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GO:0016458 gene silencing

Term Information

ID GO:0016458
Name gene silencing
Ontology Biological Process
Definition Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.
Comment Note that this process is the opposite of long-term maintenance of gene activation.
GONUTS GO:0016458 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related long-term maintenance of gene inactivation

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_pir462

Cross-references

Database ID
Wikipedia Gene_silencing

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016458:
Relationship To GO:0016458 Child Term Child Term Name
Is a GO:0006342 chromatin silencing
Is a GO:0016441 posttranscriptional gene silencing
Is a GO:0031047 gene silencing by RNA
Regulates GO:0060968 regulation of gene silencing
Negatively regulates GO:0060969 negative regulation of gene silencing
Is a GO:0010978 gene silencing involved in chronological cell aging

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
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Date
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016458. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016458 based on the entire annotation set Co-occurrence statistics for GO:0016458 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2012-12-15 Added RELATION is a GO:0044763 (single-organism cellular process)
2012-12-15 Deleted RELATION is a GO:0009987 (cellular process)
2009-03-29 Added XREF Wikipedia:Gene_silencing
2009-02-13 Deleted DEFINITION Any transcriptional or post-transcriptional process carried out at thencellular level that results in long-term gene inactivation.
2009-02-13 Added DEFINITION Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.
2009-02-12 Deleted DEFINITION Any mechanism, at the level of transcription or post-transcription, causing long-term gene inactivation.
2009-02-12 Added DEFINITION Any transcriptional or post-transcriptional process carried out at thencellular level that results in long-term gene inactivation.
2009-02-12 Added RELATION is a GO:0009987 (cellular process)
2008-08-14 Added RELATION is a GO:0010629 (negative regulation of gene expression)
2008-08-14 Deleted RELATION is a GO:0010468 (regulation of gene expression)
2008-06-09 Added SLIM goslim_pir
2008-05-13 Added DEFINITION Any mechanism, at the level of transcription or post-transcription, causing long-term gene inactivation.
2008-05-12 Deleted DEFINITION Any mechanism, at the level of transcription or post-transcription, causing long-term gene inactivation.
2008-04-19 Deleted RELATION is a GO:0006139 (nucleobase-containing compound metabolic process)
2008-04-01 Updated RELATION is a GO:0006139 (nucleobase-containing compound metabolic process)
2008-04-01 Updated RELATION is a GO:0010468 (regulation of gene expression)
2007-08-09 Added SYNONYM long-term maintenance of gene inactivation
2007-08-09 Deleted SYNONYM long-term maintenance of gene inactivation
2004-04-19 Added SYNONYM long-term maintenance of gene inactivation
2004-04-05 Deleted SYNONYM long-term maintenance of gene inactivation
2003-07-01 Added SYNONYM long-term maintenance of gene inactivation
2003-06-18 Added DEFINITION Any mechanism, at the level of transcription or post-transcription, causing long-term gene inactivation.
2002-02-06 Updated TERM gene silencing
2001-04-03 Updated TERM gene silencing
2001-03-30 Added TERM gene silencing

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM gene silencing
2001-04-03 Updated TERM gene silencing
2001-03-30 Added TERM gene silencing

Definition/synonyms

Timestamp Action Category Detail
2009-02-13 Deleted DEFINITION Any transcriptional or post-transcriptional process carried out at thencellular level that results in long-term gene inactivation.
2009-02-13 Added DEFINITION Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.
2009-02-12 Deleted DEFINITION Any mechanism, at the level of transcription or post-transcription, causing long-term gene inactivation.
2009-02-12 Added DEFINITION Any transcriptional or post-transcriptional process carried out at thencellular level that results in long-term gene inactivation.
2008-05-13 Added DEFINITION Any mechanism, at the level of transcription or post-transcription, causing long-term gene inactivation.
2008-05-12 Deleted DEFINITION Any mechanism, at the level of transcription or post-transcription, causing long-term gene inactivation.
2007-08-09 Added SYNONYM long-term maintenance of gene inactivation
2007-08-09 Deleted SYNONYM long-term maintenance of gene inactivation
2004-04-19 Added SYNONYM long-term maintenance of gene inactivation
2004-04-05 Deleted SYNONYM long-term maintenance of gene inactivation
2003-07-01 Added SYNONYM long-term maintenance of gene inactivation
2003-06-18 Added DEFINITION Any mechanism, at the level of transcription or post-transcription, causing long-term gene inactivation.

Relationships

Timestamp Action Category Detail
2012-12-15 Added RELATION is a GO:0044763 (single-organism cellular process)
2012-12-15 Deleted RELATION is a GO:0009987 (cellular process)
2009-02-12 Added RELATION is a GO:0009987 (cellular process)
2008-08-14 Added RELATION is a GO:0010629 (negative regulation of gene expression)
2008-08-14 Deleted RELATION is a GO:0010468 (regulation of gene expression)
2008-04-19 Deleted RELATION is a GO:0006139 (nucleobase-containing compound metabolic process)
2008-04-01 Updated RELATION is a GO:0006139 (nucleobase-containing compound metabolic process)
2008-04-01 Updated RELATION is a GO:0010468 (regulation of gene expression)

Cross-references

Timestamp Action Category Detail
2009-03-29 Added XREF Wikipedia:Gene_silencing

Other

Timestamp Action Category Detail
2013-04-18 Updated SLIM goslim_pir
2008-06-09 Added SLIM goslim_pir
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