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GO:0009360 DNA polymerase III complex

Term Information

ID GO:0009360
Name DNA polymerase III complex
Ontology Cellular Component
Definition The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork.
PMID:11525729 PMID:12940977
GONUTS GO:0009360 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact DNA polymerase III holoenzyme complex

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
More information on taxon constraints in GO is available here

Cross-references

Database ID
InterPro IPR001001
InterPro IPR010372
InterPro IPR012763
InterPro IPR015199
InterPro IPR022634
InterPro IPR022635
InterPro IPR022637

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0009360:
Relationship To GO:0009360 Child Term Child Term Name
Part of GO:0043846 DNA polymerase III, clamp loader complex
Part of GO:0044775 DNA polymerase III, beta sliding clamp processivity factor complex
Part of GO:0044776 DNA polymerase III, core complex

Protein Annotation

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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0009360. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0009360 based on the entire annotation set Co-occurrence statistics for GO:0009360 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-03-16 Added RELATION has part GO:0043600 (cytoplasmic replisome)
2013-03-15 Added DEFINITION The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork.
2013-03-15 Deleted DEFINITION A DNA polymerase complex that contains two complexes of the catalytic alpha, beta, delta and epsilon polymerase/exonuclease subunits, plus the DnaX complex, a heptamer that includes the tau and gamma products of the dnaX gene and confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.
2013-03-15 Added SYNONYM DNA polymerase III holoenzyme complex
2008-05-13 Added DEFINITION A DNA polymerase complex that contains two complexes of the catalytic alpha, beta, delta and epsilon polymerase/exonuclease subunits, plus the DnaX complex, a heptamer that includes the tau and gamma products of the dnaX gene and confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.
2008-05-12 Deleted DEFINITION A DNA polymerase complex that contains two complexes of the catalytic alpha, beta, delta and epsilon polymerase/exonuclease subunits, plus the DnaX complex, a heptamer that includes the tau and gamma products of the dnaX gene and confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.
2008-04-01 Updated RELATION is a GO:0042575 (DNA polymerase complex)
2007-05-27 Added DEFINITION A DNA polymerase complex that contains two complexes of the catalytic alpha, beta, delta and epsilon polymerase/exonuclease subunits, plus the DnaX complex, a heptamer that includes the tau and gamma products of the dnaX gene and confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.
2002-05-24 Updated TERM DNA polymerase III complex
2002-02-06 Updated TERM DNA polymerase III
2001-04-03 Updated TERM DNA polymerase III
2001-03-30 Added TERM DNA polymerase III

Term

Timestamp Action Category Detail
2002-05-24 Updated TERM DNA polymerase III complex
2002-02-06 Updated TERM DNA polymerase III
2001-04-03 Updated TERM DNA polymerase III
2001-03-30 Added TERM DNA polymerase III

Definition/synonyms

Timestamp Action Category Detail
2013-03-15 Added DEFINITION The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork.
2013-03-15 Deleted DEFINITION A DNA polymerase complex that contains two complexes of the catalytic alpha, beta, delta and epsilon polymerase/exonuclease subunits, plus the DnaX complex, a heptamer that includes the tau and gamma products of the dnaX gene and confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.
2013-03-15 Added SYNONYM DNA polymerase III holoenzyme complex
2008-05-13 Added DEFINITION A DNA polymerase complex that contains two complexes of the catalytic alpha, beta, delta and epsilon polymerase/exonuclease subunits, plus the DnaX complex, a heptamer that includes the tau and gamma products of the dnaX gene and confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.
2008-05-12 Deleted DEFINITION A DNA polymerase complex that contains two complexes of the catalytic alpha, beta, delta and epsilon polymerase/exonuclease subunits, plus the DnaX complex, a heptamer that includes the tau and gamma products of the dnaX gene and confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.
2007-05-27 Added DEFINITION A DNA polymerase complex that contains two complexes of the catalytic alpha, beta, delta and epsilon polymerase/exonuclease subunits, plus the DnaX complex, a heptamer that includes the tau and gamma products of the dnaX gene and confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.

Relationships

Timestamp Action Category Detail
2013-03-16 Added RELATION has part GO:0043600 (cytoplasmic replisome)
2008-04-01 Updated RELATION is a GO:0042575 (DNA polymerase complex)
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