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GO:0009035 Type I site-specific deoxyribonuclease activity

Term Information

ID GO:0009035
Name Type I site-specific deoxyribonuclease activity
Ontology Molecular Function
Definition Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA.
PMID:15788748
GONUTS GO:0009035 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
exact Type I restriction enzyme activity
exact deoxyribonuclease (adenosine triphosphate-hydrolyzing)
exact type I site-specific deoxyribonuclease activity
exact deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)
exact adenosine triphosphate-dependent deoxyribonuclease activity
exact ATP-dependent DNase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.1.21.3
InterPro IPR004473
MetaCyc 3.1.21.3-RXN

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0009035:
Relationship To GO:0009035 Child Term Child Term Name
Capable of GO:0019812 Type I site-specific deoxyribonuclease complex
Negatively regulates GO:0032080 negative regulation of Type I site-specific deoxyribonuclease activity
Regulates GO:0032084 regulation of Type I site-specific deoxyribonuclease activity

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Identifier
GO Term Name
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Original GO ID
Original GO Term Name
Evidence
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0009035. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0009035 based on the entire annotation set Co-occurrence statistics for GO:0009035 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA.
2008-05-12 Deleted DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA.
2008-04-01 Updated RELATION is a GO:0016888 (endodeoxyribonuclease activity, producing 5'-phosphomonoesters)
2008-04-01 Updated RELATION is a GO:0015666 (restriction endodeoxyribonuclease activity)
2007-11-08 Added SYNONYM adenosine triphosphate-dependent deoxyribonuclease activity
2007-11-08 Added SYNONYM deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)
2007-11-08 Added SYNONYM deoxyribonuclease (adenosine triphosphate-hydrolyzing)
2007-11-08 Added SYNONYM type I site-specific deoxyribonuclease activity
2007-11-08 Added SYNONYM ATP-dependent DNase activity
2007-08-09 Added SYNONYM Type I restriction enzyme activity
2007-08-09 Deleted SYNONYM Type I restriction enzyme activity
2006-06-08 Deleted SYNONYM type 1 site-specific deoxyribonuclease activity
2006-06-08 Added SYNONYM Type I restriction enzyme activity
2006-06-08 Updated TERM Type I site-specific deoxyribonuclease activity
2006-06-06 Updated DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA.
2004-04-19 Added SYNONYM type 1 site-specific deoxyribonuclease activity
2004-04-16 Updated TERM type I site-specific deoxyribonuclease activity
2004-04-16 Deleted SYNONYM type I site-specific deoxyribonuclease activity
2004-01-07 Updated TERM type 1 site-specific deoxyribonuclease activity
2004-01-07 Added SYNONYM type I site-specific deoxyribonuclease activity
2003-10-27 Added XREF MetaCyc:3.1.21.3-RXN
2003-03-19 Updated TERM type I site-specific deoxyribonuclease activity
2002-11-27 Added DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphate; ATP is simultaneously hydrolyzed.
2002-02-06 Updated TERM type I site-specific deoxyribonuclease
2001-04-03 Updated TERM type I site-specific deoxyribonuclease
2001-03-30 Added XREF EC:3.1.21.3
2001-03-30 Added TERM type I site-specific deoxyribonuclease

Term

Timestamp Action Category Detail
2006-06-08 Updated TERM Type I site-specific deoxyribonuclease activity
2004-04-16 Updated TERM type I site-specific deoxyribonuclease activity
2004-01-07 Updated TERM type 1 site-specific deoxyribonuclease activity
2003-03-19 Updated TERM type I site-specific deoxyribonuclease activity
2002-02-06 Updated TERM type I site-specific deoxyribonuclease
2001-04-03 Updated TERM type I site-specific deoxyribonuclease
2001-03-30 Added TERM type I site-specific deoxyribonuclease

Definition/synonyms

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA.
2008-05-12 Deleted DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA.
2007-11-08 Added SYNONYM adenosine triphosphate-dependent deoxyribonuclease activity
2007-11-08 Added SYNONYM deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)
2007-11-08 Added SYNONYM deoxyribonuclease (adenosine triphosphate-hydrolyzing)
2007-11-08 Added SYNONYM type I site-specific deoxyribonuclease activity
2007-11-08 Added SYNONYM ATP-dependent DNase activity
2007-08-09 Added SYNONYM Type I restriction enzyme activity
2007-08-09 Deleted SYNONYM Type I restriction enzyme activity
2006-06-08 Deleted SYNONYM type 1 site-specific deoxyribonuclease activity
2006-06-08 Added SYNONYM Type I restriction enzyme activity
2006-06-06 Updated DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA.
2004-04-19 Added SYNONYM type 1 site-specific deoxyribonuclease activity
2004-04-16 Deleted SYNONYM type I site-specific deoxyribonuclease activity
2004-01-07 Added SYNONYM type I site-specific deoxyribonuclease activity
2002-11-27 Added DEFINITION Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphate; ATP is simultaneously hydrolyzed.

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016888 (endodeoxyribonuclease activity, producing 5'-phosphomonoesters)
2008-04-01 Updated RELATION is a GO:0015666 (restriction endodeoxyribonuclease activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:3.1.21.3-RXN
2001-03-30 Added XREF EC:3.1.21.3
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