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GO:0008897 holo-[acyl-carrier-protein] synthase activityCatalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
Term Information
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| Type | Synonym |
| exact | phosphopantetheinyltransferase activity |
| exact | alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity |
| exact | CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity |
| exact | CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity |
| related | AcpS |
| exact | holo-acyl-carrier-protein synthase activity |
| exact | coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity |
| related | acyl carrier protein synthase activity |
| exact | acyl carrier protein holoprotein (holo-ACP) synthetase activity |
| exact | PPTase activity |
| exact | P-pant transferase activity |
| narrow | L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity |
| related | ACPS activity |
| exact | 4'-phosphopantetheinyl transferase activity |
| related | holosynthase activity |
| related | holo-ACP synthetase activity |
| related | holo-ACP synthase activity |
| related | acyl carrier protein synthetase activity |
| exact | alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity |
| exact | alpha-aminoadipate reductase phosphopantetheinyl transferase activity |
| narrow | holo-[peptidyl-carrier protein] synthase activity |
| narrow | holo-[acyl-carrier-protein] synthase activity |
| exact | 4'-phosphopantetheinyltransferase activity |
| Database | ID |
| INTERPRO | IPR016614 |
| MetaCyc | HOLO-ACP-SYNTH-RXN |
| EC | 2.7.8.7 |
| INTERPRO | IPR008278 |
| INTERPRO | IPR002582 |
| INTERPRO | IPR004568 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | |||||
![]() | GO:0003824 catalytic activity | ||||
![]() | ![]() | GO:0016740 transferase activity | |||
![]() | ![]() | ![]() | GO:0016772 transferase activity, transferring phosphorus-containing groups | ||
![]() | ![]() | ![]() | ![]() | GO:0016780 phosphotransferase activity, for other substituted phosphate groups | |
![]() | ![]() | ![]() | ![]() | ![]() | GO:0008897 holo-[acyl-carrier-protein] synthase activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-8.ebi.ac.uk |
| Uptime | 17:46 13/10/2009 |
| Data version | 2009-11-21-04-03-45 |