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GO:0015030 Cajal body

A class of nuclear body, first seen after silver staining by Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.

Term Information

ID GO:0015030
Name Cajal body
Ontology Cellular Component
Definition A class of nuclear body, first seen after silver staining by Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
Comment

Synonyms

Type Synonym
exact Gems
exact coiled body

Cross-references associated with this term:

Database ID
Wikipedia Cajal_body

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Ancestor Table

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GO:0005575 cellular_component
GO:0005623 cell
GO:0031974 membrane-enclosed lumen
GO:0043226 organelle
GO:0043227 membrane-bounded organelle
GO:0044464 cell part
GO:0044422 organelle part
GO:0005622 intracellular
GO:0043233 organelle lumen
GO:0044424 intracellular part
GO:0043229 intracellular organelle
GO:0043231 intracellular membrane-bounded organelle
GO:0044446 intracellular organelle part
GO:0005634 nucleus
GO:0070013 intracellular organelle lumen
GO:0044428 nuclear part
GO:0031981 nuclear lumen
GO:0005654 nucleoplasm
GO:0044451 nucleoplasm part
GO:0016604 nuclear body
GO:0015030 Cajal body

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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13ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-11-23-04-03-36
Terminal
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