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GO:0008900 hydrogen:potassium-exchanging ATPase activity

Term Information

ID GO:0008900
Name hydrogen:potassium-exchanging ATPase activity
Ontology Molecular Function
Definition Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).
Secondary IDs GO:0005390
GONUTS GO:0008900 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow gastric H+/K+ ATPase
exact H,K-ATPase activity
exact H+/K+-exchanging ATPase activity
exact H+/K+-ATPase activity
exact H+-K+-ATPase activity
exact ATP phosphohydrolase (H+/K+-exchanging)
exact H(+)/K(+)-ATPase activity
narrow gastric H(+)/K(+) ATPase activity
exact hydrogen:potassium exchanging ATPase activity
exact hydrogen/potassium-exchanging ATPase activity
broad proton pump activity
exact H(+)/K(+)-exchanging ATPase activity
exact (K+ + H+)-ATPase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 3.6.3.10
InterPro IPR015127
RHEA 22047

Ancestor Chart

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008900:
Relationship To GO:0008900 Child Term Child Term Name
Regulates GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity
Negatively regulates GO:1904452 negative regulation of hydrogen:potassium-exchanging ATPase activity
Positively regulates GO:1904453 positive regulation of hydrogen:potassium-exchanging ATPase activity
Capable of GO:0005889 hydrogen:potassium-exchanging ATPase complex

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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GO Term Name
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Original GO Term Name
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008900. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008900 based on the entire annotation set Co-occurrence statistics for GO:0008900 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2011-10-28 Deleted SYNONYM h+/K+-exchanging ATPase activity
2011-09-16 Added XREF RHEA:22047
2010-06-09 Updated TERM hydrogen:potassium-exchanging ATPase activity
2010-06-08 Updated TERM hydrogen:potassium-exchanging ATPase activity
2010-06-04 Added RELATION is a GO:0008556 (potassium-transporting ATPase activity)
2010-06-04 Deleted RELATION is a GO:0015662 (ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism)
2009-05-21 Deleted XREF MetaCyc:3.6.3.10-RXN
2008-05-13 Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).
2008-04-01 Updated RELATION is a GO:0015662 (ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism)
2008-04-01 Updated RELATION is a GO:0015078 (hydrogen ion transmembrane transporter activity)
2007-11-08 Added SYNONYM (K+ + H+)-ATPase activity
2007-11-08 Added SYNONYM ATP phosphohydrolase (H+/K+-exchanging)
2007-11-08 Added SYNONYM H+-K+-ATPase activity
2007-11-08 Added SYNONYM H+/K+-ATPase activity
2007-11-08 Added SYNONYM H+/K+-exchanging ATPase activity
2007-11-08 Added SYNONYM H,K-ATPase activity
2007-11-08 Added SYNONYM gastric H+/K+ ATPase
2007-11-08 Added SYNONYM h+/K+-exchanging ATPase activity
2007-09-06 Added SYNONYM H(+)/K(+)-ATPase activity
2007-09-06 Added SYNONYM H(+)/K(+)-exchanging ATPase activity
2007-09-06 Added SYNONYM gastric H(+)/K(+) ATPase activity
2007-09-06 Added SYNONYM proton pump activity
2007-09-06 Deleted SYNONYM proton pump
2007-08-09 Added SYNONYM hydrogen:potassium exchanging ATPase activity
2007-08-09 Added SYNONYM proton pump
2007-08-09 Added SYNONYM hydrogen/potassium-exchanging ATPase activity
2007-08-09 Deleted SYNONYM hydrogen/potassium-exchanging ATPase activity
2007-08-09 Deleted SYNONYM hydrogen:potassium exchanging ATPase activity
2007-08-09 Deleted SYNONYM proton pump
2007-07-27 Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).
2005-07-29 Added SYNONYM hydrogen:potassium exchanging ATPase activity
2004-07-26 Added SYNONYM hydrogen/potassium-exchanging ATPase activity
2004-07-26 Updated TERM hydrogen:potassium-exchanging ATPase activity
2004-04-19 Added SYNONYM proton pump
2004-04-16 Deleted SYNONYM proton pump
2003-10-27 Added SYNONYM proton pump
2003-10-27 Added XREF MetaCyc:3.6.3.10-RXN
2003-08-21 Deleted SYNONYM proton pump
2003-03-26 Updated DEFINITION Catalysis of the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).
2003-03-19 Updated TERM hydrogen/potassium-exchanging ATPase activity
2002-11-27 Updated DEFINITION A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. Catalyzes the efflux of one hydrogen ion and the influx of one potassium ion per ATP hydrolyzed.
2002-02-06 Updated TERM hydrogen/potassium-exchanging ATPase
2001-08-06 Added DEFINITION A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. Catalyses the efflux of one hydrogen ion and the influx of one potassium ion per ATP hydrolysed.
2001-04-03 Updated TERM hydrogen/potassium-exchanging ATPase
2001-03-30 Added XREF EC:3.6.3.10
2001-03-30 Added SYNONYM proton pump
2001-03-30 Added TERM hydrogen/potassium-exchanging ATPase

