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GO:0015289 obsolete pore-forming toxin activity

This term is obsolete.
This term was made obsolete because it represents a class of gene products.

Term Information

ID GO:0015289
Name obsolete pore-forming toxin activity
Ontology Molecular Function
Definition OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell.
PMID:10839820
Comment This term was made obsolete because it represents a class of gene products.
GONUTS GO:0015289 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact pore-forming toxin activity

Replaced by

This term is obsolete - try one of these terms:
Advice GO Identifier Ontology GO Term Name
Consider GO:0005198 Molecular Function structural molecule activity
Consider GO:0009405 Biological Process pathogenesis
Consider GO:0046930 Cellular Component pore complex
Consider GO:0046931 Biological Process pore complex assembly
Consider GO:0050827 Molecular Function toxin receptor binding

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0015289:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0015289. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0015289 based on the entire annotation set Co-occurrence statistics for GO:0015289 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2015-06-18 Updated TERM obsolete pore-forming toxin activity
2015-06-18 Added SYNONYM pore-forming toxin activity
2010-06-08 Updated TERM pore-forming toxin activity
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2008-06-03 Added OBSOLETION consider GO:0005198 (structural molecule activity)
2008-06-03 Added OBSOLETION consider GO:0009405 (pathogenesis)
2008-06-03 Added OBSOLETION consider GO:0046930 (pore complex)
2008-06-03 Added OBSOLETION consider GO:0046931 (pore complex assembly)
2008-06-03 Added OBSOLETION consider GO:0050827 (toxin receptor binding)
2008-05-13 Added DEFINITION OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell.
2008-05-12 Deleted DEFINITION OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell.
2008-04-01 Updated RELATION is a GO:0008369 (obsolete molecular function)
2003-11-03 Deleted XREF TC:1.C.-.-.-
2003-05-08 Updated DEFINITION OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell.
2003-03-19 Updated TERM pore-forming toxin activity
2002-11-27 Updated DEFINITION Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell.
2002-02-06 Updated TERM pore-forming toxin
2001-08-06 Added DEFINITION A protein or peptide synthesised by one cell and secreted for insertion into the membrane of another cell, where it forms a transmembrane pore. Exerts its toxic effect by allowing the free flow of electrolytes and other small molecules across the membrane.
2001-04-03 Updated TERM pore-forming toxin
2001-03-30 Added XREF TC:1.C.-.-.-
2001-03-30 Added TERM pore-forming toxin

Term

Timestamp Action Category Detail
2015-06-18 Updated TERM obsolete pore-forming toxin activity
2010-06-08 Updated TERM pore-forming toxin activity
2003-03-19 Updated TERM pore-forming toxin activity
2002-02-06 Updated TERM pore-forming toxin
2001-04-03 Updated TERM pore-forming toxin
2001-03-30 Added TERM pore-forming toxin

Obsoletions

Timestamp Action Category Detail
2008-06-03 Added OBSOLETION consider GO:0005198 (structural molecule activity)
2008-06-03 Added OBSOLETION consider GO:0009405 (pathogenesis)
2008-06-03 Added OBSOLETION consider GO:0046930 (pore complex)
2008-06-03 Added OBSOLETION consider GO:0046931 (pore complex assembly)
2008-06-03 Added OBSOLETION consider GO:0050827 (toxin receptor binding)

Definition/synonyms

Timestamp Action Category Detail
2015-06-18 Added SYNONYM pore-forming toxin activity
2008-05-13 Added DEFINITION OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell.
2008-05-12 Deleted DEFINITION OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell.
2003-05-08 Updated DEFINITION OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell.
2002-11-27 Updated DEFINITION Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell.
2001-08-06 Added DEFINITION A protein or peptide synthesised by one cell and secreted for insertion into the membrane of another cell, where it forms a transmembrane pore. Exerts its toxic effect by allowing the free flow of electrolytes and other small molecules across the membrane.

Relationships

Timestamp Action Category Detail
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2008-04-01 Updated RELATION is a GO:0008369 (obsolete molecular function)

Cross-references

Timestamp Action Category Detail
2003-11-03 Deleted XREF TC:1.C.-.-.-
2001-03-30 Added XREF TC:1.C.-.-.-
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