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GO:0014896 muscle hypertrophy

The enlargement or overgrowth of all or part of an organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.

Term Information

ID GO:0014896
Name muscle hypertrophy
Ontology Biological Process
Definition The enlargement or overgrowth of all or part of an organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.
Comment

Cross-references associated with this term:

Database ID
Wikipedia Muscle_hypertrophy

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Ancestor Chart

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Chart

Ancestor Table

Alternative display of a section of the GO, providing a concise view of the relationships connecting GO terms

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GO:0008150 biological_process
GO:0032501 multicellular organismal process
GO:0003008 system process
GO:0003012 muscle system process
GO:0014896 muscle hypertrophy

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
NR GO:0014741 negative regulation of muscle hypertrophy
PR GO:0014742 positive regulation of muscle hypertrophy
R GO:0014743 regulation of muscle hypertrophy
I GO:0003298 physiological muscle hypertrophy
I GO:0003299 muscle hypertrophy in response to stress
I GO:0014895 smooth muscle hypertrophy
I GO:0014897 striated muscle hypertrophy

Relationship key

CodeRelationship
Ppart of
Iis a

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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11ms
Stand-alone
Hostnametomcat-7.ebi.ac.uk
Uptime16:38 12/10/2009
Data version2009-12-09-04-12-51
Terminal
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