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GO:0008897 holo-[acyl-carrier-protein] synthase activity

Term Information

ID GO:0008897
Name holo-[acyl-carrier-protein] synthase activity
Ontology Molecular Function
Definition Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
PMID:10320345 PMID:11867633 PMID:8939709
Secondary IDs GO:0008958
GONUTS GO:0008897 Wiki Page

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope. Click on the icon for more details.
Type Synonym
narrow holo-[peptidyl-carrier protein] synthase activity
narrow holo-[acyl-carrier-protein] synthase activity
exact 4'-phosphopantetheinyltransferase activity
exact phosphopantetheinyltransferase activity
exact alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity
exact CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity
exact CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity
related AcpS
exact 4'-phosphopantetheinyl transferase activity
exact holo-acyl-carrier-protein synthase activity
exact coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity
related holosynthase activity
related holo-ACP synthetase activity
related holo-ACP synthase activity
exact alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity
related acyl carrier protein synthetase activity
related acyl carrier protein synthase activity
exact acyl carrier protein holoprotein (holo-ACP) synthetase activity
exact PPTase activity
exact P-pant transferase activity
related ACPS activity
narrow L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity
exact alpha-aminoadipate reductase phosphopantetheinyl transferase activity

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:
Annotation Guidelines
Annotating to catalytic activities using the IPI evidence codeLink
Describing enzyme functions that catalyse multi-stage reactionsLink

Cross-references

Database ID
EC 2.7.8.7
InterPro IPR002582
InterPro IPR004568
InterPro IPR008278
InterPro IPR016614
MetaCyc HOLO-ACP-SYNTH-RXN

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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0008897:
Term has no children

Protein Annotation

Displaying annotations FIRST to LAST of TOTAL Page size: Additional filters: Bookmarkable link
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Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated with GO:0008897. The terms are listed in descending order of number of times the term has been co-annotated.
The table on the left is calculated using both electronic and manual-evidenced annotations, while the table on the right is calculated using only manual-evidenced annotations.
Co-occurrence statistics for GO:0008897 based on the entire annotation set Co-occurrence statistics for GO:0008897 based on non-IEA annotations only

