spacer

GO:0015627 type II protein secretion system complex

Term Information

ID GO:0015627
Name type II protein secretion system complex
Ontology Cellular Component
Definition A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.
PMID:16448494
Comment Note that the type II protein secretion system complex does not include components of the Sec or Tat pathways. For components of these pathways, consider annotating to 'cell envelope Sec complex ; GO:0031522' or 'TAT protein translocation system complex ; GO:0033281'.
GONUTS GO:0015627 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact main terminal branch
exact T2SS-associated complexes
related general secretion pathway-associated complex
related Sec-dependent secretion system-associated complex
exact MTB

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR000645
InterPro IPR000983
InterPro IPR001639
InterPro IPR002416
InterPro IPR003413
InterPro IPR010052
InterPro IPR010054
InterPro IPR010055
InterPro IPR011850
InterPro IPR013356
InterPro IPR013369
InterPro IPR022346

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0015627:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0015627. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0015627 based on the entire annotation set Co-occurrence statistics for GO:0015627 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-06-18 Added RELATION capable of part of GO:0015628 (protein secretion by the type II secretion system)
2008-10-02 Added DEFINITION A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.
2008-10-02 Deleted DEFINITION A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of secreted proteins from the cytoplasm into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane.
2008-10-02 Deleted SYNONYM type II protein (Sec) secretion system complex
2008-05-13 Added DEFINITION A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of secreted proteins from the cytoplasm into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane.
2008-05-12 Deleted DEFINITION A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of secreted proteins from the cytoplasm into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane.
2008-04-01 Updated RELATION is a GO:0044464 (cell part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
2007-08-09 Added SYNONYM MTB
2007-08-09 Added SYNONYM Sec-dependent secretion system-associated complex
2007-08-09 Added SYNONYM T2SS-associated complexes
2007-08-09 Added SYNONYM general secretion pathway-associated complex
2007-08-09 Added SYNONYM main terminal branch
2007-08-09 Added SYNONYM type II protein (Sec) secretion system complex
2007-08-09 Deleted SYNONYM MTB
2007-08-09 Deleted SYNONYM Sec-dependent secretion system-associated complex
2007-08-09 Deleted SYNONYM T2SS-associated complexes
2007-08-09 Deleted SYNONYM general secretion pathway-associated complex
2007-08-09 Deleted SYNONYM main terminal branch
2007-08-09 Deleted SYNONYM type II protein (Sec) secretion system complex
2007-06-27 Added DEFINITION A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of secreted proteins from the cytoplasm into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane.
2007-06-22 Added SYNONYM MTB
2007-06-22 Added SYNONYM Sec-dependent secretion system-associated complex
2007-06-22 Added SYNONYM T2SS-associated complexes
2007-06-22 Added SYNONYM general secretion pathway-associated complex
2007-06-22 Added SYNONYM main terminal branch
2004-04-19 Added SYNONYM type II protein (Sec) secretion system complex
2004-04-16 Deleted SYNONYM type II protein (Sec) secretion system complex
2003-03-01 Added SYNONYM type II protein (Sec) secretion system complex
2003-03-01 Updated TERM type II protein secretion system complex
2002-02-06 Updated TERM type II protein (Sec) secretion system complex
2001-10-01 Updated TERM type II protein (Sec) secretion system complex
2001-04-03 Updated TERM Type II protein (Sec) secretion system complex
2001-03-30 Added TERM Type II protein (Sec) secretion system complex

Term

Timestamp Action Category Detail
2003-03-01 Updated TERM type II protein secretion system complex
2002-02-06 Updated TERM type II protein (Sec) secretion system complex
2001-10-01 Updated TERM type II protein (Sec) secretion system complex
2001-04-03 Updated TERM Type II protein (Sec) secretion system complex
2001-03-30 Added TERM Type II protein (Sec) secretion system complex

Definition/synonyms

Timestamp Action Category Detail
2008-10-02 Added DEFINITION A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.
2008-10-02 Deleted DEFINITION A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of secreted proteins from the cytoplasm into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane.
2008-10-02 Deleted SYNONYM type II protein (Sec) secretion system complex
2008-05-13 Added DEFINITION A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of secreted proteins from the cytoplasm into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane.
2008-05-12 Deleted DEFINITION A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of secreted proteins from the cytoplasm into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane.
2007-08-09 Added SYNONYM MTB
2007-08-09 Added SYNONYM Sec-dependent secretion system-associated complex
2007-08-09 Added SYNONYM T2SS-associated complexes
2007-08-09 Added SYNONYM general secretion pathway-associated complex
2007-08-09 Added SYNONYM main terminal branch
2007-08-09 Added SYNONYM type II protein (Sec) secretion system complex
2007-08-09 Deleted SYNONYM MTB
2007-08-09 Deleted SYNONYM Sec-dependent secretion system-associated complex
2007-08-09 Deleted SYNONYM T2SS-associated complexes
2007-08-09 Deleted SYNONYM general secretion pathway-associated complex
2007-08-09 Deleted SYNONYM main terminal branch
2007-08-09 Deleted SYNONYM type II protein (Sec) secretion system complex
2007-06-27 Added DEFINITION A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of secreted proteins from the cytoplasm into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane.
2007-06-22 Added SYNONYM MTB
2007-06-22 Added SYNONYM Sec-dependent secretion system-associated complex
2007-06-22 Added SYNONYM T2SS-associated complexes
2007-06-22 Added SYNONYM general secretion pathway-associated complex
2007-06-22 Added SYNONYM main terminal branch
2004-04-19 Added SYNONYM type II protein (Sec) secretion system complex
2004-04-16 Deleted SYNONYM type II protein (Sec) secretion system complex
2003-03-01 Added SYNONYM type II protein (Sec) secretion system complex

Relationships

Timestamp Action Category Detail
2015-06-18 Added RELATION capable of part of GO:0015628 (protein secretion by the type II secretion system)
2008-04-01 Updated RELATION is a GO:0044464 (cell part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
15ms