spacer

GO:0014069 postsynaptic density

Term Information

ID GO:0014069
Name postsynaptic density
Ontology Cellular Component
Definition The postsynaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases. The postsynaptic density may be part of a neuron or a muscle cell or a glial cell.
PMID:14532281
GONUTS GO:0014069 Wiki Page
Acknowledgements This term was created by the GO Consortium with support from BHF logo

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact post synaptic density
exact post-synaptic density

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000362 GO:0044456 synapse part only_in_taxon 33208 Metazoa
GOTAX:0000365 GO:0045202 synapse only_in_taxon 33208 Metazoa
More information on taxon constraints in GO is available here

Cross-references

Database ID
NIF_Subcellular sao1196688972
UniProtKB-SubCell Postsynaptic density
Wikipedia Postsynaptic_density

Ancestor Chart

This chart is interactive; you can click on the term boxes and legend for more information.
Display options
Display
Key
GO IDs
Term box width
Term box height
Slim colours
Show children
Image size limit (in megapixels)
Note that setting the limit too high may result in images being generated slowly; it may even cause the browser to crash. The maximum limit is 20 megapixels.

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0014069:
Relationship To GO:0014069 Child Term Child Term Name
Is a GO:0097481 neuronal postsynaptic density
Is a GO:0097482 muscle cell postsynaptic density
Is a GO:0097483 glial cell postsynaptic density

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
Database
Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

Export

Display options

ID Mapping

QuickGO maps between different identifier types by using a combination of mapping files provided by the databases, and using identifier cross-references supplied by UniProtKB.

If more than one identifier type needs to be used to map all required sequences, drag the selected databases to change the order in which identifiers are found.

Filter

Select

Grouped by
Annotation count
Protein count
Both

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0014069. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0014069 based on the entire annotation set Co-occurrence statistics for GO:0014069 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-09-07 Deleted RELATION is a GO:0044463 (cell projection part)
2013-07-04 Deleted DEFINITION The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.
2013-07-04 Added DEFINITION The postsynaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases. The postsynaptic density may be part of a neuron or a muscle cell or a glial cell.
2013-07-04 Deleted RELATION is a GO:0097458 (neuron part)
2013-07-04 Deleted RELATION part of GO:0044327 (dendritic spine head)
2013-06-27 Added RELATION is a GO:0097458 (neuron part)
2012-10-29 Added RELATION is a GO:0044463 (cell projection part)
2011-08-02 Added RELATION part of GO:0044327 (dendritic spine head)
2010-02-04 Added XREF NIF_Subcellular:sao1196688972
2009-11-12 Added SYNONYM post-synaptic density
2009-11-12 Added SYNONYM post synaptic density
2009-02-08 Added XREF Wikipedia:Postsynaptic_density
2008-05-13 Added DEFINITION The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.
2008-05-12 Deleted DEFINITION The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.
2008-04-01 Updated RELATION is a GO:0044456 (synapse part)
2008-04-01 Updated RELATION is a GO:0044430 (cytoskeletal part)
2006-04-22 Added DEFINITION The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.
2006-04-22 Added TERM postsynaptic density

Term

Timestamp Action Category Detail
2006-04-22 Added TERM postsynaptic density

Definition/synonyms

Timestamp Action Category Detail
2013-07-04 Deleted DEFINITION The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.
2013-07-04 Added DEFINITION The postsynaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases. The postsynaptic density may be part of a neuron or a muscle cell or a glial cell.
2009-11-12 Added SYNONYM post-synaptic density
2009-11-12 Added SYNONYM post synaptic density
2008-05-13 Added DEFINITION The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.
2008-05-12 Deleted DEFINITION The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.
2006-04-22 Added DEFINITION The post synaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases.

Relationships

Timestamp Action Category Detail
2013-09-07 Deleted RELATION is a GO:0044463 (cell projection part)
2013-07-04 Deleted RELATION is a GO:0097458 (neuron part)
2013-07-04 Deleted RELATION part of GO:0044327 (dendritic spine head)
2013-06-27 Added RELATION is a GO:0097458 (neuron part)
2012-10-29 Added RELATION is a GO:0044463 (cell projection part)
2011-08-02 Added RELATION part of GO:0044327 (dendritic spine head)
2008-04-01 Updated RELATION is a GO:0044456 (synapse part)
2008-04-01 Updated RELATION is a GO:0044430 (cytoskeletal part)

Cross-references

Timestamp Action Category Detail
2010-02-04 Added XREF NIF_Subcellular:sao1196688972
2009-02-08 Added XREF Wikipedia:Postsynaptic_density
spacer
Please send comments, suggestions or bug reports to goa@ebi.ac.uk. Click here for details of how to cite UniProt-GOA and QuickGO.
13ms