Change Log

All changes

Timestamp Action Category Detail
2008-05-24 Updated TERM holo-[acyl-carrier-protein] synthase activity
2008-05-24 Added SYNONYM phosphopantetheinyltransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
2008-04-01 Updated RELATION is a GO:0016780 (phosphotransferase activity, for other substituted phosphate groups)
2007-12-14 Added SYNONYM AcpS
2007-12-14 Added SYNONYM CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity
2007-12-14 Added SYNONYM CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity
2007-12-14 Added SYNONYM alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity
2007-12-14 Added SYNONYM coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity
2007-12-14 Added SYNONYM holo-acyl-carrier-protein synthase activity
2007-11-08 Deleted SYNONYM alpha-aminoadipate reductase phosphopantetheinyl transferase
2007-11-08 Added SYNONYM alpha-aminoadipate reductase phosphopantetheinyl transferase activity
2007-09-06 Added SYNONYM 4'-phosphopantetheinyl transferase activity
2007-09-06 Added SYNONYM ACPS activity
2007-09-06 Added SYNONYM L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity
2007-09-06 Added SYNONYM P-pant transferase activity
2007-09-06 Added SYNONYM PPTase activity
2007-09-06 Added SYNONYM acyl carrier protein holoprotein (holo-ACP) synthetase activity
2007-09-06 Added SYNONYM acyl carrier protein synthase activity
2007-09-06 Added SYNONYM acyl carrier protein synthetase activity
2007-09-06 Added SYNONYM alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity
2007-09-06 Added SYNONYM holo-ACP synthase activity
2007-09-06 Added SYNONYM holo-ACP synthetase activity
2007-09-06 Added SYNONYM holosynthase activity
2007-09-06 Deleted SYNONYM PPTase
2007-09-06 Deleted SYNONYM holo-ACP synthase activity
2007-09-06 Deleted SYNONYM holo-PCP synthase activity
2007-08-09 Added SYNONYM 4'-phosphopantetheinyltransferase activity
2007-08-09 Added SYNONYM PPTase
2007-08-09 Added SYNONYM alpha-aminoadipate reductase phosphopantetheinyl transferase
2007-08-09 Added SYNONYM holo-ACP synthase activity
2007-08-09 Added SYNONYM holo-PCP synthase activity
2007-08-09 Added SYNONYM holo-[acyl-carrier-protein] synthase activity
2007-08-09 Added SYNONYM holo-[peptidyl-carrier protein] synthase activity
2007-08-09 Deleted SYNONYM 4'-phosphopantetheinyltransferase activity
2007-08-09 Deleted SYNONYM PPTase
2007-08-09 Deleted SYNONYM alpha-aminoadipate reductase phosphopantetheinyl transferase
2007-08-09 Deleted SYNONYM holo-ACP synthase activity
2007-08-09 Deleted SYNONYM holo-PCP synthase activity
2007-08-09 Deleted SYNONYM holo-[acyl-carrier-protein] synthase activity
2007-08-09 Deleted SYNONYM holo-[peptidyl-carrier protein] synthase activity
2007-07-12 Added SYNONYM 4'-phosphopantetheinyltransferase activity
2006-11-25 Deleted SYNONYM holo-[acyl-carrier protein] synthase activity
2006-11-25 Added SYNONYM holo-[acyl-carrier-protein] synthase activity
2004-12-09 Added SYNONYM PPTase
2004-12-09 Added SYNONYM alpha-aminoadipate reductase phosphopantetheinyl transferase
2004-10-31 Added SYNONYM holo-[acyl-carrier protein] synthase activity
2004-10-31 Updated TERM phosphopantetheinyltransferase activity
2004-10-31 Added SYNONYM holo-PCP synthase activity
2004-10-31 Deleted SYNONYM phosphopantetheinyltransferase activity
2004-10-31 Added SYNONYM holo-[peptidyl-carrier protein] synthase activity
2004-10-30 Updated DEFINITION Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
2004-04-19 Added SYNONYM holo-ACP synthase activity
2004-04-19 Added SYNONYM phosphopantetheinyltransferase activity
2004-04-16 Deleted SYNONYM holo-ACP synthase activity
2004-04-16 Deleted SYNONYM phosphopantetheinyltransferase activity
2003-10-27 Added SYNONYM holo-ACP synthase activity
2003-10-27 Added SYNONYM phosphopantetheinyltransferase activity
2003-10-27 Added XREF MetaCyc:HOLO-ACP-SYNTH-RXN
2003-10-24 Updated DEFINITION Catalysis of the reaction: CoA + apo-[acyl-carrier protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein].
2003-08-20 Deleted SYNONYM phosphopantetheinyltransferase activity
2003-05-01 Added SYNONYM phosphopantetheinyltransferase activity
2003-05-01 Added SECONDARY GO:0008958 (phosphopantetheinyltransferase activity)
2003-04-24 Updated DEFINITION Catalysis of the reaction: CoA + apo-(acyl-carrier protein) = adenosine 3',5'-bisphosphate + holo-(acyl-carrier protein).
2003-03-19 Updated TERM holo-[acyl-carrier protein] synthase activity
2002-11-27 Added DEFINITION Catalysis of the reaction: CoA + apo-[acyl-carrier protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein].
2002-02-06 Updated TERM holo-[acyl-carrier protein] synthase
2001-04-03 Updated TERM holo-[acyl-carrier protein] synthase
2001-03-30 Added XREF EC:2.7.8.7
2001-03-30 Added TERM holo-[acyl-carrier protein] synthase

Term

Timestamp Action Category Detail
2008-05-24 Updated TERM holo-[acyl-carrier-protein] synthase activity
2004-10-31 Updated TERM phosphopantetheinyltransferase activity
2003-03-19 Updated TERM holo-[acyl-carrier protein] synthase activity
2002-02-06 Updated TERM holo-[acyl-carrier protein] synthase
2001-04-03 Updated TERM holo-[acyl-carrier protein] synthase
2001-03-30 Added TERM holo-[acyl-carrier protein] synthase

