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GO:0016055 Wnt signaling pathway

Term Information

ID GO:0016055
Name Wnt signaling pathway
Ontology Biological Process
Definition The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
PMID:11532397
Secondary IDs GO:0007222
GONUTS GO:0016055 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact Wnt receptor signalling pathway
exact Wg signaling pathway
exact Wg signalling pathway
exact Wingless signaling pathway
exact frizzled signaling pathway
exact frizzled signalling pathway
related Wnt-activated signaling pathway
exact Wnt receptor signaling pathway
exact Wingless signalling pathway

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO.
If you would like to be involved in discussions regarding this development activity, please email the GO Consortium.
Please note that it is still appropriate to use this term for curation or analysis purposes.
Ontology Development Project
signallingLink

Cross-references

Database ID
InterPro IPR003064
InterPro IPR005817
InterPro IPR008339
InterPro IPR008340
InterPro IPR008341
InterPro IPR008342
InterPro IPR009139
InterPro IPR009140
InterPro IPR009141
InterPro IPR009142
InterPro IPR009143
InterPro IPR009223
InterPro IPR009224
InterPro IPR009232
InterPro IPR009234
InterPro IPR009240
InterPro IPR009551
InterPro IPR013300
InterPro IPR013301
InterPro IPR013302
InterPro IPR013303
InterPro IPR013304
InterPro IPR015506
InterPro IPR017076
InterPro IPR024940
InterPro IPR026542
InterPro IPR026543
InterPro IPR026547
InterPro IPR026548
InterPro IPR026549
InterPro IPR026550
InterPro IPR026551
InterPro IPR026552
InterPro IPR026553
InterPro IPR026554
InterPro IPR027719
InterPro IPR028408
InterPro IPR028731
InterPro IPR028769
InterPro IPR028782
InterPro IPR029094
InterPro IPR029800
InterPro IPR030462
InterPro IPR031187
UniProtKB-KW Wnt signaling pathway

Replaces

This term can be used instead of these obsolete terms:
GO Identifier GO Term Name Reason
GO:0004928 frizzled receptor activity CONSIDER GO:0016055

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016055:
Relationship To GO:0016055 Child Term Child Term Name
Is a GO:0022002 negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway
Regulates GO:0030111 regulation of Wnt signaling pathway
Positively regulates GO:0030177 positive regulation of Wnt signaling pathway
Negatively regulates GO:0030178 negative regulation of Wnt signaling pathway
Is a GO:0003306 Wnt signaling pathway involved in heart development
Is a GO:0060833 Wnt signaling pathway involved in animal/vegetal axis specification
Is a GO:0090011 Wnt signaling pathway involved in primitive streak formation
Is a GO:0035567 non-canonical Wnt signaling pathway
Is a GO:0060593 Wnt signaling pathway involved in mammary gland specification
Is a GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification
Is a GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis
Is a GO:0061289 Wnt signaling pathway involved in kidney development
Part of GO:0071936 coreceptor activity involved in Wnt signaling pathway
Is a GO:0060070 canonical Wnt signaling pathway
Is a GO:0021874 Wnt signaling pathway involved in forebrain neuroblast division
Is a GO:0021922 Wnt signaling pathway involved in regulation of cell proliferation in dorsal spinal cord
Is a GO:0090021 positive regulation of posterior neural plate formation by Wnt signaling pathway
Is a GO:0021881 Wnt-activated signaling pathway involved in forebrain neuron fate commitment
Is a GO:0090244 Wnt signaling pathway involved in somitogenesis
Positively regulates GO:0060804 positive regulation of Wnt signaling pathway by BMP signaling pathway
Regulates GO:0061359 regulation of Wnt signaling pathway by Wnt protein secretion
Negatively regulates GO:0038012 negative regulation of Wnt signaling pathway by Wnt receptor internalization
Positively regulates GO:0038013 positive regulation of Wnt signaling pathway by Wnt receptor internalization
Is a GO:0035659 Wnt signaling pathway involved in wound healing, spreading of epidermal cells

