase that is involved in the transport of ions. Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1). The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases. All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 a- and 3 b-subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g- and e-subunits, as well as the 9-12 c subunits rotate by consecutive 120? angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient. The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archebacterial) enzymes have a similar structure but, under physiological conditions, they pump hydrogen ion rather than synthesize ATP.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0044425 (membrane part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2013-04-18 Updated SLIM goslim_metagenomics
2012-02-17 Added SLIM goslim_metagenomics
2008-06-09 Added SLIM goslim_pir
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