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GO:0009353 mitochondrial oxoglutarate dehydrogenase complex

Term Information

ID GO:0009353
Name mitochondrial oxoglutarate dehydrogenase complex
Ontology Cellular Component
Definition A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. An example of this complex is found in Mus musculus.
PMID:10848975
Comment See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.
GONUTS GO:0009353 Wiki Page

Taxon Constraints

The use of this term should conform to the following taxon constraints:
Taxon Rule Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GOTAX:0000057 GO:0005623 cell only_in_taxon 131567 cellular organisms
GOTAX:0000060 GO:0005739 mitochondrion only_in_taxon 2759 Eukaryota
GOTAX:0000068 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex only_in_taxon 2759 Eukaryota
More information on taxon constraints in GO is available here

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0009353:
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Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0009353. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0009353 based on the entire annotation set Co-occurrence statistics for GO:0009353 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2013-08-15 Added RELATION is a GO:0005947 (mitochondrial alpha-ketoglutarate dehydrogenase complex)
2013-08-15 Deleted RELATION is a GO:0044429 (mitochondrial part)
2013-02-02 Deleted RELATION part of GO:0005739 (mitochondrion)
2012-10-29 Added RELATION part of GO:0005739 (mitochondrion)
2009-08-06 Deleted SYNONYM oxoglutarate dehydrogenase complex (sensu Eukaryota)
2009-08-06 Added DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. An example of this complex is found in Mus musculus.
2009-08-06 Deleted DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix.
2008-05-13 Added DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix.
2008-05-12 Deleted DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix.
2008-04-01 Updated RELATION is a GO:0045252 (oxoglutarate dehydrogenase complex)
2008-04-01 Updated RELATION part of GO:0005759 (mitochondrial matrix)
2008-04-01 Updated RELATION is a GO:0044429 (mitochondrial part)
2007-08-09 Added SYNONYM oxoglutarate dehydrogenase complex (sensu Eukaryota)
2007-08-09 Deleted SYNONYM oxoglutarate dehydrogenase complex (sensu Eukaryota)
2007-02-16 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix.
2007-02-12 Added SYNONYM oxoglutarate dehydrogenase complex (sensu Eukaryota)
2007-02-12 Updated TERM mitochondrial oxoglutarate dehydrogenase complex
2007-01-18 Updated TERM oxoglutarate dehydrogenase complex (sensu Eukaryota)
2007-01-15 Updated TERM oxoglutarate dehydrogenase complex (sensu the Eukaryota research community)
2004-09-19 Updated TERM oxoglutarate dehydrogenase complex (sensu Eukaryota)
2004-07-22 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. As in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2004-07-09 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix (GO:0005759). As in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2003-10-23 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix (GO:0005759). Found in eukaryotes.
2002-11-27 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide within the mitochondrial matrix (GO:0005759). Found in eukaryotes.
2002-05-10 Updated TERM oxoglutarate dehydrogenase complex (sensu Eukarya)
2002-02-06 Updated TERM oxoglutarate dehydrogenase complex
2001-08-06 Added DEFINITION A complex of multiple copies of three eznymic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyses the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2 within the mitochondrial matrix (GO:0005759).
2001-04-03 Updated TERM oxoglutarate dehydrogenase complex
2001-03-30 Added TERM oxoglutarate dehydrogenase complex

Term

Timestamp Action Category Detail
2007-02-12 Updated TERM mitochondrial oxoglutarate dehydrogenase complex
2007-01-18 Updated TERM oxoglutarate dehydrogenase complex (sensu Eukaryota)
2007-01-15 Updated TERM oxoglutarate dehydrogenase complex (sensu the Eukaryota research community)
2004-09-19 Updated TERM oxoglutarate dehydrogenase complex (sensu Eukaryota)
2002-05-10 Updated TERM oxoglutarate dehydrogenase complex (sensu Eukarya)
2002-02-06 Updated TERM oxoglutarate dehydrogenase complex
2001-04-03 Updated TERM oxoglutarate dehydrogenase complex
2001-03-30 Added TERM oxoglutarate dehydrogenase complex

Definition/synonyms

Timestamp Action Category Detail
2009-08-06 Deleted SYNONYM oxoglutarate dehydrogenase complex (sensu Eukaryota)
2009-08-06 Added DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. An example of this complex is found in Mus musculus.
2009-08-06 Deleted DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix.
2008-05-13 Added DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix.
2008-05-12 Deleted DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix.
2007-08-09 Added SYNONYM oxoglutarate dehydrogenase complex (sensu Eukaryota)
2007-08-09 Deleted SYNONYM oxoglutarate dehydrogenase complex (sensu Eukaryota)
2007-02-16 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix.
2007-02-12 Added SYNONYM oxoglutarate dehydrogenase complex (sensu Eukaryota)
2004-07-22 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. As in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2004-07-09 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix (GO:0005759). As in, but not restricted to, the eukaryotes (Eukaryota, ncbi_taxonomy_id:2759).
2003-10-23 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix (GO:0005759). Found in eukaryotes.
2002-11-27 Updated DEFINITION A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide within the mitochondrial matrix (GO:0005759). Found in eukaryotes.
2001-08-06 Added DEFINITION A complex of multiple copies of three eznymic components: oxoglutarate dehydrogenase (lipoamide) ; GO:0004591 ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; GO:0004149 ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; GO:0004148 ; EC:1.8.1.4 (E3); catalyses the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2 within the mitochondrial matrix (GO:0005759).

Relationships

Timestamp Action Category Detail
2013-08-15 Added RELATION is a GO:0005947 (mitochondrial alpha-ketoglutarate dehydrogenase complex)
2013-08-15 Deleted RELATION is a GO:0044429 (mitochondrial part)
2013-02-02 Deleted RELATION part of GO:0005739 (mitochondrion)
2012-10-29 Added RELATION part of GO:0005739 (mitochondrion)
2008-04-01 Updated RELATION is a GO:0045252 (oxoglutarate dehydrogenase complex)
2008-04-01 Updated RELATION part of GO:0005759 (mitochondrial matrix)
2008-04-01 Updated RELATION is a GO:0044429 (mitochondrial part)
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