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016055. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016055 based on the entire annotation set Co-occurrence statistics for GO:0016055 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-12-11 Added SYNONYM Wnt receptor signaling pathway
2013-12-11 Added SYNONYM Wnt-activated signaling pathway
2013-12-11 Updated TERM Wnt signaling pathway
2010-07-09 Deleted DEFINITION The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
2010-07-09 Added DEFINITION The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
2010-04-14 Deleted RELATION is a GO:0023034 (intracellular signaling pathway)
2010-02-20 Added RELATION is a GO:0023034 (intracellular signaling pathway)
2010-02-04 Added SYNONYM Wingless signalling pathway
2010-02-04 Added SYNONYM Wg signaling pathway
2010-02-04 Added SYNONYM Wg signalling pathway
2010-02-04 Added SYNONYM Wingless signaling pathway
2008-05-13 Added DEFINITION The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
2008-05-12 Deleted DEFINITION The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
2008-04-01 Updated RELATION is a GO:0007166 (cell surface receptor signaling pathway)
2007-10-08 Deleted SYNONYM Wnt receptor signaling pathway
2007-08-09 Added SYNONYM Wnt receptor signaling pathway
2007-08-09 Added SYNONYM Wnt receptor signalling pathway
2007-08-09 Added SYNONYM frizzled signaling pathway
2007-08-09 Added SYNONYM frizzled signalling pathway
2007-08-09 Deleted SYNONYM Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM frizzled signaling pathway
2007-08-09 Deleted SYNONYM frizzled signalling pathway
2007-08-09 Deleted SYNONYM Wnt receptor signalling pathway
2007-03-20 Updated DEFINITION The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
2007-03-16 Added SECONDARY GO:0007222 (frizzled signaling pathway)
2007-03-16 Added SYNONYM Wnt receptor signaling pathway
2007-03-16 Added SYNONYM frizzled signaling pathway
2007-03-16 Added SYNONYM frizzled signalling pathway
2006-02-25 Deleted SYNONYM wnt receptor signaling pathway
2006-02-25 Deleted SYNONYM wnt receptor signalling pathway
2005-12-15 Added SYNONYM wnt receptor signaling pathway
2005-12-15 Added SYNONYM wnt receptor signalling pathway
2004-07-15 Updated DEFINITION The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell.
2004-04-19 Added SYNONYM Wnt receptor signalling pathway
2004-04-16 Deleted SYNONYM Wnt receptor signalling pathway
2003-11-13 Added SYNONYM Wnt receptor signalling pathway
2003-08-07 Added DEFINITION A pathway of signal transduction initiated by binding of Wnt protein to a receptor on the surface of the target cell.
2002-02-06 Updated TERM Wnt receptor signaling pathway
2001-04-03 Updated TERM Wnt receptor signaling pathway
2001-03-30 Added TERM Wnt receptor signaling pathway

Term

Timestamp Action Category Detail
2013-12-11 Updated TERM Wnt signaling pathway
2002-02-06 Updated TERM Wnt receptor signaling pathway
2001-04-03 Updated TERM Wnt receptor signaling pathway
2001-03-30 Added TERM Wnt receptor signaling pathway

Definition/synonyms

Timestamp Action Category Detail
2013-12-11 Added SYNONYM Wnt receptor signaling pathway
2013-12-11 Added SYNONYM Wnt-activated signaling pathway
2010-07-09 Deleted DEFINITION The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
2010-07-09 Added DEFINITION The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
2010-02-04 Added SYNONYM Wingless signalling pathway
2010-02-04 Added SYNONYM Wg signaling pathway
2010-02-04 Added SYNONYM Wg signalling pathway
2010-02-04 Added SYNONYM Wingless signaling pathway
2008-05-13 Added DEFINITION The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
2008-05-12 Deleted DEFINITION The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
2007-10-08 Deleted SYNONYM Wnt receptor signaling pathway
2007-08-09 Added SYNONYM Wnt receptor signaling pathway
2007-08-09 Added SYNONYM Wnt receptor signalling pathway
2007-08-09 Added SYNONYM frizzled signaling pathway
2007-08-09 Added SYNONYM frizzled signalling pathway
2007-08-09 Deleted SYNONYM Wnt receptor signaling pathway
2007-08-09 Deleted SYNONYM frizzled signaling pathway
2007-08-09 Deleted SYNONYM frizzled signalling pathway
2007-08-09 Deleted SYNONYM Wnt receptor signalling pathway
2007-03-20 Updated DEFINITION The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
2007-03-16 Added SYNONYM Wnt receptor signaling pathway
2007-03-16 Added SYNONYM frizzled signaling pathway
2007-03-16 Added SYNONYM frizzled signalling pathway
2006-02-25 Deleted SYNONYM wnt receptor signaling pathway
2006-02-25 Deleted SYNONYM wnt receptor signalling pathway
2005-12-15 Added SYNONYM wnt receptor signaling pathway
2005-12-15 Added SYNONYM wnt receptor signalling pathway
2004-07-15 Updated DEFINITION The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell.
2004-04-19 Added SYNONYM Wnt receptor signalling pathway
2004-04-16 Deleted SYNONYM Wnt receptor signalling pathway
2003-11-13 Added SYNONYM Wnt receptor signalling pathway
2003-08-07 Added DEFINITION A pathway of signal transduction initiated by binding of Wnt protein to a receptor on the surface of the target cell.

Relationships

Timestamp Action Category Detail
2010-04-14 Deleted RELATION is a GO:0023034 (intracellular signaling pathway)
2010-02-20 Added RELATION is a GO:0023034 (intracellular signaling pathway)
2008-04-01 Updated RELATION is a GO:0007166 (cell surface receptor signaling pathway)

Other

Timestamp Action Category Detail
2007-03-16 Added SECONDARY GO:0007222 (frizzled signaling pathway)
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