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GO:0016082 synaptic vesicle priming

Term Information

ID GO:0016082
Name synaptic vesicle priming
Ontology Biological Process
Definition A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane.
PMID:15217342
Comment Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission. (dos, pvn, fk synapse project 2015)
GONUTS GO:0016082 Wiki Page

GO Discussions

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Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0051640 organelle localization only_in_taxon 2759 Eukaryota
GO:0099536 synaptic signaling never_in_taxon 4895 Schizosaccharomyces
More information on taxon constraints in GO is available here

GO Slims

This term is present in the following GO Consortium-maintained GO slims:
GO slim nameCount of all terms
goslim_synapse301

Cross-references

Database ID
InterPro IPR027082

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016082:
Relationship To GO:0016082 Child Term Child Term Name
Regulates GO:0010807 regulation of synaptic vesicle priming
Positively regulates GO:0010808 positive regulation of synaptic vesicle priming
Negatively regulates GO:0010809 negative regulation of synaptic vesicle priming

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016082. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016082 based on the entire annotation set Co-occurrence statistics for GO:0016082 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2016-01-20 Added DEFINITION A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane.
2016-01-20 Deleted DEFINITION The formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
2016-01-20 Added RELATION is a GO:0099531 (presynaptic process involved in chemical synaptic transmission)
2014-12-13 Added SLIM goslim_synapse
2008-05-13 Added DEFINITION The formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
2008-05-12 Deleted DEFINITION The formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
2008-04-01 Updated RELATION is a GO:0043623 (cellular protein complex assembly)
2008-04-01 Updated RELATION part of GO:0016079 (synaptic vesicle exocytosis)
2006-01-18 Updated DEFINITION The formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
2003-08-01 Added DEFINITION Preparation of the presynaptic membrane with GTP-binding protein to allow assembly of a protein coat that will form the shape of the vesicle and target it to its destination.
2002-02-06 Updated TERM synaptic vesicle priming
2001-04-03 Updated TERM synaptic vesicle priming
2001-03-30 Added TERM synaptic vesicle priming

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM synaptic vesicle priming
2001-04-03 Updated TERM synaptic vesicle priming
2001-03-30 Added TERM synaptic vesicle priming

Definition/synonyms

Timestamp Action Category Detail
2016-01-20 Added DEFINITION A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane.
2016-01-20 Deleted DEFINITION The formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
2008-05-13 Added DEFINITION The formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
2008-05-12 Deleted DEFINITION The formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
2006-01-18 Updated DEFINITION The formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
2003-08-01 Added DEFINITION Preparation of the presynaptic membrane with GTP-binding protein to allow assembly of a protein coat that will form the shape of the vesicle and target it to its destination.

Relationships

Timestamp Action Category Detail
2016-01-20 Added RELATION is a GO:0099531 (presynaptic process involved in chemical synaptic transmission)
2008-04-01 Updated RELATION is a GO:0043623 (cellular protein complex assembly)
2008-04-01 Updated RELATION part of GO:0016079 (synaptic vesicle exocytosis)

Other

Timestamp Action Category Detail
2014-12-13 Added SLIM goslim_synapse
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