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GO:0016011 dystroglycan complex

Term Information

ID GO:0016011
Name dystroglycan complex
Ontology Cellular Component
Definition A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
PMID:15117830 PMID:16710609
GONUTS GO:0016011 Wiki Page

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0016011:
Relationship To GO:0016011 Child Term Child Term Name
Part of GO:0016012 sarcoglycan complex

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0016011. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0016011 based on the entire annotation set Co-occurrence statistics for GO:0016011 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-07-11 Deleted RELATION is a GO:0044444 (cytoplasmic part)
2008-07-11 Deleted RELATION is a GO:0044421 (extracellular region part)
2008-07-11 Deleted RELATION is a GO:0044420 (extracellular matrix part)
2008-07-07 Deleted DEFINITION Includes alpha- and beta-dystroglycan; alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
2008-07-07 Added DEFINITION A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
2008-05-13 Added DEFINITION Includes alpha- and beta-dystroglycan; alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
2008-05-12 Deleted DEFINITION Includes alpha- and beta-dystroglycan; alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
2008-04-01 Updated RELATION is a GO:0044459 (plasma membrane part)
2008-04-01 Updated RELATION is a GO:0044444 (cytoplasmic part)
2008-04-01 Updated RELATION is a GO:0044421 (extracellular region part)
2008-04-01 Updated RELATION is a GO:0044420 (extracellular matrix part)
2008-04-01 Updated RELATION part of GO:0016010 (dystrophin-associated glycoprotein complex)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2006-09-26 Updated DEFINITION Includes alpha- and beta-dystroglycan; alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
2002-02-06 Updated TERM dystroglycan complex
2001-08-06 Added DEFINITION Includes alpha- and beta-dystroglycan; alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
2001-04-03 Updated TERM dystroglycan complex
2001-03-30 Added TERM dystroglycan complex

Term

Timestamp Action Category Detail
2002-02-06 Updated TERM dystroglycan complex
2001-04-03 Updated TERM dystroglycan complex
2001-03-30 Added TERM dystroglycan complex

Definition/synonyms

Timestamp Action Category Detail
2008-07-07 Deleted DEFINITION Includes alpha- and beta-dystroglycan; alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
2008-07-07 Added DEFINITION A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
2008-05-13 Added DEFINITION Includes alpha- and beta-dystroglycan; alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
2008-05-12 Deleted DEFINITION Includes alpha- and beta-dystroglycan; alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
2006-09-26 Updated DEFINITION Includes alpha- and beta-dystroglycan; alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
2001-08-06 Added DEFINITION Includes alpha- and beta-dystroglycan; alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.

Relationships

Timestamp Action Category Detail
2008-07-11 Deleted RELATION is a GO:0044444 (cytoplasmic part)
2008-07-11 Deleted RELATION is a GO:0044421 (extracellular region part)
2008-07-11 Deleted RELATION is a GO:0044420 (extracellular matrix part)
2008-04-01 Updated RELATION is a GO:0044459 (plasma membrane part)
2008-04-01 Updated RELATION is a GO:0044444 (cytoplasmic part)
2008-04-01 Updated RELATION is a GO:0044421 (extracellular region part)
2008-04-01 Updated RELATION is a GO:0044420 (extracellular matrix part)
2008-04-01 Updated RELATION part of GO:0016010 (dystrophin-associated glycoprotein complex)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
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