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GO:0009982 pseudouridine synthase activity

Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.

Term Information

ID GO:0009982
Name pseudouridine synthase activity
Ontology Molecular Function
Definition Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
Comment Note that this term should not be confused with 'pseudouridylate synthase activity ; GO:0004730', which refers to the formation of free pseudouridine from uracil and ribose-5-phosphate.

Synonyms

Type Synonym
narrow tRNA-pseudouridine synthase I activity
narrow tRNA pseudouridylate synthase I activity
narrow tRNA-uridine uracilmutase activity
narrow transfer RNA pseudouridine synthetase activity
narrow tRNA-pseudouridine synthase activity
narrow transfer ribonucleate pseudouridine synthetase activity
narrow tRNA-uridine isomerase activity

Cross-references associated with this term:

Database ID
INTERPRO IPR006145
INTERPRO IPR001406
INTERPRO IPR001656
INTERPRO IPR014780
INTERPRO IPR015225
INTERPRO IPR015240
INTERPRO IPR017091
INTERPRO IPR020119
INTERPRO IPR020103
INTERPRO IPR020095
INTERPRO IPR020097
INTERPRO IPR020094
INTERPRO IPR006225
INTERPRO IPR006224
INTERPRO IPR011760
MetaCyc TRNA-PSEUDOURIDINE-SYNTHASE-I-RXN
EC 5.4.99.12

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GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016853 isomerase activity
GO:0016866 intramolecular transferase activity
GO:0009982 pseudouridine synthase activity

Relationship key

Code Relationship
part of
is a
regulates
+ve regulates
-ve regulates

Child Terms

All direct descendants (child terms) available for this GO term:
Term has no children

Protein Annotation

DB
ID
Qualifier colocalizes_with contributes_to NOT NOT|colocalizes_with NOT|contributes_to
GO Term
Reference
Evidence IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP
With
Taxonomy
From
Download limit
Format

Co-occurring Terms

Co-occurrence statistics

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IMP IGI IPI IGC ISS IDA IEP IEA TAS NAS ND IC RCA ISA EXP Statistics may take up to 1 minute to calculate
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