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GO:0008975 pitrilysin activity

This term is obsolete.
This term was made obsolete because it represents a gene product.

Term Information

ID GO:0008975
Name pitrilysin activity
Ontology Molecular Function
Definition OBSOLETE. Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.
Comment This term was made obsolete because it represents a gene product.
GONUTS GO:0008975 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
related proteinase Pi
related Escherichia coli metalloproteinase Pi
exact protease III activity
exact protease Pi activity
related Escherichia coli protease III
related PTR

Replaced by

This term is obsolete - try one of these terms:
Advice GO Identifier Ontology GO Term Name
Replaced by GO:0004222 Molecular Function metalloendopeptidase activity

Cross-references

Database ID
EC 3.4.24.55
MetaCyc 3.4.24.55-RXN

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008975:
Term has no children

Protein Annotation

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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008975. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008975 based on the entire annotation set Co-occurrence statistics for GO:0008975 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2010-06-08 Updated TERM pitrilysin activity
2008-11-08 Added OBSOLETION replaced_by GO:0004222 (metalloendopeptidase activity)
2008-10-21 Deleted OBSOLETION replaced_by GO:0004222 (metalloendopeptidase activity)
2008-08-18 Added DEFINITION OBSOLETE. Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.
2008-08-18 Deleted DEFINITION Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.
2008-08-18 Added RELATION is a GO:0008369 (obsolete molecular function)
2008-08-18 Deleted RELATION is a GO:0004222 (metalloendopeptidase activity)
2008-08-18 Added OBSOLETION replaced_by GO:0004222 (metalloendopeptidase activity)
2008-05-13 Added DEFINITION Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.
2008-05-12 Deleted DEFINITION Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.
2008-04-01 Updated RELATION is a GO:0004222 (metalloendopeptidase activity)
2007-11-08 Added SYNONYM Escherichia coli metalloproteinase Pi
2007-11-08 Added SYNONYM Escherichia coli protease III
2007-11-08 Added SYNONYM PTR
2007-11-08 Added SYNONYM proteinase Pi
2007-09-06 Added SYNONYM protease III activity
2007-09-06 Added SYNONYM protease Pi activity
2003-10-27 Added XREF MetaCyc:3.4.24.55-RXN
2003-03-19 Updated TERM pitrilysin activity
2002-11-27 Added DEFINITION Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.
2002-02-06 Updated TERM pitrilysin
2001-04-03 Updated TERM pitrilysin
2001-03-30 Added XREF EC:3.4.24.55
2001-03-30 Added TERM pitrilysin

Term

Timestamp Action Category Detail
2010-06-08 Updated TERM pitrilysin activity
2003-03-19 Updated TERM pitrilysin activity
2002-02-06 Updated TERM pitrilysin
2001-04-03 Updated TERM pitrilysin
2001-03-30 Added TERM pitrilysin

Obsoletions

Timestamp Action Category Detail
2008-11-08 Added OBSOLETION replaced_by GO:0004222 (metalloendopeptidase activity)
2008-10-21 Deleted OBSOLETION replaced_by GO:0004222 (metalloendopeptidase activity)
2008-08-18 Added OBSOLETION replaced_by GO:0004222 (metalloendopeptidase activity)

Definition/synonyms

Timestamp Action Category Detail
2008-08-18 Added DEFINITION OBSOLETE. Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.
2008-08-18 Deleted DEFINITION Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.
2008-05-13 Added DEFINITION Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.
2008-05-12 Deleted DEFINITION Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.
2007-11-08 Added SYNONYM Escherichia coli metalloproteinase Pi
2007-11-08 Added SYNONYM Escherichia coli protease III
2007-11-08 Added SYNONYM PTR
2007-11-08 Added SYNONYM proteinase Pi
2007-09-06 Added SYNONYM protease III activity
2007-09-06 Added SYNONYM protease Pi activity
2002-11-27 Added DEFINITION Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.

Relationships

Timestamp Action Category Detail
2010-06-08 Deleted RELATION is a GO:0008369 (obsolete molecular function)
2008-08-18 Added RELATION is a GO:0008369 (obsolete molecular function)
2008-08-18 Deleted RELATION is a GO:0004222 (metalloendopeptidase activity)
2008-04-01 Updated RELATION is a GO:0004222 (metalloendopeptidase activity)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:3.4.24.55-RXN
2001-03-30 Added XREF EC:3.4.24.55
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