Term

Timestamp Action Category Detail
2010-06-09 Updated TERM hydrogen:potassium-exchanging ATPase activity
2010-06-08 Updated TERM hydrogen:potassium-exchanging ATPase activity
2004-07-26 Updated TERM hydrogen:potassium-exchanging ATPase activity
2003-03-19 Updated TERM hydrogen/potassium-exchanging ATPase activity
2002-02-06 Updated TERM hydrogen/potassium-exchanging ATPase
2001-04-03 Updated TERM hydrogen/potassium-exchanging ATPase
2001-03-30 Added TERM hydrogen/potassium-exchanging ATPase

Definition/synonyms

Timestamp Action Category Detail
2011-10-28 Deleted SYNONYM h+/K+-exchanging ATPase activity
2008-05-13 Added DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).
2008-05-12 Deleted DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).
2007-11-08 Added SYNONYM (K+ + H+)-ATPase activity
2007-11-08 Added SYNONYM ATP phosphohydrolase (H+/K+-exchanging)
2007-11-08 Added SYNONYM H+-K+-ATPase activity
2007-11-08 Added SYNONYM H+/K+-ATPase activity
2007-11-08 Added SYNONYM H+/K+-exchanging ATPase activity
2007-11-08 Added SYNONYM H,K-ATPase activity
2007-11-08 Added SYNONYM gastric H+/K+ ATPase
2007-11-08 Added SYNONYM h+/K+-exchanging ATPase activity
2007-09-06 Added SYNONYM H(+)/K(+)-ATPase activity
2007-09-06 Added SYNONYM H(+)/K(+)-exchanging ATPase activity
2007-09-06 Added SYNONYM gastric H(+)/K(+) ATPase activity
2007-09-06 Added SYNONYM proton pump activity
2007-09-06 Deleted SYNONYM proton pump
2007-08-09 Added SYNONYM hydrogen:potassium exchanging ATPase activity
2007-08-09 Added SYNONYM proton pump
2007-08-09 Added SYNONYM hydrogen/potassium-exchanging ATPase activity
2007-08-09 Deleted SYNONYM hydrogen/potassium-exchanging ATPase activity
2007-08-09 Deleted SYNONYM hydrogen:potassium exchanging ATPase activity
2007-08-09 Deleted SYNONYM proton pump
2007-07-27 Updated DEFINITION Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).
2005-07-29 Added SYNONYM hydrogen:potassium exchanging ATPase activity
2004-07-26 Added SYNONYM hydrogen/potassium-exchanging ATPase activity
2004-04-19 Added SYNONYM proton pump
2004-04-16 Deleted SYNONYM proton pump
2003-10-27 Added SYNONYM proton pump
2003-08-21 Deleted SYNONYM proton pump
2003-03-26 Updated DEFINITION Catalysis of the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).
2002-11-27 Updated DEFINITION A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. Catalyzes the efflux of one hydrogen ion and the influx of one potassium ion per ATP hydrolyzed.
2001-08-06 Added DEFINITION A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. Catalyses the efflux of one hydrogen ion and the influx of one potassium ion per ATP hydrolysed.
2001-03-30 Added SYNONYM proton pump

Relationships

Timestamp Action Category Detail
2010-06-04 Added RELATION is a GO:0008556 (potassium-transporting ATPase activity)
2010-06-04 Deleted RELATION is a GO:0015662 (ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism)
2008-04-01 Updated RELATION is a GO:0015662 (ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism)
2008-04-01 Updated RELATION is a GO:0015078 (hydrogen ion transmembrane transporter activity)

Cross-references

Timestamp Action Category Detail
2011-09-16 Added XREF RHEA:22047
2009-05-21 Deleted XREF MetaCyc:3.6.3.10-RXN
2003-10-27 Added XREF MetaCyc:3.6.3.10-RXN
2001-03-30 Added XREF EC:3.6.3.10
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