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GO:0016286 small conductance calcium-activated potassium channel activity

Catalysis of the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.

Term Information

ID GO:0016286
Name small conductance calcium-activated potassium channel activity
Ontology Molecular Function
Definition Catalysis of the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
Comment

Synonyms

Type Synonym
exact small conductance KCa channels
exact SK calcium-activated potassium channel activity
exact SK KCa channels

Cross-references associated with this term:

Database ID
INTERPRO IPR003931

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Ancestor Table

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GO:0003674 molecular_function
GO:0005215 transporter activity
GO:0022892 substrate-specific transporter activity
GO:0022857 transmembrane transporter activity
GO:0022803 passive transmembrane transporter activity
GO:0022891 substrate-specific transmembrane transporter activity
GO:0015267 channel activity
GO:0015075 ion transmembrane transporter activity
GO:0022836 gated channel activity
GO:0022839 ion gated channel activity
GO:0008324 cation transmembrane transporter activity
GO:0046873 metal ion transmembrane transporter activity
GO:0022838 substrate-specific channel activity
GO:0005216 ion channel activity
GO:0005261 cation channel activity
GO:0005227 calcium activated cation channel activity
GO:0005267 potassium channel activity
GO:0015269 calcium-activated potassium channel activity
GO:0016286 small conductance calcium-activated potassium channel activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
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Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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