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GO:0016068 type I hypersensitivity

An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.

Term Information

ID GO:0016068
Name type I hypersensitivity
Ontology Biological Process
Definition An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.
Comment Note that localized and systemic anaphylaxis is usually a result of type I hypersensitivity.

Synonyms

Type Synonym
exact immediate hypersensitivity response

Cross-references associated with this term:

Database ID
INTERPRO IPR001778
INTERPRO IPR002914
Wikipedia Type_I_hypersensitivity
INTERPRO IPR002411

Web service: term information

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Ancestor Chart

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0008150 biological_process
GO:0002376 immune system process
GO:0050896 response to stimulus
GO:0009605 response to external stimulus
GO:0006950 response to stress
GO:0006952 defense response
GO:0006955 immune response
GO:0002250 adaptive immune response
GO:0009611 response to wounding
GO:0002252 immune effector process
GO:0002443 leukocyte mediated immunity
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
GO:0002449 lymphocyte mediated immunity
GO:0006954 inflammatory response
GO:0002526 acute inflammatory response
GO:0002437 inflammatory response to antigenic stimulus
GO:0019724 B cell mediated immunity
GO:0016064 immunoglobulin mediated immune response
GO:0002438 acute inflammatory response to antigenic stimulus
GO:0002524 hypersensitivity
GO:0016068 type I hypersensitivity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
R GO:0001810 regulation of type I hypersensitivity
NR GO:0001811 negative regulation of type I hypersensitivity
PR GO:0001812 positive regulation of type I hypersensitivity
I GO:0002558 type I hypersensitivity mediated by mast cells
I GO:0002559 type I hypersensitivity mediated by basophils

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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