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GO:0015667 site-specific DNA-methyltransferase (cytosine-N4-specific) activity

Term Information

ID GO:0015667
Name site-specific DNA-methyltransferase (cytosine-N4-specific) activity
Ontology Molecular Function
Definition Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.
GONUTS GO:0015667 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact DNA[cytosine-N4]methyltransferase activity
exact m4C-forming MTase activity
exact S-adenosyl-L-methionine:DNA-cytosine N4-methyltransferase activity
related restriction-modification system activity
exact S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase activity
exact N(4)-cytosine-specific DNA methylase activity
related modification methylase activity
exact N4-cytosine-specific DNA methylase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0006306 DNA methylation never_in_taxon 4895 Schizosaccharomyces
GO:0006306 DNA methylation never_in_taxon 4930 Saccharomyces
More information on taxon constraints in GO is available here

Cross-references

Database ID
EC 2.1.1.113
InterPro IPR017985
MetaCyc 2.1.1.113-RXN

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0015667:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0015667. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0015667 based on the entire annotation set Co-occurrence statistics for GO:0015667 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-07-16 Added RELATION part of GO:0090124 (N-4 methylation of cytosine)
2008-05-13 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.
2008-04-01 Updated RELATION is a GO:0009008 (DNA-methyltransferase activity)
2008-04-01 Updated RELATION is a GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity)
2007-11-08 Added SYNONYM DNA[cytosine-N4]methyltransferase activity
2007-11-08 Added SYNONYM N4-cytosine-specific DNA methylase activity
2007-11-08 Added SYNONYM S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase activity
2007-11-08 Added SYNONYM S-adenosyl-L-methionine:DNA-cytosine N4-methyltransferase activity
2007-11-08 Added SYNONYM m4C-forming MTase activity
2007-09-06 Added SYNONYM N(4)-cytosine-specific DNA methylase activity
2007-09-06 Added SYNONYM modification methylase activity
2007-09-06 Added SYNONYM restriction-modification system activity
2003-10-27 Added XREF MetaCyc:2.1.1.113-RXN
2003-03-19 Updated TERM site-specific DNA-methyltransferase (cytosine-N4-specific) activity
2002-11-27 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.
2002-02-06 Updated TERM site-specific DNA-methyltransferase (cytosine-N4-specific)
2001-04-03 Updated TERM site-specific DNA-methyltransferase (cytosine-N4-specific)
2001-03-30 Added XREF EC:2.1.1.113
2001-03-30 Added TERM site-specific DNA-methyltransferase (cytosine-N4-specific)

Term

Timestamp Action Category Detail
2003-03-19 Updated TERM site-specific DNA-methyltransferase (cytosine-N4-specific) activity
2002-02-06 Updated TERM site-specific DNA-methyltransferase (cytosine-N4-specific)
2001-04-03 Updated TERM site-specific DNA-methyltransferase (cytosine-N4-specific)
2001-03-30 Added TERM site-specific DNA-methyltransferase (cytosine-N4-specific)

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.
2007-11-08 Added SYNONYM DNA[cytosine-N4]methyltransferase activity
2007-11-08 Added SYNONYM N4-cytosine-specific DNA methylase activity
2007-11-08 Added SYNONYM S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase activity
2007-11-08 Added SYNONYM S-adenosyl-L-methionine:DNA-cytosine N4-methyltransferase activity
2007-11-08 Added SYNONYM m4C-forming MTase activity
2007-09-06 Added SYNONYM N(4)-cytosine-specific DNA methylase activity
2007-09-06 Added SYNONYM modification methylase activity
2007-09-06 Added SYNONYM restriction-modification system activity
2002-11-27 Added DEFINITION Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.

Relationships

Timestamp Action Category Detail
2010-07-16 Added RELATION part of GO:0090124 (N-4 methylation of cytosine)
2008-04-01 Updated RELATION is a GO:0009008 (DNA-methyltransferase activity)
2008-04-01 Updated RELATION is a GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:2.1.1.113-RXN
2001-03-30 Added XREF EC:2.1.1.113
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