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GO:0009036 Type II site-specific deoxyribonuclease activity

Term Information

ID GO:0009036
Name Type II site-specific deoxyribonuclease activity
Ontology Molecular Function
Definition Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.
PMID:12654995
GONUTS GO:0009036 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact Type II restriction enzyme activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.1.21.4
InterPro IPR004221
InterPro IPR004233
InterPro IPR004234
InterPro IPR007636
InterPro IPR007637
InterPro IPR009528
InterPro IPR011336
InterPro IPR011338
InterPro IPR011544
InterPro IPR015109
InterPro IPR015277
InterPro IPR015291
InterPro IPR015307
InterPro IPR015334
InterPro IPR018131
InterPro IPR019044
InterPro IPR019045
InterPro IPR019046
InterPro IPR019057
InterPro IPR019064
InterPro IPR019067
InterPro IPR019068
InterPro IPR019070
InterPro IPR019071
InterPro IPR019072
InterPro IPR019073
InterPro IPR021191
MetaCyc 3.1.21.4-RXN

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0009036:
Relationship To GO:0009036 Child Term Child Term Name
Negatively regulates GO:0032081 negative regulation of Type II site-specific deoxyribonuclease activity
Regulates GO:0032085 regulation of Type II site-specific deoxyribonuclease activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Gene Product ID
Symbol
Qualifier
GO Identifier
GO Term Name
Aspect
Original GO ID
Original GO Term Name
Evidence
Reference
With
Taxon
Date
Assigned By
Product Form ID
Name
Synonym
Type
Taxon Name
Sequence

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0009036. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0009036 based on the entire annotation set Co-occurrence statistics for GO:0009036 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.
2008-05-12 Deleted DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.
2008-04-01 Updated RELATION is a GO:0016888 (endodeoxyribonuclease activity, producing 5'-phosphomonoesters)
2008-04-01 Updated RELATION is a GO:0015666 (restriction endodeoxyribonuclease activity)
2007-08-09 Added SYNONYM Type II restriction enzyme activity
2007-08-09 Deleted SYNONYM Type II restriction enzyme activity
2006-06-08 Added SYNONYM Type II restriction enzyme activity
2006-06-08 Updated TERM Type II site-specific deoxyribonuclease activity
2006-06-06 Updated DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.
2003-10-27 Added XREF MetaCyc:3.1.21.4-RXN
2003-03-19 Updated TERM type II site-specific deoxyribonuclease activity
2002-11-27 Added DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
2002-02-06 Updated TERM type II site-specific deoxyribonuclease
2001-04-03 Updated TERM type II site-specific deoxyribonuclease
2001-03-30 Added XREF EC:3.1.21.4
2001-03-30 Added TERM type II site-specific deoxyribonuclease

Term

Timestamp Action Category Detail
2006-06-08 Updated TERM Type II site-specific deoxyribonuclease activity
2003-03-19 Updated TERM type II site-specific deoxyribonuclease activity
2002-02-06 Updated TERM type II site-specific deoxyribonuclease
2001-04-03 Updated TERM type II site-specific deoxyribonuclease
2001-03-30 Added TERM type II site-specific deoxyribonuclease

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.
2008-05-12 Deleted DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.
2007-08-09 Added SYNONYM Type II restriction enzyme activity
2007-08-09 Deleted SYNONYM Type II restriction enzyme activity
2006-06-08 Added SYNONYM Type II restriction enzyme activity
2006-06-06 Updated DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.
2002-11-27 Added DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016888 (endodeoxyribonuclease activity, producing 5'-phosphomonoesters)
2008-04-01 Updated RELATION is a GO:0015666 (restriction endodeoxyribonuclease activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:3.1.21.4-RXN
2001-03-30 Added XREF EC:3.1.21.4
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