Definition/synonyms

Timestamp Action Category Detail
2008-05-24 Added SYNONYM phosphopantetheinyltransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
2007-12-14 Added SYNONYM AcpS
2007-12-14 Added SYNONYM CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity
2007-12-14 Added SYNONYM CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity
2007-12-14 Added SYNONYM alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity
2007-12-14 Added SYNONYM coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity
2007-12-14 Added SYNONYM holo-acyl-carrier-protein synthase activity
2007-11-08 Deleted SYNONYM alpha-aminoadipate reductase phosphopantetheinyl transferase
2007-11-08 Added SYNONYM alpha-aminoadipate reductase phosphopantetheinyl transferase activity
2007-09-06 Added SYNONYM 4'-phosphopantetheinyl transferase activity
2007-09-06 Added SYNONYM ACPS activity
2007-09-06 Added SYNONYM L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity
2007-09-06 Added SYNONYM P-pant transferase activity
2007-09-06 Added SYNONYM PPTase activity
2007-09-06 Added SYNONYM acyl carrier protein holoprotein (holo-ACP) synthetase activity
2007-09-06 Added SYNONYM acyl carrier protein synthase activity
2007-09-06 Added SYNONYM acyl carrier protein synthetase activity
2007-09-06 Added SYNONYM alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity
2007-09-06 Added SYNONYM holo-ACP synthase activity
2007-09-06 Added SYNONYM holo-ACP synthetase activity
2007-09-06 Added SYNONYM holosynthase activity
2007-09-06 Deleted SYNONYM PPTase
2007-09-06 Deleted SYNONYM holo-ACP synthase activity
2007-09-06 Deleted SYNONYM holo-PCP synthase activity
2007-08-09 Added SYNONYM 4'-phosphopantetheinyltransferase activity
2007-08-09 Added SYNONYM PPTase
2007-08-09 Added SYNONYM alpha-aminoadipate reductase phosphopantetheinyl transferase
2007-08-09 Added SYNONYM holo-ACP synthase activity
2007-08-09 Added SYNONYM holo-PCP synthase activity
2007-08-09 Added SYNONYM holo-[acyl-carrier-protein] synthase activity
2007-08-09 Added SYNONYM holo-[peptidyl-carrier protein] synthase activity
2007-08-09 Deleted SYNONYM 4'-phosphopantetheinyltransferase activity
2007-08-09 Deleted SYNONYM PPTase
2007-08-09 Deleted SYNONYM alpha-aminoadipate reductase phosphopantetheinyl transferase
2007-08-09 Deleted SYNONYM holo-ACP synthase activity
2007-08-09 Deleted SYNONYM holo-PCP synthase activity
2007-08-09 Deleted SYNONYM holo-[acyl-carrier-protein] synthase activity
2007-08-09 Deleted SYNONYM holo-[peptidyl-carrier protein] synthase activity
2007-07-12 Added SYNONYM 4'-phosphopantetheinyltransferase activity
2006-11-25 Deleted SYNONYM holo-[acyl-carrier protein] synthase activity
2006-11-25 Added SYNONYM holo-[acyl-carrier-protein] synthase activity
2004-12-09 Added SYNONYM PPTase
2004-12-09 Added SYNONYM alpha-aminoadipate reductase phosphopantetheinyl transferase
2004-10-31 Added SYNONYM holo-[acyl-carrier protein] synthase activity
2004-10-31 Added SYNONYM holo-PCP synthase activity
2004-10-31 Deleted SYNONYM phosphopantetheinyltransferase activity
2004-10-31 Added SYNONYM holo-[peptidyl-carrier protein] synthase activity
2004-10-30 Updated DEFINITION Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
2004-04-19 Added SYNONYM holo-ACP synthase activity
2004-04-19 Added SYNONYM phosphopantetheinyltransferase activity
2004-04-16 Deleted SYNONYM holo-ACP synthase activity
2004-04-16 Deleted SYNONYM phosphopantetheinyltransferase activity
2003-10-27 Added SYNONYM holo-ACP synthase activity
2003-10-27 Added SYNONYM phosphopantetheinyltransferase activity
2003-10-24 Updated DEFINITION Catalysis of the reaction: CoA + apo-[acyl-carrier protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein].
2003-08-20 Deleted SYNONYM phosphopantetheinyltransferase activity
2003-05-01 Added SYNONYM phosphopantetheinyltransferase activity
2003-04-24 Updated DEFINITION Catalysis of the reaction: CoA + apo-(acyl-carrier protein) = adenosine 3',5'-bisphosphate + holo-(acyl-carrier protein).
2002-11-27 Added DEFINITION Catalysis of the reaction: CoA + apo-[acyl-carrier protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier protein].

Relationships

Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016780 (phosphotransferase activity, for other substituted phosphate groups)

Cross-references

Timestamp Action Category Detail
2003-10-27 Added XREF MetaCyc:HOLO-ACP-SYNTH-RXN
2001-03-30 Added XREF EC:2.7.8.7

Other

Timestamp Action Category Detail
2003-05-01 Added SECONDARY GO:0008958 (phosphopantetheinyltransferase activity)
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