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GO:0016458 gene silencing

Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.

Term Information

ID GO:0016458
Name gene silencing
Ontology Biological Process
Definition Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.
Comment Note that this process is the opposite of long-term maintenance of gene activation.

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_pir469

Synonyms

Type Synonym
related long-term maintenance of gene inactivation

Cross-references associated with this term:

Database ID
INTERPRO IPR018972
Wikipedia Gene_silencing

Web service: term information

Use this URI template to access this data as a service:

GTerm?id=termID&format=format

Full details can be found on the QuickGO Web Services page.

Ancestor Chart

Visual display of a section of the GO directed acyclic graph (DAG) for a single GO term. Terms in the GO are linked to parent (more general) terms and often to child (more specific) terms by one or more 'relationships'

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.

GO:0008150 biological_process
GO:0065007 biological regulation
GO:0008152 metabolic process
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0043170 macromolecule metabolic process
GO:0048519 negative regulation of biological process
GO:0010467 gene expression
GO:0019222 regulation of metabolic process
GO:0009892 negative regulation of metabolic process
GO:0060255 regulation of macromolecule metabolic process
GO:0010468 regulation of gene expression
GO:0010605 negative regulation of macromolecule metabolic process
GO:0010629 negative regulation of gene expression
GO:0016458 gene silencing

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
I GO:0006342 chromatin silencing
I GO:0016441 posttranscriptional gene silencing
I GO:0031047 gene silencing by RNA
R GO:0060968 regulation of gene silencing
NR GO:0060969 negative regulation of gene silencing
I GO:0010978 gene silencing involved in chronological cell aging

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

This display shows those GO terms which have been annotated to the same proteins as this term.
Terms may have been co-annotated either by electronic (IEA) or manual annotation methods. Users can decide which evidence code type should be used in the calculation of the co-occurence statistics.
Click on the 'Update' button to run the co-occurence calculation
IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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