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GO:0008750 NAD(P)+ transhydrogenase (AB-specific) activityCatalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD+ and B-specific (i.e. the pro-S hydrogen is transferred) with respect to NADP+.
Term Information
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| Type | Synonym |
| broad | transhydrogenase activity |
| exact | NAD(P) transhydrogenase (AB-specific) activity |
| broad | pyridine nucleotide transhydrogenase activity |
| exact | NADPH:NAD+ oxidoreductase (AB-specific) |
| Database | ID |
| EC | 1.6.1.2 |
| MetaCyc | 1.6.1.2-RXN |
| INTERPRO | IPR012136 |
| INTERPRO | IPR004571 |
All GO terms displayed in this graph can be clicked to display term definitions and child (descendent) terms.
All GO terms displayed in this chart can be right-clicked to display term definitions and child (descendent) terms.
| GO:0003674 molecular_function | ||||||
![]() | GO:0003824 catalytic activity | |||||
![]() | ![]() | GO:0016491 oxidoreductase activity | ||||
![]() | ![]() | ![]() | GO:0016651 oxidoreductase activity, acting on NADH or NADPH | |||
![]() | ![]() | ![]() | ![]() | GO:0016652 oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor | ||
![]() | ![]() | ![]() | ![]() | ![]() | GO:0008746 NAD(P) transhydrogenase activity | |
![]() | ![]() | ![]() | ![]() | ![]() | ![]() | GO:0008750 NAD(P)+ transhydrogenase (AB-specific) activity |
| Code | Relationship |
![]() | part of |
![]() | is a |
![]() | regulates |
![]() | +ve regulates |
![]() | -ve regulates |
| Hostname | tomcat-7.ebi.ac.uk |
| Uptime | 16:38 12/10/2009 |
| Data version | 2009-11-22-04-02-35 |