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GO:0010466 negative regulation of peptidase activity

Term Information

ID GO:0010466
Name negative regulation of peptidase activity
Ontology Biological Process
Definition Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.
GONUTS GO:0010466 Wiki Page

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
InterPro IPR008296
InterPro IPR029860
InterPro IPR029864
UniProtKB-KW Bait region
UniProtKB-KW Protease inhibitor

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0010466:
Relationship To GO:0010466 Child Term Child Term Name
Part of GO:0030414 peptidase inhibitor activity
Is a GO:0010951 negative regulation of endopeptidase activity
Is a GO:2000157 negative regulation of ubiquitin-specific protease activity
Is a GO:1902572 negative regulation of serine-type peptidase activity
Is a GO:0035940 negative regulation of peptidase activity in other organism

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0010466. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0010466 based on the entire annotation set Co-occurrence statistics for GO:0010466 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2014-10-18 Added RELATION is a GO:0045861 (negative regulation of proteolysis)
2010-06-15 Added RELATION negatively regulates GO:0008233 (peptidase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0008233 (peptidase activity)
2010-06-09 Updated TERM negative regulation of peptidase activity
2010-06-08 Added RELATION negatively regulates GO:0008233 (peptidase activity)
2010-06-08 Updated TERM negative regulation of peptidase activity
2009-02-25 Updated TERM negative regulation of peptidase activity
2009-02-25 Deleted RELATION negatively regulates GO:0008233 (peptidase activity)
2009-02-22 Added RELATION negatively regulates GO:0008233 (peptidase activity)
2009-02-22 Updated TERM negative regulation of peptidase activity
2008-08-18 Deleted DEFINITION Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide linkages within proteins.
2008-08-18 Added DEFINITION Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.
2008-05-13 Added DEFINITION Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide linkages within proteins.
2008-05-12 Deleted DEFINITION Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide linkages within proteins.
2008-04-01 Updated RELATION is a GO:0051346 (negative regulation of hydrolase activity)
2008-04-01 Updated RELATION is a GO:0052547 (regulation of peptidase activity)
2007-11-27 Added DEFINITION Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide linkages within proteins.
2007-11-17 Added TERM negative regulation of peptidase activity

Term

Timestamp Action Category Detail
2010-06-09 Updated TERM negative regulation of peptidase activity
2010-06-08 Updated TERM negative regulation of peptidase activity
2009-02-25 Updated TERM negative regulation of peptidase activity
2009-02-22 Updated TERM negative regulation of peptidase activity
2007-11-17 Added TERM negative regulation of peptidase activity

Definition/synonyms

Timestamp Action Category Detail
2008-08-18 Deleted DEFINITION Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide linkages within proteins.
2008-08-18 Added DEFINITION Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.
2008-05-13 Added DEFINITION Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide linkages within proteins.
2008-05-12 Deleted DEFINITION Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide linkages within proteins.
2007-11-27 Added DEFINITION Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide linkages within proteins.

Relationships

Timestamp Action Category Detail
2014-10-18 Added RELATION is a GO:0045861 (negative regulation of proteolysis)
2010-06-15 Added RELATION negatively regulates GO:0008233 (peptidase activity)
2010-06-14 Deleted RELATION negatively regulates GO:0008233 (peptidase activity)
2010-06-08 Added RELATION negatively regulates GO:0008233 (peptidase activity)
2009-02-25 Deleted RELATION negatively regulates GO:0008233 (peptidase activity)
2009-02-22 Added RELATION negatively regulates GO:0008233 (peptidase activity)
2008-04-01 Updated RELATION is a GO:0051346 (negative regulation of hydrolase activity)
2008-04-01 Updated RELATION is a GO:0052547 (regulation of peptidase activity)
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